Výsledky vyhledávání - "Atopic Dermatitis, Urticaria and Skin Disease"

Impact of anxiety, stress and depression related to COVID‐19 pandemic on the course of hereditary angioedema with C1‐inhibitor deficiency

Autor: Deniz Eyice Karabacak, Osman Ozan Yeğit, Semra Demir, Kadriye Terzioğlu, Raif Coskun, Aslı Gelincik, Muge Olgac, Suna Büyüköztürk, Bahauddin Colakoglu, Ali Can, Derya Erdoğdu

Publikováno v: Allergy

Background: Hereditary angioedema (HAE) attacks can be provoked with psychological factors. The aim of this study was to assess the effects of anxiety, depression and stress related to COVID-19 pandemic on disease activity of HAE patients during the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228c5bc2b37429cc20f75889604e56c5
https://doi.org/10.1111/all.14796

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Impact of lanadelumab on health‐related quality of life in patients with hereditary angioedema in the HELP study

Autor: Marcus Maurer, Hannah B Lewis, Aleena Banerji, Peng Lu, Markus Magerl, Giovanna Devercelli, Gagan Jain, William R. Lumry, Karsten Weller, Marc A. Riedl, Help Study Investigators, Hilary Longhurst

Publikováno v: Allergy

Background An objective of the phase 3 HELP Study was to investigate the effect of lanadelumab on health‐related quality of life (HRQoL) in patients with hereditary angioedema (HAE). Methods Patients with HAE‐1/2 received either lanadelumab 150 m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41cdaebf7486f6e60aedd279ec76dbc
http://europepmc.org/articles/PMC8247292

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Fatty acid‐binding protein 3 controls contact hypersensitivity through regulating skin dermal Vγ4 + γ/δ T cell in a murine model

Autor: Shuhei Kobayashi, Hai The Phung, Yoshiteru Kagawa, Hirofumi Miyazaki, Yu Takahashi, Atsuko Asao, Takashi Maruyama, Akihiko Yoshimura, Naoto Ishii, Yuji Owada

Publikováno v: Allergy

Background Fatty acid‐binding protein 3 (FABP3) is a cytosolic carrier protein of polyunsaturated fatty acids (PUFAs) and regulates cellular metabolism. However, the physiological functions of FABP3 in immune cells and how FABP3 regulates inflammat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb3284a077e6341525160721bba8410
https://doi.org/10.1111/all.14630

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Lanadelumab demonstrates rapid and sustained prevention of hereditary angioedema attacks

Autor: Jonathan A. Bernstein, Aleena Banerji, Marcus Maurer, Peng Lu, Salome Juethner, H. Henry Li, Hilary Longhurst, James Hao, Marc A. Riedl, William R. Lumry, Help Study Investigators

Publikováno v: Allergy
Allergy, vol 75, iss 11

Background Lanadelumab demonstrated efficacy in preventing hereditary angioedema (HAE) attacks in the phase 3 HELP Study. Objective To assess time to onset of effect and long‐term efficacy of lanadelumab, based on exploratory findings from the HELP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa6235c902377cd5373f0ecd7b907e6a
https://doi.org/10.1111/all.14416

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Comel-Netherton syndrome: A local skin barrier defect in the absence of an underlying systemic immunodeficiency

Autor: Suzanne G.M.A. Pasmans, Els van Hoffen, Ruud W. J. Meijers, Susan A M Gerritsen, Menno C. van Zelm, Jorn J. Heeringa, Kira Stuvel, Virgil A. S. H. Dalm

Publikováno v: Allergy: European Journal of Allergy and Clinical Immunology, 75(7), 1710-1720. Wiley-Blackwell Publishing Ltd
Allergy

Background Comel‐Netherton syndrome (NS) is a rare autosomal disease, characterized by severe skin disease, hair shaft defects, atopic diathesis, and increased susceptibility for skin infections. Since patients with NS suffer from recurrent infecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97cf54a6448de91b3fba4cf31420d6f8
https://doi.org/10.1111/all.14197

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Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL‐1β

Autor: Luke A. J. O'Neill, Christian Schwartz, Achilleas Floudas, Patrick T. Walsh, McKenzie Anj., A Kaszlikowska, Yoichiro Iwakura, Alan D. Irvine, Tara Moran, Graham S. Ogg, Padraic G. Fallon, J Bom, Sean P. Saunders, Gabriel Núñez, Jocelyne Demengeot

Publikováno v: Allergy

Background Atopic dermatitis (AD) is one of the most common skin diseases with a multifactorial etiology. Mutations leading to loss of skin barrier function are associated with the development of AD with group 2 innate lymphoid cells (ILC2) promoting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a91668da05304f4119177f50c7da295
https://doi.org/10.1111/all.13801

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Integrative transcriptome analysis deciphers mechanisms of nickel contact dermatitis

Autor: Harri Alenius, Erja Jalonen, Paulina Werner, Angelika Berger, Nanna Fyhrquist, Lukas Wisgrill, Antti Lauerma

Publikováno v: Allergy

Background Nickel‐induced allergic contact dermatitis (nACD) remains a major occupational skin disorder, significantly impacting the quality of life of suffering patients. Complex cellular compositional changes and associated immunological pathways

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbfca96b9d7baaa045146d66205f851d
http://hdl.handle.net/10138/353216

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Microbial and transcriptional differences elucidate atopic dermatitis heterogeneity across skin sites

Autor: Annamari Ranki, Péter Oláh, Lukas Wisgrill, Antti Lauerma, Jonathan Barker, Björn Andersson, Helen Alexander, Francesca Levi-Schaffer, Mauricio Barrientos-Somarribas, Harri Alenius, Vassili Soumelis, Frank O. Nestle, Noora Ottman, Sophia Tsoka, Jens M. Schröder, Juha Kere, Nanna Fyhrquist, Dario Greco, Bernhard Homey

Publikováno v: Allergy

It is well established that different sites in healthy human skin are colonized by distinct microbial communities due to different physiological conditions. However, few studies have explored microbial heterogeneity between skin sites in diseased ski

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8a09af17217e8b99ba6e20b9f53cc6
https://trepo.tuni.fi/handle/10024/127989

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Component-resolved microarray analysis of IgE sensitization profiles to Culicoides recombinant allergens in horses with insect bite hypersensitivity

Autor: Sigridur Jonsdottir, Gertraud Schüpbach-Regula, A D Wilson, Samuel J. White, Sigurbjörg Torsteinsdóttir, Eliane Isabelle Marti, Dania Birte Reiche, Ella N. Novotny, Edwin Tijhaar, Claudio Rhyner, Rebekka Frey, Horst Rose, Sara Bjork Stefansdottir, Marcos J. C. Alcocer

Publikováno v: Allergy
Allergy: European Journal of Allergy and Clinical Immunology 76 (2021) 4
Novotny, Ella N.; White, Samuel J.; Wilson, A. Douglas; Stefánsdóttir, Sara B.; Tijhaar, Edwin; Jonsdóttir, Sigridur; Frey, Rebekka; Reiche, Dania; Rose, Horst; Rhyner, Claudio; Schüpbach, Gertraud; Torsteinsdóttir, Sigurbjörg; Alcocer, Marcos; Marti, Eliane (2021). Component-resolved microarray analysis of IgE sensitization profiles to Culicoides recombinant allergens in horses with insect bite hypersensitivity. Allergy, 76(4), pp. 1147-1157. Wiley-Blackwell 10.1111/all.14556
Allergy: European Journal of Allergy and Clinical Immunology, 76(4), 1147-1157

Background Allergy to bites of blood‐sucking insects, including biting midges, can affect both human and veterinary patients. Horses are often suffering from an IgE‐mediated allergic dermatitis caused by bites of midges (Culicoides spp). With the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca25a5e5340347a9ba2ad261bec02ca0
https://pubmed.ncbi.nlm.nih.gov/32780483

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