Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Atsuo MIYAGISHIMA"'
Autor:
Shigeru Itai, Takeru Iwamura, Shoko Tanaka, Takeaki Uchimoto, Kana Takahashi, Yasunori Iwao, Atsuo Miyagishima, Yasuyoshi Agata
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 78:492-498
To study the effect of glycerin fatty acid ester (Poem TR-FB) concentrations on the dissolution rate of acetaminophen (APAP), the dissolution and disintegration behaviors of APAP tablets formulated using various lubricants were examined. The change o
Publikováno v:
International Journal of Pharmaceutics. 414:63-68
To predict drug dissolution and understand the mechanisms of drug release from wax matrix dosage forms containing glyceryl monostearate (GM; a wax base), aminoalkyl methacrylate copolymer E (AMCE; a pH-dependent functional polymer), and acetaminophen
Autor:
Aya Okimura, Shinsuke Inagaki, Yasunori Iwao, Atsuo Miyagishima, Shigeru Itai, Sakae Arahata, Sadahiro Fujiki
Publikováno v:
Food Chemistry. 125:878-883
We have recently succeeded in manufacturing low-caffeine tea (LCT) by employing a special picking method in the 3rd leaf period and shortening the leaf-rolling process. In the present study, the effect of this special method on the content of other p
Publikováno v:
Chemical and Pharmaceutical Bulletin. 59:553-558
It has been reported that tablets of clarithromycin (CAM), a 14-membered macrolide antibiotic, are especially stable under low pH conditions such as in gastric fluid, and showed excellent antibacterial efficiency even though CAM molecules themselves
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 74:461-466
Size reduction of drug particles to the nanoscale is important in improving the dissolution rate of poorly water-soluble drugs. The aim of this study was to investigate the physicochemical properties of griseofulvin (GF)-lipid nanoparticles and the i
Autor:
Shigeru Itai, Takeaki Uchimoto, Takashi Sonobe, Atsuo Miyagishima, Yuki Ikegami, Yasunori Iwao, Takashi Murata
Publikováno v:
International Journal of Pharmaceutics. 386:91-98
To study the usefulness of glycerin fatty acid ester Poem TR-FB (TR-FB) and Poem TR-HB (TR-HB) as lubricants, pressure transmission ratio, ejection force, disintegration time, and tensile strength were measured at different concentrations and mixing
Autor:
Atsuo Miyagishima, Seitaro Kamiya, Takashi Sonobe, Mariko Yamada, Masayuki Arakawa, Takurou Kurita
Publikováno v:
International Journal of Pharmaceutics. 354:242-247
Design methods of nanoparticle formulations are divided into a break-down method and a build-up method. Furthermore, the former is further divided into dry and wet processes. For drug nanoparticle preparations, the wet process is generally employed,
Publikováno v:
KAGAKU KOGAKU RONBUNSHU. 30:43-46
水難溶性薬物の溶解促進を目指す薬物粒子微細懸液の調製と, その長期安定保存を目的とする凍結乾燥再水和処理による微細懸濁液の粒子径の保持に及ぼす糖類の添加効果について調べ
Autor:
Akiko Nakade, Rieko Hirama, Takashi Sonobe, Atsuo Miyagishima, Yasuyuki Sadzuka, Yasuo Nozawa, Sadao Hirota
Publikováno v:
International Journal of Pharmaceutics. 238:171-180
Polyethyleneglycol (PEG) has often been used for the modification of liposomes, but it is difficult to insert PEG on the surface of liposomes, and the effects of modification are not marked enough. In this study, we examined the fixed aqueous layer t
Autor:
S Matsuo, Atsuo Miyagishima, Takashi Sonobe, Sadao Hirota, K Shimada, Yasuyuki Sadzuka, Yasuo Nozawa
Publikováno v:
International Journal of Pharmaceutics. 203:255-263
We describe a method for determining incorporated amounts of poly(ethylene glycol) (PEG)-derivatized lipids in liposomes for the physicochemical characterization of PEG-coated liposomes. This method is based on the spectrophotometric determination of