Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Atsuko Yonemura"'
Autor:
Xichen Hu, Tadahito Yasuda, Noriko Yasuda-Yosihara, Atsuko Yonemura, Terumasa Umemoto, Yutaka Nakachi, Kohei Yamashita, Takashi Semba, Kota Arima, Tomoyuki Uchihara, Akiho Nishimura, Luke Bu, Lingfeng Fu, Feng Wei, Jun Zhang, Yilin Tong, Huaitao Wang, Kazuya Iwamoto, Takaichi Fukuda, Hayato Nakagawa, Koji Taniguchi, Yuji Miyamoto, Hideo Baba, Takatsugu Ishimoto
Publikováno v:
JHEP Reports, Vol 5, Iss 12, Pp 100892- (2023)
Background & Aims: Hepatocellular carcinoma (HCC) mainly develops from chronic hepatitis. Metabolic dysfunction-associated steatohepatitis (MASH) has gradually become the main pathogenic factor for HCC given the rising incidence of obesity and metabo
Externí odkaz:
https://doaj.org/article/866d6ebc777d4913969a931bf6ca5488
Autor:
Fumimasa Kitamura, Takashi Semba, Noriko Yasuda-Yoshihara, Kosuke Yamada, Akiho Nishimura, Juntaro Yamasaki, Osamu Nagano, Tadahito Yasuda, Atsuko Yonemura, Yilin Tong, Huaitao Wang, Takahiko Akiyama, Kazuki Matsumura, Norio Uemura, Rumi Itoyama, Luke Bu, Lingfeng Fu, Xichen Hu, Feng Wei, Kosuke Mima, Katsunori Imai, Hiromitsu Hayashi, Yo-ichi Yamashita, Yuji Miyamoto, Hideo Baba, Takatsugu Ishimoto
Publikováno v:
JCI Insight, Vol 8, Iss 20 (2023)
Glycolysis is highly enhanced in pancreatic ductal adenocarcinoma (PDAC) cells; thus, glucose restrictions are imposed on nontumor cells in the PDAC tumor microenvironment (TME). However, little is known about how such glucose competition alters meta
Externí odkaz:
https://doaj.org/article/f3cb47775802480a848b7f0f3290f90a
Autor:
Tadahito Yasuda, Mayu Koiwa, Atsuko Yonemura, Takahiko Akiyama, Hideo Baba, Takatsugu Ishimoto
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100553- (2021)
Summary: Accumulating evidence suggests that the malignant behavior of cancer is influenced by stromal activity in the tumor microenvironment. Cancer-associated fibroblasts (CAFs), which are the main component of the cancerous stroma, play an importa
Externí odkaz:
https://doaj.org/article/f8c7bb9689644ed39857ed8cd0db5d07
Autor:
Tadahito Yasuda, Mayu Koiwa, Atsuko Yonemura, Keisuke Miyake, Ryusho Kariya, Sho Kubota, Takako Yokomizo-Nakano, Noriko Yasuda-Yoshihara, Tomoyuki Uchihara, Rumi Itoyama, Luke Bu, Lingfeng Fu, Kota Arima, Daisuke Izumi, Shiro Iwagami, Kojiro Eto, Masaaki Iwatsuki, Yoshifumi Baba, Naoya Yoshida, Hiroto Ohguchi, Seiji Okada, Keisuke Matsusaki, Goro Sashida, Akiko Takahashi, Patrick Tan, Hideo Baba, Takatsugu Ishimoto
Publikováno v:
Cell Reports, Vol 34, Iss 8, Pp 108779- (2021)
Summary: In the tumor microenvironment, senescent non-malignant cells, including cancer-associated fibroblasts (CAFs), exhibit a secretory profile under stress conditions; this senescence-associated secretory phenotype (SASP) leads to cancer progress
Externí odkaz:
https://doaj.org/article/3ca48152ebfc477bbbd863180a470749
Autor:
Feng Wei, Tomoyuki Uchihara, Atsuko Yonemura, Noriko Yasuda‐Yoshihara, Tadahito Yasuda, Takashi Semba, Masahiro Fukuda, Takahiko Akiyama, Fumimasa Kitamura, Luke Bu, Xichen Hu, Lingfeng Fu, Jun Zhang, Ryusho Kariya, Juntaro Yamasaki, Kazuki Aihara, Kohei Yamashita, Osamu Nagano, Seiji Okada, Hideo Baba, Takatsugu Ishimoto
Publikováno v:
The FEBS Journal. 290:2604-2615
Fibroblast activation protein (FAP) generally shows low or undetectable expression in most normal tissues but is highly expressed in fibroblasts in almost all carcinomas. FAP is one of the potential molecules to detect activated fibroblasts and has m
Autor:
Takahiko Akiyama, Tadahito Yasuda, Tomoyuki Uchihara, Noriko Yasuda-Yoshihara, Benjy J.Y. Tan, Atsuko Yonemura, Takashi Semba, Juntaro Yamasaki, Yoshihiro Komohara, Koji Ohnishi, Feng Wei, Lingfeng Fu, Jun Zhang, Fumimasa Kitamura, Kohei Yamashita, Kojiro Eto, Shiro Iwagami, Hirotake Tsukamoto, Terumasa Umemoto, Mari Masuda, Osamu Nagano, Yorifumi Satou, Hideyuki Saya, Patrick Tan, Hideo Baba, Takatsugu Ishimoto
Publikováno v:
Cancer Research. 83:753-770
Excess stroma and cancer-associated fibroblasts (CAF) enhance cancer progression and facilitate immune evasion. Insights into the mechanisms by which the stroma manipulates the immune microenvironment could help improve cancer treatment. Here, we aim
Autor:
Takatsugu Ishimoto, Hideo Baba, Patrick Tan, Jaffer A. Ajani, Mari Masuda, Masakazu Yashiro, Naoya Yoshida, Yoshifumi Baba, Shiro Iwagami, Masaaki Iwatsuki, Hiromitsu Hayashi, Kojiro Eto, Kazuto Harada, Kota Arima, Tadahito Yasuda, Mayu Koiwa, Rumi Itoyama, Yoshihiro Komohara, Atsuko Yonemura, Keisuke Miyake, Tomoyuki Uchihara
Extracellular vesicles (EV) from cancer-associated fibroblasts (CAF) are composed of diverse payloads. Although CAFs impact the aggressive characteristics of gastric cancer cells, the contribution of CAF-EV to gastric cancer progression has not been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b84d7e0feb4d6a8fe43bfe01a1b6fb
https://doi.org/10.1158/0008-5472.c.6511711
https://doi.org/10.1158/0008-5472.c.6511711
Autor:
Takatsugu Ishimoto, Hideo Baba, Patrick Tan, Hideyuki Saya, Yorifumi Satou, Osamu Nagano, Mari Masuda, Terumasa Umemoto, Hirotake Tsukamoto, Shiro Iwagami, Kojiro Eto, Kohei Yamashita, Fumimasa Kitamura, Jun Zhang, Lingfeng Fu, Feng Wei, Koji Ohnishi, Yoshihiro Komohara, Juntaro Yamasaki, Takashi Semba, Atsuko Yonemura, Benjy J.Y. Tan, Noriko Yasuda-Yoshihara, Tomoyuki Uchihara, Tadahito Yasuda, Takahiko Akiyama
Supplementary Figure8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16896bbdd7fc47b212f99b19dcc3ac66
https://doi.org/10.1158/0008-5472.22433277.v1
https://doi.org/10.1158/0008-5472.22433277.v1
Autor:
Takatsugu Ishimoto, Hideo Baba, Patrick Tan, Jaffer A. Ajani, Mari Masuda, Masakazu Yashiro, Naoya Yoshida, Yoshifumi Baba, Shiro Iwagami, Masaaki Iwatsuki, Hiromitsu Hayashi, Kojiro Eto, Kazuto Harada, Kota Arima, Tadahito Yasuda, Mayu Koiwa, Rumi Itoyama, Yoshihiro Komohara, Atsuko Yonemura, Keisuke Miyake, Tomoyuki Uchihara
Real-time imaging of AGS cells treated with CAF-CM in the ECM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f685c1ca066d4e558e7a30b914bb038
https://doi.org/10.1158/0008-5472.22424203
https://doi.org/10.1158/0008-5472.22424203
Autor:
Takatsugu Ishimoto, Hideo Baba, Patrick Tan, Jaffer A. Ajani, Mari Masuda, Masakazu Yashiro, Naoya Yoshida, Yoshifumi Baba, Shiro Iwagami, Masaaki Iwatsuki, Hiromitsu Hayashi, Kojiro Eto, Kazuto Harada, Kota Arima, Tadahito Yasuda, Mayu Koiwa, Rumi Itoyama, Yoshihiro Komohara, Atsuko Yonemura, Keisuke Miyake, Tomoyuki Uchihara
Real-time imaging of AGS cells treated with normal medium in the ECM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a56ec326ab98f5cabc0a11869e9d774
https://doi.org/10.1158/0008-5472.22424206
https://doi.org/10.1158/0008-5472.22424206