Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Atif M. Nakhla"'
Publikováno v:
Journal of Endocrinology. 175:113-120
Sex hormone-binding globulin (SHBG) is a multifunctional protein that acts in humans to regulate the response to steroids at several junctures. It was originally described as a hepatically secreted protein that is the major binding protein for sex st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128605c2da2a6e19d61a489cd99840c0
https://doi.org/10.1677/joe.0.1750113
https://doi.org/10.1677/joe.0.1750113
Autor:
Victor D.-H. Ding, H.M. Saunders, Linda Rhodes, Atif M. Nakhla, Bill Pikounis, M S Khan, William Rosner, Ramon K. Kemp, William P. Feeney
Publikováno v:
The Prostate. 44:8-18
BACKGROUND Previous studies have shown that chronic treatment of castrate dogs with androgen and estrogen results in significant prostate growth. Estrogen treatment of castrate dogs in the absence of androgen has resulted in conflicting data as repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9baad77820a5cfbdf2e2a592633cd63
https://doi.org/10.1002/1097-0045(20000615)44:1<8::aid-pros2>3.0.co
https://doi.org/10.1002/1097-0045(20000615)44:1<8::aid-pros2>3.0.co
Publikováno v:
Steroids. 64:100-106
Androgens and estrogens are well-known to initiate their actions by binding to specific intracellular receptors. The steroid-receptor interaction, the receptors, and the details of transcriptional activation consequent to the binding of these steroid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c9742168e71c400cba4badce123112
https://doi.org/10.1016/s0039-128x(98)00108-1
https://doi.org/10.1016/s0039-128x(98)00108-1
Publikováno v:
Steroids. 63:278-281
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c9e11f77e0b54f42881c03547b854af
https://doi.org/10.1016/s0039-128x(98)00017-8
https://doi.org/10.1016/s0039-128x(98)00017-8
Autor:
Victor D.-H. Ding, Varsha Didolkar, Roy G. Smith, Linda Rhodes, David E. Moller, Atif M. Nakhla, William P. Feeney, William Rosner
Publikováno v:
Endocrinology. 139:213-218
Estradiol (E2) and 5alpha-androstan-3alpha,17beta-diol (3alpha-diol) have been implicated in prostate hyperplasia in man and dogs, but neither of these steroids bind to androgen receptors (ARs). Recently, we reported that E2 and 3alpha-diol stimulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e2f4544bd6cf8665954eea87d55f16
https://doi.org/10.1210/endo.139.1.5681
https://doi.org/10.1210/endo.139.1.5681
Publikováno v:
Journal of Biological Chemistry. 272:6838-6841
These experiments were designed to examine the relationship between the effects of steroid hormones mediated by classic intracellular steroid hormone receptors and those mediated by a signaling system subserved at the plasma membrane by a receptor fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d530ce76f7e3a9ee823a2cda4df76cb5
https://doi.org/10.1074/jbc.272.11.6838
https://doi.org/10.1074/jbc.272.11.6838
Autor:
Atif M. Nakhla, William Rosner
Publikováno v:
Endocrinology. 137:4126-4129
Sex hormone-binding globulin (SHBG) not only regulates the free concentration of certain steroid sex hormones in plasma, but is involved in a nongenomic mechanism of steroid hormone action. It binds to a receptor on prostatic cell membranes and is ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a67828cbbca3318c985bcaf76e58f38
https://doi.org/10.1210/endo.137.10.8828467
https://doi.org/10.1210/endo.137.10.8828467
Publikováno v:
Proceedings of the National Academy of Sciences. 91:5402-5405
Androgens are widely acknowledged to be central to the pathogenesis of benign prostatic hypertrophy (BPH). However, BPH increases in prevalence as men age, at precisely the stage of life when plasma androgens are decreasing. The decrease in total pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda85bda178110cca37b4a1c6493f9df
https://doi.org/10.1073/pnas.91.12.5402
https://doi.org/10.1073/pnas.91.12.5402
Publikováno v:
Molecular and cellular endocrinology. 316(1)
Sex hormone-binding globulin (SHBG) was initially described as a plasma protein synthesized in, and secreted by, the liver. It was discovered by its ability to bind certain androgens and estrogens and, for many years, was believed to serve as a trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c752e8ab274c0fea44c97359c180930d
https://pubmed.ncbi.nlm.nih.gov/19698759
https://pubmed.ncbi.nlm.nih.gov/19698759
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 40:813-820
Sex hormone-binding globulin (SHBG) is a plasma glycoprotein that binds a number of circulating steroid hormones (testosterone, dihydrotestosterone and estradiol) with high affinity, thus regulating their free concentration in plasma. In addition to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1e7a8b7304bb8558a4e68aa2ddfadf
https://doi.org/10.1016/0960-0760(91)90307-q
https://doi.org/10.1016/0960-0760(91)90307-q