Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Atsuo Kawahara"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Krüppel-like transcription factors (Klfs), which are characterized by the three conserved C-terminal zinc fingers, are involved in various biological processes, such as haematopoiesis and angiogenesis. However, how the Klf family of transcr
Externí odkaz:
https://doaj.org/article/027881cd15794b13b0d40b04dc8c194c
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Trrap (transformation/transcription domain-associated protein) is a component shared by several histone acetyltransferase (HAT) complexes and participates in transcriptional regulation and DNA repair; however, the developmental functions of
Externí odkaz:
https://doaj.org/article/1e1b743555dd4bae96cf552270588ae3
Autor:
Ryo Iwasaki, Kyoshiro Tsuge, Koichiro Kishimoto, Yuta Hayashi, Takuya Iwaana, Hirofumi Hohjoh, Tomoaki Inazumi, Atsuo Kawahara, Soken Tsuchiya, Yukihiko Sugimoto
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Lymphatic endothelial cells arise from the venous endothelial cells in embryonic lymphatic development. However, the molecular mechanisms remain to be elucidated. We here report that prostaglandin (PG) E2 plays essential roles in the embryon
Externí odkaz:
https://doaj.org/article/b4f00d0dbb1c4106b21bf77585765da8
Autor:
Vu Thanh Nguyen, Lixuan Bian, Junya Tamaoki, Shiro Otsubo, Masafumi Muratani, Atsuo Kawahara, Makoto Kobayashi
Publikováno v:
Redox Biology, Vol 36, Iss , Pp 101667- (2020)
The Keap1–Nrf2 pathway is an evolutionarily conserved mechanism that protects cells from oxidative stress and electrophiles. Under homeostatic conditions, Keap1 interacts with Nrf2 and leads to its rapid proteasomal degradation, but when cells are
Externí odkaz:
https://doaj.org/article/5dd5559339e84a2aa4e6901160c6bb39
Publikováno v:
Biology Open, Vol 4, Iss 11, Pp 1576-1582 (2015)
The Mindbomb E3 ubiquitin protein ligase (Mib) family of proteins, Mib1 and Mib2, are RING finger ubiquitin ligases that share specific substrates. Mib1 is known to play essential roles in Notch signalling by ubiquitinating Notch ligands in vivo. Con
Externí odkaz:
https://doaj.org/article/bf120b25c13341a0b3bce299d661e8b6
Publikováno v:
Biology Open, Vol 2, Iss 8, Pp 789-794 (2013)
Summary The lipid mediator sphingosine-1-phosphate (S1P) is a regulator of cardiac development in zebrafish, as disruption of its receptor s1pr2 or transporter spns2 causes migration defects in cardiac progenitors. To examine the genetic interaction
Externí odkaz:
https://doaj.org/article/683dbe1a25c84333b82094d3b2c0fd27
Autor:
Yu Hisano, Satoshi Ota, Kazuharu Arakawa, Michiko Muraki, Nobuaki Kono, Kazuki Oshita, Tetsushi Sakuma, Masaru Tomita, Takashi Yamamoto, Yasushi Okada, Atsuo Kawahara
Publikováno v:
Biology Open, Vol 2, Iss 4, Pp 363-367 (2013)
Summary Artificially designed nucleases such as zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs) can induce a targeted DNA double-strand break at the specific target genomic locus, leading to the frameshift-me
Externí odkaz:
https://doaj.org/article/9b7f12afc71e402790efcd9b536b7ebd
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128319 (2015)
The type II clustered regularly interspaced short palindromic repeats (CRISPR) associated with Cas9 endonuclease (CRISPR/Cas9) has become a powerful genetic tool for understanding the function of a gene of interest. In zebrafish, the injection of Cas
Externí odkaz:
https://doaj.org/article/8c0f820320244d0abe387d16702d4bc5
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 5, p 727 (2016)
The zebrafish (Danio rerio) is an ideal vertebrate model to investigate the developmental molecular mechanism of organogenesis and regeneration. Recent innovation in genome editing technologies, such as zinc finger nucleases (ZFNs), transcription act
Externí odkaz:
https://doaj.org/article/1ae40f84f24847b4b3f86d6a074037b1
Autor:
Yusuke Kamachi, Atsuo Kawahara
Publikováno v:
Methods in Molecular Biology ISBN: 9781071630150
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b311bc595d05a5961636991adde7ceab
https://doi.org/10.1007/978-1-0716-3016-7_24
https://doi.org/10.1007/978-1-0716-3016-7_24
