Zobrazeno 1 - 10
of 474
pro vyhledávání: '"Atopic dermatitis (AD)"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 10, Pp 10714-10730 (2024)
Chronic allergic skin conditions, including atopic dermatitis (AD), are characterized by pruritus, erythema, xerosis, desquamation, and inflammation, significantly impacting quality of life. Long-term steroid use, while common in treatment, carries t
Externí odkaz:
https://doaj.org/article/6021ee12262b469c8536ecd21895db21
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ImportanceDue to comorbidities and associated safety risks, the management of severe atopic dermatitis (AD) in pediatric and adolescent patients poses significant challenges.ObjectiveTo examine the efficacy and safety of systemic therapies for the tr
Externí odkaz:
https://doaj.org/article/70275d8192964159b802c158bccb7d35
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 43, Iss 8, Pp 1049-1055 (2023)
Atopic dermatitis (AD) is a chronic inflammatory skin disease with the highest incidence in the world. The main clinical manifestations are eczema-like skin lesions, pruritus and xeroderma. Recent studies have revealed that sensory neurons in the ski
Externí odkaz:
https://doaj.org/article/72235d74f6314c2aa90bf989ddd16c44
Autor:
Peter Seiringer, Christina Hillig, Alexander Schäbitz, Manja Jargosch, Anna Caroline Pilz, Stefanie Eyerich, Andrea Szegedi, Michaela Sochorová, Florian Gruber, Christos C. Zouboulis, Tilo Biedermann, Michael P. Menden, Kilian Eyerich, Daniel Törőcsik
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Sebaceous glands drive acne, however, their role in other inflammatory skin diseases remains unclear. To shed light on their potential contribution to disease development, we investigated the spatial transcriptome of sebaceous glands in psoriasis and
Externí odkaz:
https://doaj.org/article/344dfef1bc99426eb7080f48d5482406
Autor:
Krzysztof Sitko, Sarolta Kárpáti, Grzegorz Węgrzyn, Grzegorz Mincewicz, Magdalena Trzeciak, Michael Kasperkiewicz, Stefan Tukaj
Publikováno v:
Frontiers in Medicine, Vol 10 (2024)
Heat shock protein 90 alpha (Hsp90α) is one of the key intra- and extracellular chaperones responsible for the biological activity of various signaling molecules that are involved in (auto)immune-mediated inflammatory diseases. Recent epidemiologic
Externí odkaz:
https://doaj.org/article/9fc912abf4204c8ab6f0d0a8963215aa
Autor:
Lina Renkhold, Henning Wiegmann, Bettina Pfleiderer, Aysenur Süer, Claudia Zeidler, Manuel P. Pereira, Martin Schmelz, Sonja Ständer, Konstantin Agelopoulos
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
BackgroundChronic scratching imposes a major stress on the skin and can lead to itch intensity worsening, and consequently, patients may enter an itch–scratch cycle. This repetitive mechanical stress can result in lichenification, worsening of epid
Externí odkaz:
https://doaj.org/article/4a8f456812bc43c19ae399213cef7cd6
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Frequent use of hormones and drugs may be associated with side-effects. Recent studies have shown that probiotics have effects on the prevention and treatment of immune-related diseases. Limosilactobacillus reuteri (L. reuteri) had regulatory effects
Externí odkaz:
https://doaj.org/article/38ad47dd596c4dfcb73be1c2c00ffdc1
Autor:
Maddalena Napolitano, Francesca di Vico, Angelo Ruggiero, Gabriella Fabbrocini, Cataldo Patruno
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Recent evidence suggests that interleukin (IL)-13 is a crucial cytokine involved in the pathogenesis of atopic dermatitis (AD). It is a central driver of type-2 T-helper inflammation and is overexpressed in lesional skin of AD patients. Upon release
Externí odkaz:
https://doaj.org/article/e8063f5fe672436d90c7c05472682312
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Despite its harsh and dry environment, human skin is home to diverse microbes, including bacteria, fungi, viruses, and microscopic mites. These microbes form communities that may exist at the skin surface, deeper skin layers, and within microhabitats
Externí odkaz:
https://doaj.org/article/b7836870fc82474b9d00fdea5d84d085
Autor:
Chandra K. Singh, Charlotte A. Mintie, Mary A. Ndiaye, Gagan Chhabra, Sushmita Roy, Ruth Sullivan, B. Jack Longley, Stefan M. Schieke, Nihal Ahmad
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Atopic dermatitis (AD) is a chronic inflammatory skin disease with significant health/economic burdens. Existing therapies are not fully effective, necessitating development of new approaches for AD management. Here, we report that dietary grape powd
Externí odkaz:
https://doaj.org/article/4b01c6cb607c4b6ca5a31d4b1b70abb1