Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Atso Raasmaja"'
Autor:
Nadia Schendzielorz, Juha-Pekka Oinas, Timo T Myöhänen, Ilkka Reenilä, Atso Raasmaja, Pekka T Männistö
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61392 (2013)
The occurrence of catechol-O-methyltransferase (COMT) in presynaptic neurons remains controversial. This study utilized dopaminergic and noradrenergic toxins to assess the presence of COMT in the presynaptic neurons originating from the substantia ni
Externí odkaz:
https://doaj.org/article/d46a53daed10414a835828b620908505
Autor:
Petteri Piepponen, Ville Oinio, Mikko Sundstrom, Johanna Uhari-Väänänen, Kalervo Kiianmaa, Pia Bäckström, Atso Raasmaja
Research has highlighted the association of a positive family history of alcoholism with a positive treatment response to opioid antagonists in those with a gambling disorder. However, the role of the opioidergic system in gambling behavior is not we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458f14be3385aec6d2ad528e5e35c589
http://hdl.handle.net/10138/342261
http://hdl.handle.net/10138/342261
Publikováno v:
Molecular genetics and metabolism. 134(1-2)
Wolfram syndrome is a rare autosomal recessive disorder caused by mutations in the wolframin ER transmembrane glycoprotein (WFS1) gene and characterized by diabetes mellitus, diabetes insipidus, optic atrophy and deafness. In experimental models the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beea7278c5b570d8ff9ba3ba1b4c4491
https://pubmed.ncbi.nlm.nih.gov/34312071
https://pubmed.ncbi.nlm.nih.gov/34312071
Autor:
Johanna Uhari-Väänänen, Petteri Piepponen, Kalervo Kiianmaa, Mikko Sundstrom, Ville Oinio, Atso Raasmaja, Pia Bäckström
Publikováno v:
Psychopharmacology. 235:1361-1370
Comorbidity with gambling disorder (GD) and alcohol use disorder (AUD) is well documented. The purpose of our study was to examine the influence of genetic alcohol drinking tendency on reward-guided decision making behavior of rats and the impact of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5fa0a33f0275cb4bf80774b57cbf76
https://doi.org/10.1007/s00213-018-4847-2
https://doi.org/10.1007/s00213-018-4847-2
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 9
International Journal of Molecular Sciences, Vol 20, Iss 9, p 2054 (2019)
Volume 20
Issue 9
International Journal of Molecular Sciences, Vol 20, Iss 9, p 2054 (2019)
Juniper (Juniperus communis L.) is a northern coniferous plant generally used as a spice and for nutritional purposes in foods and drinks. It was previously reported that juniper extract (JE) affects p53 activity, cellular stress, and gene expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14138c15a9d718f54185137fca49eb6
Publikováno v:
International Journal of Molecular Sciences
Juniper (Juniperus communis L.) is a northern coniferous plant generally used as a spice and for nutritional purposes in foods and drinks. It was previously reported that juniper extract (JE) affects p53 activity, cellular stress, and gene expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bce6b3bb1c5ea6d4c7ad95d8392a8072
https://pubmed.ncbi.nlm.nih.gov/31027321
https://pubmed.ncbi.nlm.nih.gov/31027321
Autor:
F. Ivy Carroll, Kalervo Kiianmaa, Tony Eteläinen, Petteri Piepponen, Pia Bäckström, Atso Raasmaja, Ville Oinio, Johanna Uhari-Väänänen
Publikováno v:
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 29(12)
The mechanisms behind relapse to ethanol intake in recovering alcoholics are still unclear. The negative reinforcing effects contributing to ethanol addiction, including relapse, are considered to be partly driven by the kappa-opioidergic system. As
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61fc25b8bd6c83926524383bbedbbd96
https://pubmed.ncbi.nlm.nih.gov/31679889
https://pubmed.ncbi.nlm.nih.gov/31679889
Autor:
Ville Oinio, Mikko Airavaara, Petteri Piepponen, Atso Raasmaja, Pia Bäckström, Johanna Uhari-Väänänen, Kalervo Kiianmaa
Publikováno v:
Alcoholism: Clinical and Experimental Research. 40:2114-2123
Background The nucleus accumbens shell is a key brain area mediating the reinforcing effects of ethanol (EtOH). Previously, it has been shown that the density of μ-opioid receptors in the nucleus accumbens shell is higher in alcohol-preferring Alko
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e462f4c9497f6a19511563f2bc10a71
https://doi.org/10.1111/acer.13176
https://doi.org/10.1111/acer.13176
Autor:
F. Ivy Carroll, Petteri Piepponen, Atso Raasmaja, Ville Oinio, Johanna Uhari-Väänänen, Kalervo Kiianmaa, Mikko Airavaara, Pia Bäckström
Studies suggest that the kappa-opioidergic system becomes overactivated as ethanol use disorders develop. Nalmefene, a currently approved treatment for ethanol use disorders, may also elicit some of its main effects via the kappa-opioidergic system.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a05f63cda9a147591d8c374e701b484
http://hdl.handle.net/10138/308977
http://hdl.handle.net/10138/308977
Autor:
Pasi Lampela, Anne Lecklin, Tiina M. Kääriäinen, Šárka Lehtonen, Atso Raasmaja, Marko Huotari
Publikováno v:
Open Journal of Genetics. :30-37
The use of gene therapy has been intensively studied as a potential method to treat Parkinson’s disease (PD) and other degenerative brain diseases. However, the effects of experimental measures and approaches on the outcome of gene delivery or on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dad19f1d1f638ef0860fff04602ccbf2
https://doi.org/10.4236/ojgen.2013.32a1004
https://doi.org/10.4236/ojgen.2013.32a1004