Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Atsuhiko Toyama"'
Autor:
Tetsuro Matsunaga, Hirohito Sano, Katsuya Takita, Masanobu Morita, Shun Yamanaka, Tomohiro Ichikawa, Tadahisa Numakura, Tomoaki Ida, Minkyung Jung, Seiryo Ogata, Sunghyeon Yoon, Naoya Fujino, Yorihiko Kyogoku, Yusaku Sasaki, Akira Koarai, Tsutomu Tamada, Atsuhiko Toyama, Takakazu Nakabayashi, Lisa Kageyama, Shigeru Kyuwa, Kenji Inaba, Satoshi Watanabe, Péter Nagy, Tomohiro Sawa, Hiroyuki Oshiumi, Masakazu Ichinose, Mitsuhiro Yamada, Hisatoshi Sugiura, Fan-Yan Wei, Hozumi Motohashi, Takaaki Akaike
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-25 (2023)
Abstract Supersulphides are inorganic and organic sulphides with sulphur catenation with diverse physiological functions. Their synthesis is mainly mediated by mitochondrial cysteinyl-tRNA synthetase (CARS2) that functions as a principal cysteine per
Externí odkaz:
https://doaj.org/article/1a6db92f44634602affb96764e95005a
Autor:
Koji Ueda, Naomi Saichi, Sachiko Takami, Daechun Kang, Atsuhiko Toyama, Yataro Daigo, Nobuhisa Ishikawa, Nobuoki Kohno, Kenji Tamura, Taro Shuin, Masato Nakayama, Taka-Aki Sato, Yusuke Nakamura, Hidewaki Nakagawa
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18567 (2011)
The mass spectrometry-based peptidomics approaches have proven its usefulness in several areas such as the discovery of physiologically active peptides or biomarker candidates derived from various biological fluids including blood and cerebrospinal f
Externí odkaz:
https://doaj.org/article/e0141fc38cd34060a50784feb68d9c30
Publikováno v:
Journal of the Mass Spectrometry Society of Japan. 70:241-244
Publikováno v:
Biochimica et biophysica acta. Proteins and proteomics. 1866(7)
Many post-translational modifications such as oxidation, deamidation and isomerization of amino acid residues occur in lens proteins with aging. One such modification, isomerization of aspartate in lens α-crystallin, has been well studied by amino a
Autor:
Ayako Tatsuguchi, Hidewaki Nakagawa, Masato Nakayama, Koji Ueda, Mutsuo Furihata, Ryo Takata, Osamu Ogawa, Taro Shuin, Yusuke Nakamura, Masahiro Igarashi, Taka-Aki Sato, Tomoaki Fujioka, Atsuhiko Toyama, Kenji Tamura, Shusuke Akamatsu, Naomi Saichi
Publikováno v:
Journal of Proteome Research. 12:4497-4506
In prostate cancer diagnosis, PSA test has greatly contributed to the early detection of prostate cancer; however, expanding overdiagnosis and unnecessary biopsies have emerged as serious issues. To explore plasma biomarkers complementing the specifi
Publikováno v:
Rapid Communications in Mass Spectrometry. 25:3521-3526
One-step detection of biological molecules is one of the principal techniques for clinical diagnosis, and the potential of mass spectrometry for biomarker detection has been a promising new approach in the field of medical sciences. We demonstrate he
Autor:
Satoshi Yamauchi, Hideshi Fujiwake, Atsuhiro Kanzaki, Atsuhiko Toyama, Takashi Shimada, Tsuyoshi Nakanishi, Takaaki Sato, Masaya Ikegawa
Publikováno v:
Journal of Proteome Research. 9:4490-4500
Bile acids have recently emerged as versatile signaling molecules, and their signaling pathway is a promising target for the treatment of metabolic diseases. Here, we developed a highly sensitive and high-throughput quantification method for six taur
Autor:
Takaaki Sato, Yataro Daigo, Daisuke Aoki, Takashi Shimada, Chikage Aoki, Yukari Umino, Yusuke Nakamura, Yutaka Aoki, Atsushi Suzuki, Tetsuyoshi Sugita, Atsuhiko Toyama
Publikováno v:
Proceedings of the Japan Academy, Series B. 83:205-214
Significant advances have been made in the past decade in the field of mass spectrometry imaging (MS imaging). It is a relatively unestablished technique aimed at direct, high-sensitive and spatially exclusive detection of biological molecules from t
Autor:
Koji Ueda, Hidewaki Nakagawa, Yusuke Nakamura, Taka-Aki Sato, Koichi Matsuda, Atsuhiko Toyama
Publikováno v:
Analytical chemistry. 84(22)
Site-specific characterization of glycoform heterogeneity currently requires glycan structure assignment and glycopeptide quantification in two independent experiments. We present here a new method combining multiple reaction monitoring mass spectrom
Autor:
Takashi, Shimada, Atsuhiko, Toyama, Chikage, Aoki, Yutaka, Aoki, Koichi, Tanaka, Taka-Aki, Sato
Publikováno v:
Rapid communications in mass spectrometry : RCM. 25(23)
One-step detection of biological molecules is one of the principal techniques for clinical diagnosis, and the potential of mass spectrometry for biomarker detection has been a promising new approach in the field of medical sciences. We demonstrate he