Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Atsuhiro Tomita"'
Autor:
Haon Futamata, Masahiro Fukuda, Rie Umeda, Keitaro Yamashita, Atsuhiro Tomita, Satoe Takahashi, Takafumi Shikakura, Shigehiko Hayashi, Tsukasa Kusakizako, Tomohiro Nishizawa, Kazuaki Homma, Osamu Nureki
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Outer hair cell electromotility, driven by prestin, is essential for mammalian cochlear amplification. Here, the authors report the cryo-EM structures of thermostabilized prestin in the presence of various anions, providing insight into the mechanism
Externí odkaz:
https://doaj.org/article/6182e337cf2c473db9846eed713f4e1b
Autor:
Haon Futamata, Masahiro Fukuda, Rie Umeda, Keitaro Yamashita, Atsuhiro Tomita, Satoe Takahashi, Takafumi Shikakura, Shigehiko Hayashi, Tsukasa Kusakizako, Tomohiro Nishizawa, Kazuaki Homma, Osamu Nureki
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/d71b7bcb150f483abf5fc374ba82465f
Autor:
Fei Jin, Minxuan Sun, Takashi Fujii, Yurika Yamada, Jin Wang, Andrés D Maturana, Miki Wada, Shichen Su, Jinbiao Ma, Hironori Takeda, Tsukasa Kusakizako, Atsuhiro Tomita, Yoshiko Nakada-Nakura, Kehong Liu, Tomoko Uemura, Yayoi Nomura, Norimichi Nomura, Koichi Ito, Osamu Nureki, Keiichi Namba, So Iwata, Ye Yu, Motoyuki Hattori
Publikováno v:
PLoS Biology, Vol 19, Iss 4, p e3001231 (2021)
MgtE is a Mg2+ channel conserved in organisms ranging from prokaryotes to eukaryotes, including humans, and plays an important role in Mg2+ homeostasis. The previously determined MgtE structures in the Mg2+-bound, closed-state, and structure-based fu
Externí odkaz:
https://doaj.org/article/1ea7be941cf6441f841a041603748098
Autor:
Kazumasa Oda, Takashi Nomura, Takanori Nakane, Keitaro Yamashita, Keiichi Inoue, Shota Ito, Johannes Vierock, Kunio Hirata, Andrés D Maturana, Kota Katayama, Tatsuya Ikuta, Itsuki Ishigami, Tamaki Izume, Rie Umeda, Ryuun Eguma, Satomi Oishi, Go Kasuya, Takafumi Kato, Tsukasa Kusakizako, Wataru Shihoya, Hiroto Shimada, Tomoyuki Takatsuji, Mizuki Takemoto, Reiya Taniguchi, Atsuhiro Tomita, Ryoki Nakamura, Masahiro Fukuda, Hirotake Miyauchi, Yongchan Lee, Eriko Nango, Rie Tanaka, Tomoyuki Tanaka, Michihiro Sugahara, Tetsunari Kimura, Tatsuro Shimamura, Takaaki Fujiwara, Yasuaki Yamanaka, Shigeki Owada, Yasumasa Joti, Kensuke Tono, Ryuichiro Ishitani, Shigehiko Hayashi, Hideki Kandori, Peter Hegemann, So Iwata, Minoru Kubo, Tomohiro Nishizawa, Osamu Nureki
Publikováno v:
eLife, Vol 10 (2021)
Channelrhodopsins (ChRs) are microbial light-gated ion channels utilized in optogenetics to control neural activity with light . Light absorption causes retinal chromophore isomerization and subsequent protein conformational changes visualized as opt
Externí odkaz:
https://doaj.org/article/bceebbada3ce47869ff14a50376a93f1
Autor:
Atsuhiro Tomita, Mingfeng Zhang, Fei Jin, Wenhui Zhuang, Hironori Takeda, Tatsuro Maruyama, Masanori Osawa, Ken-ichi Hashimoto, Hisashi Kawasaki, Koichi Ito, Naoshi Dohmae, Ryuichiro Ishitani, Ichio Shimada, Zhiqiang Yan, Motoyuki Hattori, Osamu Nureki
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Author summary MgtE is an Mg2+ transporter involved in Mg2+ homeostasis. Here, the authors report that ATP regulates the Mg+2-dependent gating of MgtE and use X-ray crystallography combined with functional studies to propose the molecular mechanisms
Externí odkaz:
https://doaj.org/article/f888e0a3dea7456dbdf43ae0cd85611d
Autor:
Atsuhiro TOMITA
Publikováno v:
Seibutsu Butsuri. 63:30-32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e0c30aaefce9b06ba8d580174251b3a
https://doi.org/10.2142/biophys.63.30
https://doi.org/10.2142/biophys.63.30
Autor:
Kazuhiro Kobayashi, Kouki Kawakami, Tsukasa Kusakizako, Hirotake Miyauchi, Atsuhiro Tomita, Kan Kobayashi, Wataru Shihoya, Keitaro Yamashita, Tomohiro Nishizawa, Hideaki E. Kato, Asuka Inoue, Osamu Nureki
Publikováno v:
Molecular Cell. 82:3468-3483.e5
Endogenous parathyroid hormone (PTH) and PTH-related peptide (PTHrP) bind to the parathyroid hormone receptor 1 (PTH1R) and activate the stimulatory G-protein (Gs) signaling pathway. Intriguingly, the two ligands have distinct signaling and physiolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a539baa74b1fd5c96ff044e0a9e2c38
https://doi.org/10.1016/j.molcel.2022.07.003
https://doi.org/10.1016/j.molcel.2022.07.003
Autor:
Nina Kurihara, Ryoya Nakagawa, Hisato Hirano, Sae Okazaki, Atsuhiro Tomita, Kan Kobayashi, Tsukasa Kusakizako, Tomohiro Nishizawa, Keitaro Yamashita, David A. Scott, Hiroshi Nishimasu, Osamu Nureki
Publikováno v:
Mol Cell
RNA-guided CRISPR-Cas nucleases are widely used as versatile genome-engineering tools. Recent studies identified functionally divergent type V Cas12 family enzymes. Among them, Cas12c2 binds a CRISPR RNA (crRNA) and a trans-activating crRNA (tracrRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ca28c6f3fbb7d19df80c7f5a5fadf88
https://pubmed.ncbi.nlm.nih.gov/35366394
https://pubmed.ncbi.nlm.nih.gov/35366394
Autor:
Tomoyuki Takatsuji, Tomoyuki Tanaka, Yasumasa Joti, Tomohiro Nishizawa, Satomi Oishi, Rie Umeda, Hiroto Shimada, Shigehiko Hayashi, Wataru Shihoya, Osamu Nureki, Rie Tanaka, Atsuhiro Tomita, Tetsunari Kimura, Peter Hegemann, Tatsuya Ikuta, Kunio Hirata, Takafumi Kato, Andrés D. Maturana, Kazumasa Oda, Yongchan Lee, Tamaki Izume, Reiya Taniguchi, Hideki Kandori, Masahiro Fukuda, Hirotake Miyauchi, Takashi Nomura, Kota Katayama, Keiichi Inoue, Minoru Kubo, Ryuun Eguma, So Iwata, Ryuichiro Ishitani, Keitaro Yamashita, Kensuke Tono, Eriko Nango, Takanori Nakane, Yasuaki Yamanaka, Ryoki Nakamura, Go Kasuya, Shota Ito, Shigeki Owada, Mizuki Takemoto, Tatsuro Shimamura, Tsukasa Kusakizako, Johannes Vierock, Michihiro Sugahara, Takaaki Fujiwara, Itsuki Ishigami
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Channelrhodopsins (ChRs) are microbial light-gated ion channels utilized in optogenetics to control neural activity with light . Light absorption causes retinal chromophore isomerization and subsequent protein conformational changes visualized as opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b932d284168d5e3e89a33e2bafcb26
https://elifesciences.org/articles/62389
https://elifesciences.org/articles/62389
Autor:
Takashi Fujii, Miki Wada, Jun-Song Wang, Yayoi Nomura, Andrés D. Maturana, Tsukasa Kusakizako, Yurika Yamada, So Iwata, Osamu Nureki, Yoshiko Nakada-Nakura, Atsuhiro Tomita, Motoyuki Hattori, Jie Ma, Keiichi Namba, Kei K. Ito, Minxuan Sun, H. Takeda, Fei Jin, Tomoko Uemura, Shichen Su, Norimichi Nomura, Ye Yu, Kehong Liu
MgtE is a Mg2+ channel conserved in organisms ranging from prokaryotes to eukaryotes, including humans, and plays an important role in Mg2+ homeostasis. The previously determined MgtE structures in the Mg2+-bound, closed state and structure-based fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cee246f6a6872896253039229e7be2e3
https://doi.org/10.1101/2020.08.27.270991
https://doi.org/10.1101/2020.08.27.270991
