Výsledky vyhledávání - "Atilla Biçer"

Akademický článek

ChIP-Seq analysis identifies p27(Kip1)-target genes involved in cell adhesion and cell signalling in mouse embryonic fibroblasts.

Autor: Atilla Biçer, Serena Orlando, Abul B M M K Islam, Edurne Gallastegui, Arnaud Besson, Rosa Aligué, Oriol Bachs, Maria Jesús Pujol

Publikováno v: PLoS ONE, Vol 12, Iss 11, p e0187891 (2017)

The protein p27Kip1 (p27), a member of the Cip-Kip family of cyclin-dependent kinase inhibitors, is involved in tumorigenesis and a correlation between reduced levels of this protein in human tumours and a worse prognosis has been established. Recent

Externí odkaz: https://doaj.org/article/4ab105dde13a4f04bb5d87b0c6681c89

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The PxIxIT motif of the RCAN3 inhibits angiogenesis and tumor progression in Triple Negative breast cancer in immunocompetent mice

Autor: Atilla Biçer, Patricia López-Henares, Marta Molero-Magariño, Andrea Feu-Llauradó, Miguel Sabariego-Navarro, Sergi Bayod, Laura Padilla, Mª Rosario Taco, Sara Larriba, Mercè Pérez-Riba, Eva Serrano-Candelas

Publikováno v: Carcinogenesis. 43(8)

RCAN proteins are endogenous regulators of the calcineurin-cytosolic nuclear factor of activated T cells (CN-NFATc) pathway that bind CN through similar conserved motifs PxIxIT and LxVP of the NFATc family. RCAN1 and RCAN3 protein levels were reporte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9971385548bc340c9994e3a316d6bf3d
https://pubmed.ncbi.nlm.nih.gov/35640493

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Design and synthesis of a novel non peptide CN-NFATc signaling inhibitor for tumor suppression in triple negative breast cancer

Autor: Adrià Sánchez-Morales, Atilla Biçer, Vasilis Panagiotopoulos, Selma Crecente-Garcia, Cristina Benaiges, Sergi Bayod, José Luís Hernández, Félix Busqué, Minos-Timotheos Matsoukas, Mercè Pérez-Riba, Ramon Alibés

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona

Altres ajuts: acords transformatius de la UAB The Ca2/calmodulin-mediated phosphatase activity of calcineurin (CN) integrates calcium-mediated signaling with gene expression programs involved in the control of essential cellular processes in health a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f7e903465433fdac613febd8c5c101
http://hdl.handle.net/2445/188632

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Cis-trans proline isomers in the catalytic domain of calcineurin

Autor: Alicia Guasch, Álvaro Aranguren-Ibáñez, Mercè Pérez-Riba, Juan Carlos Paniagua, Ignacio Fita, Atilla Biçer, Saeed Chashmniam, João M.C. Teixeira, Miquel Pons

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Calcineurin is an essential calcium‐activated serine/threonine phosphatase. The six NMR‐observable methionine methyl groups in the catalytic domain of human calcineurin Aα (CNA) were assigned and used as reporters of the presence of potential ci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd8c6bf7e5f1dadb883893f9d7ef09a
http://hdl.handle.net/10261/201404

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p27Kip1 represses the Pitx2-mediated expression of p21Cip1 and regulates DNA replication during cell cycle progression

Autor: Maria Jesús Pujol, Oriol Bachs, Arnaud Besson, Atilla Biçer, Edurne Gallastegui, Serena Orlando

Publikováno v: Oncogene. 36:350-361

The tumor suppressor p21 regulates cell cycle progression and peaks at mid/late G1. However, the mechanisms regulating its expression during cell cycle are poorly understood. We found that embryonic fibroblasts from p27 null mice at early passages pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::760d480bbb95f4a2b72668520a854617
https://doi.org/10.1038/onc.2016.200

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ChIP-Seq analysis identifies p27(Kip1)-target genes involved in cell adhesion and cell signalling in mouse embryonic fibroblasts

Autor: Abul B. M. M. K. Islam, Edurne Gallastegui, Oriol Bachs, Atilla Biçer, Maria Jesús Pujol, Rosa Aligué, Arnaud Besson, Serena Orlando

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
PLoS ONE
Recercat. Dipósit de la Recerca de Catalunya
instname
PLoS ONE, Vol 12, Iss 11, p e0187891 (2017)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e88e2e27545f78cf1ca4a48f3fb9e6
http://hdl.handle.net/2445/118271

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Expression of platelet-derived growth factor ligand and receptor in cerebral arteriovenous and cavernous malformations

Autor: Ozlem Kurtkaya, Atilla Biçer, Ozlem Yildirim, Beyazid Cirakoglu, Abdulkadir Ozkan, Turker Kilic

Publikováno v: Journal of Clinical Neuroscience. 17:1557-1562

The aim of this study was to investigate the expression of platelet-derived growth factor (PDGF) ligands A and B and receptors α and β in cerebral arteriovenous and cavernous malformations. Fifteen arteriovenous malformation (AVM) and 15 cerebral c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba6c50279418980b3edc62060e5610a
https://doi.org/10.1016/j.jocn.2010.04.028

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Effect of Doxorubicin on Telomerase Activity and Apoptotic Gene Expression in Doxorubicin-Resistant and -Sensitive MCF-7 Cells

Autor: Ugur Eskiocak, Meltem Demirel Kars, Özlem Darcansoy İşeri, Atilla Biçer, Ufuk Gündüz

Publikováno v: Chemotherapy. 54:209-216

Background: Dose- and time-dependent effects of doxorubicin on telomerase activity (TA) and expression levels of hTERT, Bcl-2, Bcl-xL and Bax were investigated in doxorubicin-resistant and -sensitive MCF-7 cells. Methods: Doxorubicin-resistant MCF-7/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::af955ea10e239c212fb1d18c09daf643
https://doi.org/10.1159/000140464

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Expression of angiogenic factors in craniopharyngiomas: implications for tumor recurrence

Autor: Abdulkadir Ozkan, Demet Koc, Ozlem Kurtkaya, Turker Kilic, Süheyla Uyar Bozkurt, Halil Ibrahim Sun, M. Necmettin Pamir, Emel Akgun, Atilla Biçer

Publikováno v: Neurosurgery. 66(4)

BACKGROUND The primary treatment for craniopharyngiomas is total excision, but recurrence is common. However, current knowledge on the mechanisms of recurrence is limited. OBJECTIVE We hypothesized that recurrence is linked to the angiogenesis of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef8e83a954b6f049ec51af261137734
https://pubmed.ncbi.nlm.nih.gov/20190664

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Gamma knife radiosurgery for the treatment of glomus jugulare tumors

Autor: M. Necmettin Pamir, Ali Genc, Atilla Biçer, Turker Kilic, Ufuk Abacioglu, Selçuk Peker

Publikováno v: Journal of neuro-oncology. 97(1)

The treatment of glomus jugulare tumors represents a challenge for the neurosurgeon, since they invade major vessels and compress critical cranial nerves, resulting in significant morbidity from tumor resection. Among alternative and complementary tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987b11c807c4f151a253b5d2d8d345d6
https://pubmed.ncbi.nlm.nih.gov/19707722

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