Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Atsuhiro, Iimuro"'
Autor:
Takahiro Kawajiri, Akihito Kijima, Atsuhiro Iimuro, Eisaku Ohashi, Katsuya Yamakawa, Kazushi Agura, Kengo Masuda, Kensuke Kouki, Koji Kasamatsu, Shuichi Yanagisawa, Sho Nakashima, Setsuya Shibahara, Takashi Toyota, Takafumi Higuchi, Takahiro Suto, Tadashi Oohara, Toshikatsu Maki, Naoto Sahara, Nobuaki Fukui, Hisayuki Wakamori, Hidaka Ikemoto, Hiroaki Murakami, Hiroyasu Ando, Masahiro Hosoya, Mizuki Sato, Yusuke Suzuki, Yuta Nakagawa, Yuto Unoh, Yoichi Hirano, Yoshitomo Nagasawa, Satoshi Goda, Takafumi Ohara, Takayuki Tsuritani
Publikováno v:
ACS Central Science, Vol 9, Iss 4, Pp 836-843 (2023)
Externí odkaz:
https://doaj.org/article/9f38b46b1b194cdaac85377b26776798
Autor:
Eiichi Kojima, Atsuhiro Iimuro, Mado Nakajima, Hirotaka Kinuta, Naoya Asada, Yusuke Sako, Zenzaburo Nakata, Kentaro Uemura, Shuhei Arita, Shinobu Miki, Chiaki Wakasa-Morimoto, Yuki Tachibana
Publikováno v:
Journal of Medicinal Chemistry. 65:6157-6170
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47f9735709be42f4cf956b8442fd112d
https://doi.org/10.1021/acs.jmedchem.1c02217
https://doi.org/10.1021/acs.jmedchem.1c02217
Autor:
Takahiro Kawajiri, Akihito Kijima, Atsuhiro Iimuro, Eisaku Ohashi, Katsuya Yamakawa, Kazushi Agura, Kengo Masuda, Kensuke Kouki, Koji Kasamatsu, Shuichi Yanagisawa, Sho Nakashima, Setsuya Shibahara, Takashi Toyota, Takafumi Higuchi, Takahiro Suto, Tadashi Oohara, Toshikatsu Maki, Naoto Sahara, Nobuaki Fukui, Hisayuki Wakamori, Hidaka Ikemoto, Hiroaki Murakami, Hiroyasu Ando, Masahiro Hosoya, Mizuki Sato, Yusuke Suzuki, Yuta Nakagawa, Yuto Unoh, Yoichi Hirano, Yoshitomo Nagasawa, Satoshi Goda, Takafumi Ohara, Takayuki Tsuritani
We describe the development of the practical manufacturing of Ensitrelvir, which was discovered as a SARS-CoV-2 antiviral candidate. Scalable synthetic methods of indazole, 1,2,4-triazole and 1,3,5-triazinone structures were established, and converge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6fe8efc31eb0dbe319232ced6f96b7a
https://doi.org/10.26434/chemrxiv-2022-wx3nl
https://doi.org/10.26434/chemrxiv-2022-wx3nl
Publikováno v:
Chemistry - A European Journal. 23:12795-12804
Selective dehydrogenative synthesis of imines from a variety of alcohols and amines was developed using the ruthenium complex RuCl2(dppea)2 (6a: dppea = 2-diphenylphosphino-ethylamine) in the presence of catalytic amounts of Zn(OCOCF3)2 and KOtBu, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867fa4dfb5354188cbd6955a15ce75fe
https://doi.org/10.1002/chem.201701342
https://doi.org/10.1002/chem.201701342
Publikováno v:
Advanced Synthesis & Catalysis. 358:1929-1933
We describe a most straightforward synthetic method for preparing neurokinin-1 (NK1) receptor antagonist derivatives by asymmetric hydrogenation of 3-amido-2-arylpyridinium salts using dinuclear iridium complexes with enantiopure diphosphine ligands,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b320b760739804cd7154572606f849c9
https://doi.org/10.1002/adsc.201600203
https://doi.org/10.1002/adsc.201600203
Publikováno v:
Angewandte Chemie International Edition. 52:2046-2050
In the presence of a chiral iridium catalyst, 1- and 3-substituted as well as 1,3-disubstituted isoquinolinium salts can be hydrogenated, giving the corresponding 1,2,3,4-tetrahydroisoquinolines in high enantiomeric excess.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05bf5019a1219eb305fd61e9f83160a8
https://doi.org/10.1002/anie.201207748
https://doi.org/10.1002/anie.201207748
Publikováno v:
ChemInform. 47
We describe a most straightforward synthetic method for preparing neurokinin-1 (NK1) receptor antagonist derivatives by asymmetric hydrogenation of 3-amido-2-arylpyridinium salts using dinuclear iridium complexes with enantiopure diphosphine ligands,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8741d90d8a5a3af0430362ccd656b9f0
https://doi.org/10.1002/chin.201643025
https://doi.org/10.1002/chin.201643025
Publikováno v:
Chemical record (New York, N.Y.). 16(6)
Iridium(III) complexes bearing chiral ligands have proved to be active species in asymmetric hydrogenation of C=N bonds, though there are only a few iridium(III) precursors. We prepared triply halide-bridged dinuclear iridium complexes bearing chiral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113cd31af26832db52f61acc0896064f
https://pubmed.ncbi.nlm.nih.gov/27506643
https://pubmed.ncbi.nlm.nih.gov/27506643
Autor:
Antonio Togni, Kazushi Mashima, Rino Schwenk, Yusuke Kita, Takashi Ohshima, Atsuhiro Iimuro, Takuto Nagano
Publikováno v:
Chemistry - A European Journal. 18:11578-11592
The additive effects of amines were realized in the asymmetric hydrogenation of 2-phenylquinoxaline, and its derivatives, catalyzed by chiral cationic dinuclear triply halide-bridged iridium complexes [{Ir(H)[diphosphine]}(2)(μ-X)(3)]X (diphosphine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266b9153f01fa3777f950dfa7a971e06
https://doi.org/10.1002/chem.201201366
https://doi.org/10.1002/chem.201201366
Publikováno v:
Chemistry Letters. 43:284-286
A salt formation strategy for asymmetric hydrogenation of pyridines is described. Poly-substituted pyridinium salts were successfully hydrogenated using chiral iridium dinuclear complexes to afford...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::386d70c2fda4b5e728e0333b66bef76f
https://doi.org/10.1246/cl.130943
https://doi.org/10.1246/cl.130943