Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Atilla Bozkurt"'
Publikováno v:
Cukurova Medical Journal, Vol 47, Iss 3, Pp 1015-1023 (2022)
Purpose: In this study, the possible effects of CYP2C9 polymorphisms on the clinical response to losartan were investigated in a group of hypertensive patients. Materials and Methods: Seventy-four patients, newly diagnosed to have essential hypertens
Externí odkaz:
https://doaj.org/article/80ad30cf17b34a588b83796ca80f079c
Autor:
Ragip Ozgur Karaca, Lokman Cevik, Mustafa Tugrul Goktas, Said Kalkisim, Levent Kilic, Ali Akdogan, Atilla Bozkurt, Umit Yasar, Melih O. Babaoglu, Leif Bertilsson
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 121:266-271
Behçet's disease (BD) is a systemic autoimmune disorder. Cytochrome P450 enzymes (CYPs) are responsible for various drug metabolism reactions as well as those of endogenous substances which may be associated with autoimmune disease susceptibility. R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f06c142c68918c3ae48fb8f2f4af54e
https://doi.org/10.1111/bcpt.12710
https://doi.org/10.1111/bcpt.12710
Autor:
Umit Yasar, Said Kalkisim, Serta Kilincalp, Atilla Bozkurt, R. Özgür Karaca, İlhami Yüksel, Melih O. Babaoglu, Akif Altinbas, Mustafa Tugrul Goktas
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 120:199-206
Pantoprazole is a proton pump inhibitor that is commonly used in the treatment of peptic ulcer disease (PUD) and metabolized by cytochrome P450 (CYP) enzymes CYP2C19 and CYP3A4. Pantoprazole is a substrate for multi-drug resistance protein 1 (MDR1).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7778b6f93da64a8be1e7be176a7c0db1
https://doi.org/10.1111/bcpt.12667
https://doi.org/10.1111/bcpt.12667
Autor:
R. Özgür Karaca, Melih O. Babaoglu, Ahmet Muderrisoglu, Nurhayat Eni, Gökhan Yoca, Yavuz Ayhan, A. Elif Anil Yağcioğlu, Mustafa Tugrul Goktas, Atilla Bozkurt, Lokman Cevik, M. Kâzım Yazıcı
Publikováno v:
Journal of Clinical Psychopharmacology. 36:257-261
Clozapine use is associated with leukopenia and more rarely agranulocytosis, which may be lethal. The drug and its metabolites are proposed to interact with the multidrug resistance transporter (ABCB1/MDR1) gene product, P-glycoprotein (P-gp). Among
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d842b714106213df3f736674bb74a9
https://doi.org/10.1097/jcp.0000000000000495
https://doi.org/10.1097/jcp.0000000000000495
Autor:
Melih O. Babaoglu, Fazleen Haslinda Mohd Hatta, Ozgur Karaca, Anders Helldén, Ali Akdogan, Leif Bertilsson, Said Kalkisim, Mustafa Tugrul Goktas, Atilla Bozkurt, Levent Kilic, Umit Yasar
Publikováno v:
European Journal of Clinical Pharmacology. 71:1223-1228
We previously reported on a Swedish patient with Behcet’s disease (BD) who was an ultra-rapid metaboliser of drugs catalysed by CYP2C9. Was this extreme metabolism caused by the disease? This study aims to compare the genotype/phenotype of CYP2C9 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae08a13a959c3504b6b627f10962b75
https://doi.org/10.1007/s00228-015-1899-7
https://doi.org/10.1007/s00228-015-1899-7
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 116:354-360
Chemotherapy-induced nausea and vomiting (CINV) remains a major adverse effect decreasing quality of life in patients with cancer. Genetic variations among patients may be responsible for part of the lack of efficacy of anti-emetic drugs. The aim of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd8914d9c7a2af64815e0efdd75b2ea7
https://doi.org/10.1111/bcpt.12334
https://doi.org/10.1111/bcpt.12334
Autor:
Atilla Bozkurt, Mustafa Tugrul Goktas, Leyla Asena, Gulten Karabay, Yonca A. Akova, Umit Yasar, Ebru Demiralay
Publikováno v:
Current Eye Research. 38:472-479
This study was carried out to determine the ocular pharmacokinetics, efficacy and potential endothelial toxicity of moxifloxacin (MF) after a single intracameral bolus injection of 500 µg/0.1 ml in a rabbit model.Forty-eight eyes of 24 New Zealand W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4cc157f334a83b16093ca1fe307349
https://doi.org/10.3109/02713683.2012.763101
https://doi.org/10.3109/02713683.2012.763101
Autor:
Seref Can Gurel, Yavuz Ayhan, Cagatay Karaaslan, Hayriye Akel, Melih Babaoglu, Umit Yasar, Atilla Bozkurt, Nesrin Dilbaz, Berna Diclenur Ulug, Basaran Demir, R. Ozgur Karaca
Publikováno v:
Turk psikiyatri dergisi = Turkish journal of psychiatry. 27(2)
Previous investigations on opioid system genetics have identified polymorphisms of the OPRM1 gene expressing μ-opioid receptors to be significantly associated with some features of alcohol dependence (AD). In the present study, we evaluated the rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64621d1841ae4285f59371c81219ec57
https://pubmed.ncbi.nlm.nih.gov/27370058
https://pubmed.ncbi.nlm.nih.gov/27370058
Autor:
Cemal Bulut, Ali Pekcan Demiröz, Emine Fırat Göktaş, Erdem Kamil Ozer, Atilla Bozkurt, Ragip Ozgur Karaca, Sami Kinikli, Mustafa Tugrul Goktas
Publikováno v:
Canadian journal of microbiology. 62(7)
WOS: 000378785100009
PubMed: 27314608
The immunopathogenesis of chronic hepatitis B (CHB) has not been clarified yet. Toll-like receptors (TLR) are a receptor family that initiates immunity with exogenous-endogenous ligands and plays a role
PubMed: 27314608
The immunopathogenesis of chronic hepatitis B (CHB) has not been clarified yet. Toll-like receptors (TLR) are a receptor family that initiates immunity with exogenous-endogenous ligands and plays a role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a62c59408c40e26e64802608950f0f
https://pubmed.ncbi.nlm.nih.gov/27314608
https://pubmed.ncbi.nlm.nih.gov/27314608
Autor:
Umit Yasar, Atilla Bozkurt, Alpaslan Kilicarslan, Yildiz Yardimci, Melih O. Babaoglu, Gulay Sain-Guven
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 109:73-77
HMG-CoA reductase inhibitors (statins) have a potential to interact with substrates of the drug-metabolizing enzyme cytochrome P450 2C9 (CYP2C9). This may lead to concentration-dependent toxicity such as skeletal muscle side effects. Atorvastatin, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dc33f9d0003f74b99d8cb03a1f16e48
https://doi.org/10.1111/j.1742-7843.2011.00687.x
https://doi.org/10.1111/j.1742-7843.2011.00687.x