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pro vyhledávání: '"Atira Hardiman Dudley"'
Autor:
Nancy Ratner, Grier P. Page, David Eaves, Tilat A. Rizvi, Mi-Ok Kim, Jianqiang Wu, Jessica Sabo, Meghan E. Brundage, Marco Giovannini, Edwin Jousma, Shyra J. Miller, Michiko Niwa-Kawakita, Brigitte C. Widemann, Timothy P. Cripe, Walter J. Jessen, Eva Dombi, Bruce J. Aronow, Atira Hardiman Dudley
Publikováno v:
Journal of Clinical Investigation. 123:340-347
Neurofibromatosis type 1 (NF1) patients develop benign neurofibromas and malignant peripheral nerve sheath tumors (MPNST). These incurable peripheral nerve tumors result from loss of NF1 tumor suppressor gene function, causing hyperactive Ras signali