Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Atsuro Takeshita"'
Autor:
Suphachai Tharavecharak, Hajime Fujimoto, Taro Yasuma, Corina N. D’Alessandro-Gabazza, Masaaki Toda, Atsushi Tomaru, Haruko Saiki, Mei Uemura, Yurie Kogue, Toshiyuki Ito, Kazuki Furuhashi, Tomohito Okano, Atsuro Takeshita, Kota Nishihama, Ryoichi Ono, Osamu Hataji, Tetsuya Nosaka, Tetsu Kobayashi, Esteban C. Gabazza
Publikováno v:
Cells, Vol 13, Iss 18, p 1523 (2024)
Idiopathic pulmonary fibrosis (IPF) is a progressive, often fatal lung disease characterized by tissue scarring and declining lung function. The MUC5B promoter polymorphism rs35705950, a significant genetic predisposition for IPF, paradoxically assoc
Externí odkaz:
https://doaj.org/article/a7b349c579fe42088391e7abf4def2b0
Autor:
Corina N. D’Alessandro-Gabazza, Taro Yasuma, Tetsu Kobayashi, Masaaki Toda, Ahmed M. Abdel-Hamid, Hajime Fujimoto, Osamu Hataji, Hiroki Nakahara, Atsuro Takeshita, Kota Nishihama, Tomohito Okano, Haruko Saiki, Yuko Okano, Atsushi Tomaru, Valeria Fridman D’Alessandro, Miyako Shiraishi, Akira Mizoguchi, Ryoichi Ono, Junpei Ohtsuka, Masayuki Fukumura, Tetsuya Nosaka, Xuenan Mi, Diwakar Shukla, Kensuke Kataoka, Yasuhiro Kondoh, Masaki Hirose, Toru Arai, Yoshikazu Inoue, Yutaka Yano, Roderick I. Mackie, Isaac Cann, Esteban C. Gabazza
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-23 (2022)
Here, the authors show that treatment with a monoclonal neutralizing antibody against the lung microbiota-derived proapoptotic peptide corisin ameliorates acute exacerbation of pulmonary fibrosis and severity of endotoxin-induced acute lung injury in
Externí odkaz:
https://doaj.org/article/c55325ad1d4042ecbf6c24f945542d94
Autor:
Ryo Inoue, Taro Yasuma, Valeria Fridman D’Alessandro, Masaaki Toda, Toshiyuki Ito, Atsushi Tomaru, Corina N. D’Alessandro-Gabazza, Tatsuki Tsuruga, Tomohito Okano, Atsuro Takeshita, Kota Nishihama, Hajime Fujimoto, Tetsu Kobayashi, Esteban C. Gabazza
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6695 (2023)
Idiopathic pulmonary fibrosis is a progressive and fatal disease with a poor prognosis. Matrix metalloproteinase-2 is involved in the pathogenesis of organ fibrosis. The role of matrix metalloproteinase-2 in lung fibrosis is unclear. This study evalu
Externí odkaz:
https://doaj.org/article/c319c606b65642f4971d1759ca55383f
Autor:
Corina N. D’Alessandro-Gabazza, Tetsu Kobayashi, Taro Yasuma, Masaaki Toda, Heejin Kim, Hajime Fujimoto, Osamu Hataji, Atsuro Takeshita, Kota Nishihama, Tomohito Okano, Yuko Okano, Yoichi Nishii, Atsushi Tomaru, Kentaro Fujiwara, Valeria Fridman D’Alessandro, Ahmed M. Abdel-Hamid, Yudong Ren, Gabriel V. Pereira, Christy L. Wright, Alvaro Hernandez, Christopher J. Fields, Peter M. Yau, Shujie Wang, Akira Mizoguchi, Masayuki Fukumura, Junpei Ohtsuka, Tetsuya Nosaka, Kensuke Kataoka, Yasuhiro Kondoh, Jing Wu, Hirokazu Kawagishi, Yutaka Yano, Roderick I. Mackie, Isaac Cann, Esteban C. Gabazza
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Idiopathic pulmonary fibrosis is associated with increased abundance of Staphylococcus and Streptococcus in the lungs. Here, the authors identify a Staphylococcus nepalensis-derived peptide, named corisin, to induce apoptosis of lung epithelial cells
Externí odkaz:
https://doaj.org/article/24d6379d02ba4aa196a47557ce97486e
Autor:
Valeria Fridman D’Alessandro, Atsuro Takeshita, Taro Yasuma, Masaaki Toda, Corina N. D’Alessandro-Gabazza, Yuko Okano, Suphachai Tharavecharak, Chisa Inoue, Kota Nishihama, Hajime Fujimoto, Tetsu Kobayashi, Yutaka Yano, Esteban C. Gabazza
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14265 (2022)
Diabetes mellitus is a global health problem. Diabetic nephropathy is a common complication of diabetes mellitus and the leading cause of end-stage renal disease. The clinical course, response to therapy, and prognosis of nephropathy are worse in dia
Externí odkaz:
https://doaj.org/article/9b6abc26fb3e4650967593a8ca819270
Autor:
Tomohito Okano, Tetsu Kobayashi, Taro Yasuma, Corina N. D’Alessandro-Gabazza, Masaaki Toda, Hajime Fujimoto, Hiroki Nakahara, Yuko Okano, Atsuro Takeshita, Kota Nishihama, Haruko Saiki, Atsushi Tomaru, Valeria Fridman D’Alessandro, Satoru Ishida, Hiromi Sugimoto, Yoshiyuki Takei, Esteban C. Gabazza
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Idiopathic pulmonary fibrosis is a chronic, progressive, and lethal lung disease of unknown etiology. Antifibrotic drugs, including pirfenidone, are currently used for the treatment of the disease. The oral administration of pirfenidone is an effecti
Externí odkaz:
https://doaj.org/article/efcc9395978b4f508fef940bd7451fc3
Autor:
Chisa Inoue, Taro Yasuma, Corina N. D’Alessandro-Gabazza, Masaaki Toda, Valeria Fridman D’Alessandro, Ryo Inoue, Hajime Fujimoto, Hajime Kobori, Suphachai Tharavecharak, Atsuro Takeshita, Kota Nishihama, Yuko Okano, Jing Wu, Tetsu Kobayashi, Yutaka Yano, Hirokazu Kawagishi, Esteban C. Gabazza
Publikováno v:
Cells, Vol 11, Iss 3, p 374 (2022)
The leading cause of death worldwide is cancer. Many reports have proved the beneficial effect of mushrooms in cancer. However, the precise mechanism is not completely clear. In the present study, we focused on the medicinal properties of biomolecule
Externí odkaz:
https://doaj.org/article/0aa95383e7944e0ab69b09aa02c37f7d
Autor:
Fumine Tanaka, MD, Ryota Kogue, MD, Masayuki Maeda, MD, PhD, Maki Umino, MD, PhD, Yasuo Nakai, MD, Atsuro Takeshita, MD, Hajime Sakuma, MD, PhD
Publikováno v:
Radiology Case Reports, Vol 13, Iss 1, Pp 261-264 (2018)
Ipilimumab, a human monoclonal antibody against cytotoxic T-lymphocyte antigen 4, was approved by the U.S. FDA (Food and Drug Administration) in 2011 for the treatment of unresectable or metastatic malignant melanoma. Occurrence of hypophysitis, an i
Externí odkaz:
https://doaj.org/article/eaef899e23e64ae5b25ac0bddb6a8fbb
Autor:
Haruko Saiki, Yuko Okano, Taro Yasuma, Masaaki Toda, Atsuro Takeshita, Ahmed M. Abdel-Hamid, Valeria Fridman D’Alessandro, Tatsuki Tsuruga, Corina N. D’Alessandro-Gabazza, Kan Katayama, Masahiko Sugimoto, Hajime Fujimoto, Keiichi Yamanaka, Tetsu Kobayashi, Isaac Cann, Esteban C. Gabazza
Publikováno v:
Cells, Vol 10, Iss 11, p 2885 (2021)
Apoptosis is a programmed cell death involved in embryogenesis and tissue homeostasis under physiological conditions. However, abnormalities in the process of apoptosis are implicated in the pathogenesis of various diseases. The human microbiota may
Externí odkaz:
https://doaj.org/article/971803f952d24a18bd9b34477a1ec30b
Autor:
Yuko Okano, Atsuro Takeshita, Taro Yasuma, Masaaki Toda, Kota Nishihama, Valeria Fridman D’Alessandro, Chisa Inoue, Corina N. D’Alessandro-Gabazza, Tetsu Kobayashi, Yutaka Yano, Esteban C. Gabazza
Publikováno v:
Cells, Vol 10, Iss 9, p 2237 (2021)
Diabetes mellitus is a global threat to human health. The ultimate cause of diabetes mellitus is insufficient insulin production and secretion associated with reduced pancreatic β-cell mass. Apoptosis is an important and well-recognized mechanism of
Externí odkaz:
https://doaj.org/article/647b24029ab94520b2dba493a7ab270d