Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Atimé Djimdé"'
Autor:
Jean-Edouard Ombetta, Natacha Thelier, Chang Zhi Dong, Stéphanie Plocki, Lydia Tsagris, François Rannou, France Massicot, Atimé Djimdé, Elissar El-Hayek, Yiming Shi, Françoise Heymans, Nohad Gresh, Caroline Chauvet
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e10914 (2010)
Group IIA secreted/synovial phospholipase A(2) (GIIAPLA(2)) is an enzyme involved in the synthesis of eicosanoids such as prostaglandin E(2) (PGE(2)), the main eicosanoid contributing to pain and inflammation in rheumatic diseases. We designed, by mo
Externí odkaz:
https://doaj.org/article/08b29ccca8db43b08730c735e6c9c05e
Autor:
Chang-Ha Park, Aazdine Lamouri, Atimé Djimdé, Joo-Hyoung Yoon, Nadia Meddad-Belhabich, Latifa Boukli, Mohamed Touaibia, Jung-Joo Kim, Françoise Heymans
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:1242-1253
Among the different PLA2s identified to date, the group IIA secretory PLA2 (sPLA2 GIIA) is implied in diverse pathological conditions. In this work we describe the synthesis, inhibitory activities, and structure–activity relationships (SAR) of a ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7e0bc0fe66e6713e9771738af8008b
https://doi.org/10.1016/j.bmc.2007.10.077
https://doi.org/10.1016/j.bmc.2007.10.077
Autor:
Nadia Meddad-Belhabich, Darina Aoun, Atimé Djimdé, Catherine Redeuilh, Georges Dive, France Massicot, François Chau, Françoise Heymans, Aazdine Lamouri
Publikováno v:
Bioorganicmedicinal chemistry. 18(10)
The group IIA human non-pancreatic secretory phospholipase A 2 (hnp-sPLA 2 ) is one of the enzymes implied in the inflammatory process. In the course of our work on inhibitors of this enzyme we investigated the influence of rigidity of the piperazine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027ab26db138f06c462342cc14bfea0d
https://pubmed.ncbi.nlm.nih.gov/20417107
https://pubmed.ncbi.nlm.nih.gov/20417107
Autor:
Mohamed Touaibia, Atimé Djimdé, Fei Cao, Eric Boilard, Sofiane Bezzine, Gérard Lambeau, Catherine Redeuilh, Aazdine Lamouri, France Massicot, François Chau, Chang-Zhi Dong, Françoise Heymans
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2007, 50 (7), pp.1618-26. ⟨10.1021/jm060082n⟩
Journal of Medicinal Chemistry, American Chemical Society, 2007, 50 (7), pp.1618-26. ⟨10.1021/jm060082n⟩
Secreted phospholipases A2 (sPLA2s) have been reported to play an important role in various inflammatory conditions and thus represent an attractive therapeutic target. Previous SAR studies from our laboratory have revealed certain important features
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f45d463521ddcbdf1b76b9d6429099d
https://pubmed.ncbi.nlm.nih.gov/17335183
https://pubmed.ncbi.nlm.nih.gov/17335183