Výsledky vyhledávání - "Atrial effective refractory period"

Akademický článek

Simultaneous analyses of hemodynamic and electrophysiological effects of oseltamivir along with its pharmacokinetic profile using the canine paroxysmal atrial fibrillation model

Autor: Ryuichi Kambayashi, Ai Goto, Mayu Onozato, Hiroko Izumi-Nakaseko, Yoshinori Takei, Akio Matsumoto, Shinichi Kawai, Takeshi Fukushima, Atsushi Sugiyama

Publikováno v: Journal of Pharmacological Sciences, Vol 148, Iss 1, Pp 179-186 (2022)

Since information of antiviral drug oseltamivir on the anti-atrial fibrillation (AF) property is still limited, we assessed it using the canine paroxysmal AF model. Oseltamivir in doses of 3 and 30 mg/kg/10 min was intravenously infused to the isoflu

Externí odkaz: https://doaj.org/article/2f33f0d0210d45fd9ff92aaa89defa9c

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A new implantable tool for repeated assessment of supraventricular electrophysiology and atrial fibrillation susceptibility in freely moving rats

Autor: Or Levi, Roni Gillis, Hadar Klapper-Goldstein, Michael Murninkas, Danielle I. Lee, Rotem Polak, Yoram Etzion, Sigal Elyagon, Wesam Mulla, Nikhil S. Bhandarkar

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 320:H713-H724

The complex pathophysiology of atrial fibrillation (AF) is governed by multiple risk factors in ways that are still elusive. Basic electrophysiological properties, including atrial effective refractory period (AERP) and conduction velocity, are major

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c0e1aca427c729f6d5e949863775c0b
https://doi.org/10.1152/ajpheart.00676.2020

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An exploratory analysis of effects of poyendarone, a deuterated analogue of dronedarone, on the canine model of paroxysmal atrial fibrillation

Autor: Akio Matsumoto, Eric Chun Yong Chan, Yoshio Nunoi, Mihoko Hagiwara-Nagasawa, Hiroko Izumi-Nakaseko, Ryuichi Kambayashi, Gopalakrishnan Venkatesan, Yoshinori Takei, Ai Goto, Atsushi Sugiyama

Publikováno v: Naunyn-Schmiedeberg's Archives of Pharmacology. 394:1103-1112

Poyendarone, a deuterated analogue of dronedarone, is expected to reduce the onset of cardiovascular adverse events of dronedarone, including congestive heart failure and excessive QT-interval prolongation. Since information is still lacking on the a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62628ec7b3adfc0dadd97bb1ad526ad2
https://doi.org/10.1007/s00210-020-02047-1

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Investigational Anti–Atrial Fibrillation Pharmacology and Mechanisms by Which Antiarrhythmics Terminate the Arrhythmia: Where Are We in 2020?

Autor: Alexander Burashnikov

Publikováno v: Journal of Cardiovascular Pharmacology

Antiarrhythmic drugs remain the mainstay therapy for patients with atrial fibrillation (AF). A major disadvantage of the currently available anti-AF agents is the risk of induction of ventricular proarrhythmias. Aiming to reduce this risk, several at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d89e2be2b5324f9f0fc7aa4b0963d5
http://europepmc.org/articles/PMC7641178

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Simultaneous analyses of hemodynamic and electrophysiological effects of oseltamivir along with its pharmacokinetic profile using the canine paroxysmal atrial fibrillation model

Autor: Akio Matsumoto, Takeshi Fukushima, Atsushi Sugiyama, Ryuichi Kambayashi, Shinichi Kawai, Mayu Onozato, Ai Goto, Hiroko Izumi-Nakaseko, Yoshinori Takei

Publikováno v: Journal of Pharmacological Sciences, Vol 148, Iss 1, Pp 179-186 (2022)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed8361282e4a11b1d1b6b091df3d959
https://pubmed.ncbi.nlm.nih.gov/34924124

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Neuromodulation for the Treatment of Heart Rhythm Disorders

Autor: Marat Fudim, Joseph P. Mathew, Nathan H. Waldron, Jonathan P. Piccini

Publikováno v: JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 4, Iss 4, Pp 546-562 (2019)

Highlights • Derangement of autonomic nervous signaling is an important contributor to cardiac arrhythmogenesis. • Modulation of autonomic nervous signaling holds significant promise for the prevention and treatment of cardiac arrhythmias. • Fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b674375a735dcc07e7dcffe2ceffab27
http://europepmc.org/articles/PMC6712352

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Exploring Refractoriness as an Adjunctive Electrical Biomarker for Staging of Atrial Fibrillation

Autor: Lianne N. van Staveren, Natasja M.S. de Groot

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Journal of the American Heart Association, 9(23). Wiley

Patients diagnosed with the same subtype of atrial fibrillation according to our current classification system may differ in symptom severity, severity of the arrhythmogenic substrate, and response to antiarrhythmic therapy. Hence, there is a need fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50eb16190b2a2a385018c05cec8d8c5a
https://pubmed.ncbi.nlm.nih.gov/33238778

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Akademický článek

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