Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Atsuhito Tanuma"'
Autor:
Hiroyoshi Sato, Ryohei Kaseda, Akihiko Saito, Michihiro Hosojima, Hitomi Hama, Noriaki Iino, Tetsuro Takeda, Hiroaki Obayashi, Kiyoko Hosaka, Mitsuhiro Ueno, Fumitake Gejyo, Atsuhito Tanuma, Kenji Sakimura, Naofumi Imai, Maya Yamazaki
Publikováno v:
Nephron Physiology. 107:p87-p97
Background/Aims: Mutations of the endosomal chloride/proton exchanger gene, CLCN5, cause Dent’s disease, an X-linked recessive proximal tubular disorder. The renal endocytic system was found to be affected in clcn5 knockout mice. However, the impai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e7b88da64b64e8a26df2c252f872c15
https://doi.org/10.1159/000111253
https://doi.org/10.1159/000111253
Autor:
Maya Yamazaki, Hitomi Hama, Ryohei Kaseda, Tetsuro Takeda, Fumitake Gejyo, Michihiro Hosojima, Hiroaki Obayashi, Kenji Sakimura, Naofumi Imai, Hiroyoshi Sato, Mitsuhiro Ueno, Noriaki Iino, Kiyoko Hosaka, Akihiko Saito, Atsuhito Tanuma
Publikováno v:
Nephron Physiology. 107:I-V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1f3f23d3a594baa0d3e2e06745b543b
https://doi.org/10.1159/000113386
https://doi.org/10.1159/000113386
Autor:
Shinya Ogasawara, Yuko Oyama, Shinichi Nishi, Akihiko Saito, Fumio Gondaira, Yoshiki Suzuki, Hitomi Hama, Kiyoko Hosaka, Atsuhito Tanuma, Fumitake Gejyo, Mitsuhiro Ueno, Ryohei Kaseda, Tetsuro Takeda
Publikováno v:
Nephrology. 10:S26-S31
Megalin is an endocytic receptor on the apical membranes of proximal tubule cells (PTC) in the kidney, and is involved in the reabsorption and metabolism of various proteins that have been filtered by glomeruli. Patients with diabetes, especially typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d1a5897de6b77df5c05d5df365fc86
https://doi.org/10.1111/j.1440-1797.2005.00453.x
https://doi.org/10.1111/j.1440-1797.2005.00453.x
Autor:
Hiroshi Fujii, Noriaki Iino, Kunihiro Mizuta, Meilei Ma, Yoshio Terada, Tetsuro Takeda, Akihiko Saito, Hitomi Hama, Atsuhito Tanuma, Shoji Odani, Tadashi Yamamoto, Kiyoko Sato, Yuko Oyama, Fumitake Gejyo, Junichiro James Kazama, Ryohei Kaseda
Publikováno v:
Laboratory Investigation. 85:522-531
Liver-type fatty acid binding protein (L-FABP) binds with high affinity to hydrophobic molecules including free fatty acid, bile acid and bilirubin, which are potentially nephrotoxic, and is involved in their metabolism mainly in hepatocytes. L-FABP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b92cbd6e1d9f0042697447025c92ebd
https://doi.org/10.1038/labinvest.3700240
https://doi.org/10.1038/labinvest.3700240
Autor:
Junichiro James Kazama, Hitomi Hama, Yuansheng Xie, Tetsuro Takeda, Atsuhito Tanuma, Kiyoko Sato, Akihiko Saito, Fumitake Gejyo
Publikováno v:
Endocrinology. 145:3935-3940
Leptin is secreted by adipocytes and is a circulating factor that regulates food intake and energy expenditure. Its serum level is elevated in patients with renal failure and has been suggested to be associated with malnutritional factors in these pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518507d69e5065f537a1be3c0f03b231
https://doi.org/10.1210/en.2004-0074
https://doi.org/10.1210/en.2004-0074
Autor:
Seikoh Horiuchi, Fumitake Gejyo, Hitomi Hama, Tetsuro Takeda, Yutaka Yoshida, Tosifusa Toda, Ryoji Nagai, Akihiko Saito, Atsuhito Tanuma, Kenji Cho, Fujio Shimizu
Publikováno v:
Journal of the American Society of Nephrology. 14:1123-1131
Advanced glycation end products (AGE) are filtered by glomeruli and reabsorbed and metabolized by proximal tubule cells (PTC). In renal failure, decreased renal AGE metabolism likely accounts for the accumulation in serum that is related to uremic co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a1962b55d263460e60d6e9a7664843
https://doi.org/10.1097/01.asn.0000062962.51879.f8
https://doi.org/10.1097/01.asn.0000062962.51879.f8
Autor:
Atsuhito, Tanuma, Hiroyoshi, Sato, Tetsuro, Takeda, Michihiro, Hosojima, Hiroaki, Obayashi, Hitomi, Hama, Noriaki, Iino, Kiyoko, Hosaka, Ryohei, Kaseda, Naofumi, Imai, Mitsuhiro, Ueno, Maya, Yamazaki, Kenji, Sakimura, Fumitake, Gejyo, Akihiko, Saito
Publikováno v:
Nephron. Physiology. 107(4)
Mutations of the endosomal chloride/proton exchanger gene, CLCN5, cause Dent's disease, an X-linked recessive proximal tubular disorder. The renal endocytic system was found to be affected in clcn5 knockout mice. However, the impaired endocytic machi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7713a387a42a04efc6a346cb14832ccf
https://pubmed.ncbi.nlm.nih.gov/18025833
https://pubmed.ncbi.nlm.nih.gov/18025833
Autor:
Ryohei Kaseda, Tetsuro Takeda, Akihiko Saito, Atsuhito Tanuma, Yoshiki Suzuki, Fumitake Gejyo, Kiyoko Sato, Hitomi Hama
Publikováno v:
Annals of the New York Academy of Sciences. 1043
Advanced glycation end products (AGEs) are formed by the nonenzymatic Maillard reaction between sugars and proteins. Low-molecular weight AGEs are filtered by renal glomeruli and then reabsorbed and metabolized by proximal tubule cells (PTCs). High-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c25b58c607844119ec8cd0202cf13a8
https://pubmed.ncbi.nlm.nih.gov/16037287
https://pubmed.ncbi.nlm.nih.gov/16037287