Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Atsuko Kita"'
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 33:1040-1045
AC-5216, a ligand for the translocator protein (18 kDa) (TSPO), produces anxiolytic-like effects in animal models of anxiety without causing the side effects normally associated with conventional benzodiazepines. This study aimed to investigate wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78785096d8ec7b4f5ccad70ef71bf287
https://doi.org/10.1016/j.pnpbp.2009.05.018
https://doi.org/10.1016/j.pnpbp.2009.05.018
Autor:
Makoto Oka, Tomoko Kinoshita, Kiyoshi Furukawa, Keiko Nakamichi, Hitoshi Kohayakawa, Atsuko Kita, Yoshiaki Ochi, Kurumiya Satoshi
Publikováno v:
British Journal of Pharmacology. 142:1059-1072
We investigated the ability of N-benzyl-N-ethyl-2-(7,8-dihydro-7-methyl-8-oxo-2-phenyl-9H-purin-9-yl)acetamide (AC-5216), a novel mitochondrial benzodiazepine receptor (MBR) ligand, to produce anti-anxiety and antidepressant-like effects in various a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb409ed8a9ebe77280e5a07979b84a84
https://doi.org/10.1038/sj.bjp.0705681
https://doi.org/10.1038/sj.bjp.0705681
Publikováno v:
European Journal of Pharmacology. 237:317-322
Recombinant human interleukin-1 alpha (rHu-IL-1 alpha) has been indicated to produce central antinociception in the mouse phenylquinone writhing test, the antinociception being unaffected by naloxone. Because interleukin-1 has been demonstrated to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2cc9d28de44cf0e26845ab67c0ddd7
https://doi.org/10.1016/0014-2999(93)90284-o
https://doi.org/10.1016/0014-2999(93)90284-o
Autor:
Ikuhisa Yakuo, Kiyomi Imano, Hideo Nakamura, Katsuya Seguro, Atsuko Kita, Yasuo Ariyoshi, Noriki Nio
Publikováno v:
FEBS Letters. 319:225-228
To delineate the binding site in the human immunoglobulin E (IgE) molecule to the Fc epsilon receptor on basophils and mast cells, we chemically synthesized a total of 71 peptide fragments within the sequence Ser300-Lys547 in the human IgE molecule.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a652bd1d67a3e3fd1950e8192ba69bd0
https://doi.org/10.1016/0014-5793(93)80551-5
https://doi.org/10.1016/0014-5793(93)80551-5
Autor:
Junji Konishi, Hideo Nakamura, Satoshi Iimuma, Tsutomu Mimoto, Hideo Saji, Atsuko Kita, Akira Yokoyama, Yoshiaki Kiso, Daisuke Tsutsumi, Kenichi Akaji, Yasuhiro Magata
Publikováno v:
International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology. 19:455-460
The 13N-labeled opioid tetrapeptide, Tyr-D-Met(O)-Phe-Gly-[13N]NH2 (SD-62), was synthesized by amidation of its activated p-nitrophenol ester with [13N]ammonia (total synthesis time: 25 min, radiochemical yield: 48%). When injected intravenously into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eea87c1dc66c6dc89025286bc003138
https://doi.org/10.1016/0883-2897(92)90160-z
https://doi.org/10.1016/0883-2897(92)90160-z
Publikováno v:
YAKUGAKU ZASSHI. 110:349-353
Analgesic activity of morphine administered rectally as a suppository was investigated in rats in order to ascertain analgesic activity of morphine suppository. Morphine hydrochloride given rectally as a suppository produced analgesic activity in a d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6135a0c896b1f354c5cdbe51ef4a4125
https://doi.org/10.1248/yakushi1947.110.5_349
https://doi.org/10.1248/yakushi1947.110.5_349
Autor:
Atsuko Kita, Kiyoshi Furukawa
Publikováno v:
Pharmacology, biochemistry, and behavior. 89(2)
AC-5216, a ligand for the translocator protein (18 kDa) (TSPO), previously called the peripheral benzodiazepine receptor (PBR), produces anxiolytic-like effects mediated by TSPO in animal models of anxiety. Since stimulation of TSPO is considered to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c87678d96202d49bb8dc807596b4b9d0
https://pubmed.ncbi.nlm.nih.gov/18201755
https://pubmed.ncbi.nlm.nih.gov/18201755
Autor:
Atsuko, Kita, Hitoshi, Kohayakawa, Tomoko, Kinoshita, Yoshiaki, Ochi, Keiko, Nakamichi, Satoshi, Kurumiya, Kiyoshi, Furukawa, Makoto, Oka
Publikováno v:
British journal of pharmacology. 142(7)
We investigated the ability of N-benzyl-N-ethyl-2-(7,8-dihydro-7-methyl-8-oxo-2-phenyl-9H-purin-9-yl)acetamide (AC-5216), a novel mitochondrial benzodiazepine receptor (MBR) ligand, to produce anti-anxiety and antidepressant-like effects in various a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa572b3b4d0474c41c8754ab3c6fd6de
https://pubmed.ncbi.nlm.nih.gov/15249420
https://pubmed.ncbi.nlm.nih.gov/15249420
Autor:
Motohiro Takahashi, Lawrence H. Lazarus, Yusuke Sasaki, Sharon D. Bryant, Tingyou Li, Toshio Yokoi, Yunden Jinsmaa, Atsuko Kita, Takashi Motoyama, Yoshio Fujita, Yoshiro Shimizu, Akihiro Ambo, Yuko Tsuda, Yoshio Okada
Publikováno v:
Journal of medicinal chemistry. 47(14)
The C terminus of endomorphin-2 (EM-2) analogues (Tyr-Pro-Phe-NH-X) was modified with aromatic, heteroaromatic, or aliphatic groups (X = phenethyl,benzyl, phenyl, naphthyl, pyridyl, quinolyl, isoquinolyl, tert-butyl, cyclohexyl, or adamantyl; 3-18) t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965dbfc5fb76f2bdb39b15ccb6bd920b
https://pubmed.ncbi.nlm.nih.gov/15214786
https://pubmed.ncbi.nlm.nih.gov/15214786
Autor:
Makoto Kodaira, Kan Yonemori, Tatsunori Shimoi, Akihiko Yoshida, Masayuki Yoshida, Atsuko Kitano, Akihiko Shimomura, Mayu Yunokawa, Chikako Shimizu, Yuichi Takiguchi, Yasuhiro Fujiwara, Kenji Tamura
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background The clinical utility and prognostic impact of presumed primary breast or ovarian cancer among patients with an unfavorable subset of cancer of unknown primary site (CUP) remains unclear. We aimed to evaluate the clinical relevance
Externí odkaz:
https://doaj.org/article/74e348b9d5a3407c9f6b9d841f1e1b03