Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Atsuko Miura"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6452 (2024)
It has been reported that Mizoribine is an immunosuppressant used to suppress rejection in renal transplantation, nephrotic syndrome, lupus nephritis, and rheumatoid arthritis. The molecular chaperone HSP60 alone induces inflammatory cytokine IL-6 an
Externí odkaz:
https://doaj.org/article/0f8e6313475b43d285af7c621dfffbfe
Autor:
Yukihiko Narita, Arisa Tamura, Shiori Hatakeyama, Seiya Uemura, Atsuko Miura, Asami Haga, Noriko Tsuji, Nozomi Fujie, Yukina Izumi, Taku Sugawara, Michiro Otaka, Ken Okamoto, Peng Lu, Suguru Okuda, Michio Suzuki, Koji Nagata, Hiroaki Shimizu, Hideaki Itoh
Publikováno v:
FEBS Letters; Jun2024, Vol. 598 Issue 12, p1478-1490, 13p
Publikováno v:
RSC Advances. 9:40368-40377
Annonaceous acetogenins have a wide range of potential biological activities. The development of simple and diversity-oriented approaches to their synthesis is therefore important. We have achieved the first total synthesis of squafosacin F and assig
Autor:
Yusuke Kawai, Miya Hamamoto, Mayumi Yamaguchi, Maiko Iwata, Yuko Ikematsu, Yukari Masuda, Miki Kanbe, Atsuko Miura
Publikováno v:
Internal and emergency medicine. 17(1)
Physical restraint is widely used in the intensive care unit (ICU) to ensure patient safety despite its ethical implications. We performed a prospective observational study in six ICUs in Japan to determine the prevalence of and factors associated wi
Publikováno v:
Organic & Biomolecular Chemistry. 16:3018-3025
A divergent strategy has been used for the concise and efficient enantioselective formal synthesis of Annonaceous acetogenin cis-solamin. Our synthetic strategy comprises concise preparation of the diepoxyester via an 11-membered silaketal constructe
Autor:
Teturou Satoh, Emi Ishida, Masatomo Mori, Nobuyuki Shibusawa, Atsuko Miura, Atsushi Ozawa, Koshi Hashimoto, Masanobu Yamada, Shuichi Okada
Publikováno v:
Endocrinology. 154:537-549
Stearoyl-CoA desaturase-1 (SCD-1) plays a pivotal role in an increase of triglyceride by an excess of dietary carbohydrate intake. Dietary carbohydrates increase SCD-1 gene expression in liver by sterol response element binding protein (SREBP)-1c-dep
Autor:
Yuko Tagaya, Shuichi Okada, Koshi Hashimoto, Tetsurou Satoh, Aya Osaki, Hiroyuki Shimizu, Masatomo Mori, Atsuko Miura, Kihachi Ohshima, Masanobu Yamada
Publikováno v:
Protein and Peptide Letters
Nucleobindin-2 is a 420 amino acid EF-hand Ca²⁺ binding protein that can be further processed to generate an 82 amino terminal peptide termed Nesfatin-1. To examine the function of secreted Nucleobindin-2 in adipocyte differentiation, cultured 3T3
Autor:
Shozo Yamada, Atsushi Ozawa, Nobuyuki Shibusawa, Kazuhiko Horiguchi, Shunichi Matsumoto, Teturou Satoh, Masanobu Yamada, Koshi Hashimoto, Atsuko Miura, Masatomo Mori, Emi Ishida
Publikováno v:
Neuroscience Letters. 494:34-37
The liver X receptors (LXR-α and -β) are nuclear oxysterol receptors that play pivotal roles in regulating the expression of genes involved in cholesterol transport and metabolism. Recently, several groups have reported that the LXRs also regulate
Autor:
Masanobu Yamada, Atsuko Miura, Tetsurou Satoh, Koshi Hashimoto, Masatomo Mori, Emi Ishida, Atsushi Ozawa, Shuichi Okada, Nobuyuki Shibusawa
Publikováno v:
Biochemical and Biophysical Research Communications. 394:548-552
We have recently reported that an alternative splicing variant of liver X receptor (LXR)-beta acts as an RNA co-activator, which is referred to as LXRBSV. The in vivo role of LXRBSV is yet to be clarified. The LXRBSV gene is expressed in various tiss
Autor:
Mark A. Magnuson, Frances M. Sladek, Haruo Kasai, Hiroyasu Hatakeyama, Iichiro Shimomura, Atsuko Miura, Takao Nammo, Noriko Takahashi, Yusuke Inoue, Kenji Fukui, Kazue Yoneda, Frank J. Gonzalez, Masafumi Kakei, Jun-ichiro Miyagawa, Kazuya Yamagata
Publikováno v:
Journal of Biological Chemistry. 281:5246-5257
Mutations in the hepatocyte nuclear factor (HNF)-4alpha gene cause a form of maturity-onset diabetes of the young (MODY1) that is characterized by impairment of glucose-stimulated insulin secretion by pancreatic beta-cells. HNF-4alpha, a transcriptio