Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Atish Mohanty"'
Autor:
Erminia Massarelli, Ravi Salgia, Diana Bell, Haiqing Li, Arya Amini, Sue Chang, Atish Mohanty, Michelle Afkhami, Amanda Reyes, Rebecca Pharaon, Holly Yin, Dana Do, Arin Nam, Thomas Gernon, Robert Kang, Sagus Sampath, Prakash Kulkarni, Raju Pillai, Vicky Villaflor, Ellie Maghami
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background The study summarizes the potential use of immunotherapy for BRAF-mutated papillary thyroid cancer (PTC) by analyzing the immune profile of City of Hope PTC patient samples and comparing them to the thyroid dataset available in the TCGA dat
Externí odkaz:
https://doaj.org/article/f8577052c6e344559c40dcdf83560db4
Autor:
Ayalur Raghu Subbalakshmi, Sravani Ramisetty, Atish Mohanty, Siddhika Pareek, Dana Do, Sagun Shrestha, Ajaz Khan, Neel Talwar, Tingting Tan, Priya Vishnubhotla, Sharad S. Singhal, Ravi Salgia, Prakash Kulkarni
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 15, p 4302 (2024)
Epithelial-to-mesenchymal transition (EMT) is a major axis of phenotypic plasticity not only in diseased conditions such as cancer metastasis and fibrosis but also during normal development and wound healing. Yet-another important axis of plasticity
Externí odkaz:
https://doaj.org/article/9ec2fe30968046059258eb6b3591c9f9
Autor:
Sravani Ramisetty, Ayalur Raghu Subbalakshmi, Siddhika Pareek, Tamara Mirzapoiazova, Dana Do, Dhivya Prabhakar, Evan Pisick, Sagun Shrestha, Srisairam Achuthan, Supriyo Bhattacharya, Jyoti Malhotra, Atish Mohanty, Sharad S. Singhal, Ravi Salgia, Prakash Kulkarni
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 11, p 3337 (2024)
Cancer cells, like all other organisms, are adept at switching their phenotype to adjust to the changes in their environment. Thus, phenotypic plasticity is a quantitative trait that confers a fitness advantage to the cancer cell by altering its phen
Externí odkaz:
https://doaj.org/article/10574b8ac1364d809793629f45a31a3e
Autor:
Linlin Guo, Atish Mohanty, Sharad Singhal, Saumya Srivastava, Arin Nam, Charles Warden, Sravani Ramisetty, Yate-Ching Yuan, Hyejin Cho, Xiwei Wu, Aimin Li, Manik Vohra, Srinivas Vinod Saladi, Deric Wheeler, Leonidas Arvanitis, Erminia Massarelli, Prakash Kulkarni, Yiming Zeng, Ravi Salgia
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107302- (2023)
Summary: This study investigates the role of integrin β4 (ITGB4) and stemness-associated factor SOX2 in platinum resistance in lung squamous cell carcinoma (LUSC). The expression of SOX2 and ITGB4 is found to be high in all LUSC subtypes, but the im
Externí odkaz:
https://doaj.org/article/9962e7214592483093812b263a3e559e
Autor:
Prakash Kulkarni, Atish Mohanty, Sravani Ramisetty, Herbert Duvivier, Ajaz Khan, Sagun Shrestha, Tingting Tan, Amartej Merla, Michelle El-Hajjaoui, Jyoti Malhotra, Sharad Singhal, Ravi Salgia
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1587 (2023)
Several studies in the last few years have determined that, in contrast to the prevailing dogma that drug resistance is simply due to Darwinian evolution—the selection of mutant clones in response to drug treatment—non-genetic changes can also le
Externí odkaz:
https://doaj.org/article/2fb06324c434450dabc396224a13cca1
Publikováno v:
Cancers, Vol 15, Iss 12, p 3162 (2023)
Lung cancer is one of the most common cancers with the highest mortality. Non-small cell lung cancer (NSCLC) contributes to around 85% of lung cancer diagnoses (vs. 15% for small cell lung cancer). The treatment of NSCLC has vastly changed in the las
Externí odkaz:
https://doaj.org/article/d2635e1f4fa848358f9c1a9eedbfb1fd
Autor:
Sharad S. Singhal, Rachana Garg, Atish Mohanty, Pankaj Garg, Sravani Keerthi Ramisetty, Tamara Mirzapoiazova, Raffaella Soldi, Sunil Sharma, Prakash Kulkarni, Ravi Salgia
Publikováno v:
Cancers, Vol 15, Iss 11, p 2961 (2023)
Animal models have been utilized for decades to investigate the causes of human diseases and provide platforms for testing novel therapies. Indeed, breakthrough advances in genetically engineered mouse (GEM) models and xenograft transplantation techn
Externí odkaz:
https://doaj.org/article/d0a93eb9703e43b998122cda63541560
Autor:
Sravani Ramisetty, Prakash Kulkarni, Supriyo Bhattacharya, Arin Nam, Sharad S. Singhal, Linlin Guo, Tamara Mirzapoiazova, Bolot Mambetsariev, Sandeep Mittan, Jyoti Malhotra, Evan Pisick, Shanmuga Subbiah, Swapnil Rajurkar, Erminia Massarelli, Ravi Salgia, Atish Mohanty
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 2, p 599 (2023)
Translational research in medicine, defined as the transfer of knowledge and discovery from the basic sciences to the clinic, is typically achieved through interactions between members across scientific disciplines to overcome the traditional silos w
Externí odkaz:
https://doaj.org/article/1fd5f4286c2c46098c48b73564376a90
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 99 (2022)
Autoimmunity and cancer rates have both been on the rise in Western civilization prompting many to investigate the link between the two entities. This review will investigate the complex interactions between the activation and deactivation of the imm
Externí odkaz:
https://doaj.org/article/606251773bca4b29855093980539ebe4
Autor:
Prakash Kulkarni, Atish Mohanty, Supriyo Bhattacharya, Sharad Singhal, Linlin Guo, Sravani Ramisetty, Tamara Mirzapoiazova, Bolot Mambetsariev, Sandeep Mittan, Jyoti Malhotra, Naveen Gupta, Pauline Kim, Razmig Babikian, Swapnil Rajurkar, Shanmuga Subbiah, Tingting Tan, Danny Nguyen, Amartej Merla, Sudarsan V. Kollimuttathuillam, Tanyanika Phillips, Peter Baik, Bradford Tan, Pankaj Vashi, Sagun Shrestha, Benjamin Leach, Ruchi Garg, Patricia L. Rich, F. Marc Stewart, Evan Pisick, Ravi Salgia
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 19, p 5701 (2022)
Drug resistance remains one of the major impediments to treating cancer. Although many patients respond well initially, resistance to therapy typically ensues. Several confounding factors appear to contribute to this challenge. Here, we first discuss
Externí odkaz:
https://doaj.org/article/c68c5aa9355c44d1bc38a6211695ea17