Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Atsuko Asano"'
Autor:
Hirotake Furihata, Satoshi Yamanaka, Toshiaki Honda, Yumiko Miyauchi, Atsuko Asano, Norio Shibata, Masaru Tanokura, Tatsuya Sawasaki, Takuya Miyakawa
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
5-hydroxythalidomide is a primary thalidomide metabolite generated by the cytochrome P450 isozymes. The reported data, including crystal structure of the 5-hydroxythalidomide-mediated complex of CRBN with SALL4, elucidate how additional hydroxy group
Externí odkaz:
https://doaj.org/article/e6839866ce1b4a9fbf178c9bea0007d2
Autor:
Toshiaki Honda, Tatsuya Sawasaki, Satoshi Yamanaka, Masaru Tanokura, Takuya Miyakawa, Hirotake Furihata, Norio Shibata, Yumiko Miyauchi, Atsuko Asano
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
Thalidomide and its derivatives exert not only therapeutic effects as immunomodulatory drugs (IMiDs) but also adverse effects such as teratogenicity, which are due in part to different C2H2 zinc-finger (ZF) transcription factors, IKZF1 (or IKZF3) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6439327212c52c7c5a3f3b0f4e33146b
https://doi.org/10.1038/s41467-020-18488-4
https://doi.org/10.1038/s41467-020-18488-4
Autor:
Akinori Okumura, Takuya Miyakawa, Satoshi Yamagoe, Yoriko Sawano, Atsuko Asano, Hai Zheng, Masaru Tanokura
Publikováno v:
Journal of Biological Chemistry. 291:17133-17142
Human leukocyte cell-derived chemotaxin 2 (LECT2), which is predominantly expressed in the liver, is a multifunctional protein. LECT2 is becoming a potential therapeutic target for several diseases of worldwide concern such as rheumatoid arthritis, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6d3b82c1892279e1c21d35c2023dd7
https://doi.org/10.1074/jbc.m116.720375
https://doi.org/10.1074/jbc.m116.720375
Autor:
Hui-Min Qin, Ryuji Nishiyama, Masaru Tanokura, Takao Ojima, Akira Inoue, Atsuko Asano, Akira Nakamura, Takuya Miyakawa
Publikováno v:
Chemical communications (Cambridge, England). 54(5)
FlAlyA is an endolytic enzyme with a preference for polymannuronate. The crystal structure and mutagenesis studies elucidated that the structural variations at outer uronate-binding subsites +2, +3 and -2 control the enzymatic properties of PL-7 fami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891c4f7308769c9d27f97c4fffa94c43
https://pubmed.ncbi.nlm.nih.gov/29292806
https://pubmed.ncbi.nlm.nih.gov/29292806
Publikováno v:
Protein Expression and Purification. 115:69-75
Secretory phospholipase A2 (sPLA2) catalyzes the hydrolysis of sn-2 linkage in the glycerophospholipid, thereby releasing fatty acid and 1-acyl lysophospholipid. Among sPLA2s from various organisms and tissues, group XIV fungal/bacterial sPLA2s are r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f77ae82588f1c35d024fee6a77c483af
https://doi.org/10.1016/j.pep.2015.08.007
https://doi.org/10.1016/j.pep.2015.08.007
Autor:
Yasunari Fujita, Masaru Tanokura, Ken-Suke Kodaira, Yuehua Zhi, Atsuko Asano, Takuya Miyakawa, Mihoko Takahashi, Ken-ichi Miyazono, Yumiko Miyauchi, Takuya Yoshida, Kazuko Yamaguchi-Shinozaki, Yoriko Sawano, Hee-Jin Kang, Keiko Kubota
Publikováno v:
Nature. 462:609-614
The phytohormone abscisic acid (ABA) mediates the adaptation of plants to environmental stresses such as drought and regulates developmental signals such as seed maturation. Within plants, the PYR/PYL/RCAR family of START proteins receives ABA to inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0147673f9f78850780a11ecaeee6b2e0
https://doi.org/10.1038/nature08583
https://doi.org/10.1038/nature08583
Autor:
Ayumi, Takayanagi, Takuya, Miyakawa, Atsuko, Asano, Jun, Ohtsuka, Masaru, Tanokura, Manabu, Arioka
Publikováno v:
Protein expression and purification. 115
Secretory phospholipase A2 (sPLA2) catalyzes the hydrolysis of sn-2 linkage in the glycerophospholipid, thereby releasing fatty acid and 1-acyl lysophospholipid. Among sPLA2s from various organisms and tissues, group XIV fungal/bacterial sPLA2s are r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fcbf916a8560ebd3849b86a007284113
https://pubmed.ncbi.nlm.nih.gov/26272369
https://pubmed.ncbi.nlm.nih.gov/26272369
Autor:
Atsuko Asano, Hiroyuki Aoyagi, Mitsunori Yamada, Iku Utsunomiya, Toshio Ariga, Hiide Yoshino, Kyoji Taguchi, Takumi Nagaoka, Tadashi Miyatake
Publikováno v:
Brain Research. 1057:177-180
We investigated the localization of GalNAc-GD1a biochemically in the human and bovine peripheral nervous system (PNS). The high-performance thin-layer chromatography (HPTLC)-overlay method with rabbit IgG polyclonal antibody against GalNAc-GD1a (anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191c3402d6382eecd6eb0cb85fc9b247
https://doi.org/10.1016/j.brainres.2005.07.063
https://doi.org/10.1016/j.brainres.2005.07.063
Autor:
Toshio Matsumoto, Atsuko Asano, Miho Tsuruo, Makoto Kunishige, Takao Mitsui, Hiide Yoshino, Fumikazu Yagi, Itsuro Endo
Publikováno v:
Journal of the Neurological Sciences. 225:51-55
We describe seven patients with isolated cranial neuropathy in whom serum anti-glycolipid antibodies were detected. Trigeminal sensory neuropathy was found in four patients, who had exhibited symptoms for 2 months to 4 years. The other three patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d7d542e8df5c987978037b7a1f4e37
https://doi.org/10.1016/j.jns.2004.06.017
https://doi.org/10.1016/j.jns.2004.06.017
Autor:
Toshio Matsumoto, Yasushi Oshima, Hiide Yoshino, Atsuko Asano, Makoto Kunishige, Takao Mitsui, I Endo
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 73:568-573
Objectives: Several serum antibodies against gangliosides are diagnostically important, particularly in Guillain-Barre syndrome (GBS), Miller Fisher syndrome (MFS), and multifocal motor neuropathy (MMN). Although hyperreflexia is an atypical symptom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3645c3278737e7c8728bc84dd45e9821
https://doi.org/10.1136/jnnp.73.5.568
https://doi.org/10.1136/jnnp.73.5.568