Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Atif Ahmed Siddiqui"'
Autor:
Atif Ahmed Siddiqui, Emmanuelle Merquiol, Reut Bruck-Haimson, Joud Hirbawi, Hana Boocholez, Irit Cohen, Yonghong Yan, Meng Qiu Dong, Galia Blum, Ehud Cohen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract While the activities of certain proteases promote proteostasis and prevent neurodegeneration-associated phenotypes, the protease cathepsin B (CTSB) enhances proteotoxicity in Alzheimer’s disease (AD) model mice, and its levels are elevated
Externí odkaz:
https://doaj.org/article/e3c24ee5acc343fd87a60513d5ca45ab
Autor:
Manish Chamoli, Anita Goyala, Syed Shamsh Tabrez, Atif Ahmed Siddiqui, Anupama Singh, Adam Antebi, Gordon J. Lithgow, Jennifer L. Watts, Arnab Mukhopadhyay
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Metabolic reprogramming during Dietary Restriction (DR) activates cytoprotective gene expression. Here the authors show that PUFAs generated during DR signal via the p38-MAPK pathway to enhance cytoprotective gene expression, contributing to increase
Externí odkaz:
https://doaj.org/article/3c37c1fd9a7048f1bb216609bd91f5e7
Autor:
Hana Boocholez, Filipa Carvalhal Marques, Amir Levine, Noa Roitenberg, Atif Ahmed Siddiqui, Huadong Zhu, Lorna Moll, Danielle Grushko, Reut Bruck Haimson, Tayir Elami, Ehud Cohen
Publikováno v:
Cell Reports, Vol 38, Iss 6, Pp 110350- (2022)
Summary: The protein homeostasis (proteostasis) network (PN) encompasses mechanisms that maintain proteome integrity by controlling various biological functions. Loss of proteostasis leads to toxic protein aggregation (proteotoxicity), which underlie
Externí odkaz:
https://doaj.org/article/8b87583fd0624601b3339e66c187d358
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Alternative splicing coupled to nonsense-mediated decay (AS-NMD) is a conserved mechanism for post-transcriptional gene regulation. Here, the authors provide evidence that AS-NMD is enhanced during dietary restriction (DR) and is required for DR-medi
Externí odkaz:
https://doaj.org/article/f44c3f8b8fa7410ea1bd00d3f0cd9658
Autor:
Lorna Moll, Noa Roitenberg, Michal Bejerano-Sagie, Hana Boocholez, Filipa Carvalhal Marques, Yuli Volovik, Tayir Elami, Atif Ahmed Siddiqui, Danielle Grushko, Adi Biram, Bar Lampert, Hana Achache, Tommer Ravid, Yonatan B Tzur, Ehud Cohen
Publikováno v:
eLife, Vol 7 (2018)
Although aging-regulating pathways were discovered a few decades ago, it is not entirely clear how their activities are orchestrated, to govern lifespan and proteostasis at the organismal level. Here, we utilized the nematode Caenorhabditis elegans t
Externí odkaz:
https://doaj.org/article/b31f6b8500b049b2928dc3c11f46757c
Autor:
Hana Boocholez, Filipa Carvalhal Marques, Amir Levine, Noa Roitenberg, Atif Ahmed Siddiqui, Huadong Zhu, Lorna Moll, Danielle Grushko, Reut Bruck Haimson, Tayir Elami, Ehud Cohen
Publikováno v:
Cell Reports, Vol 38, Iss 6, Pp 110350-(2022)
Summary: The protein homeostasis (proteostasis) network (PN) encompasses mechanisms that maintain proteome integrity by controlling various biological functions. Loss of proteostasis leads to toxic protein aggregation (proteotoxicity), which underlie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81cda9b431bd4d871a1ec19c41e26e9d
https://pubmed.ncbi.nlm.nih.gov/35139369
https://pubmed.ncbi.nlm.nih.gov/35139369
Autor:
Manish Chamoli, Gordon J. Lithgow, Anita Goyala, Arnab Mukhopadhyay, Jennifer L. Watts, Syed Shamsh Tabrez, Anupama Singh, Adam Antebi, Atif Ahmed Siddiqui
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nat Commun
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nat Commun
The metabolic state of an organism instructs gene expression modalities, leading to changes in complex life history traits, such as longevity. Dietary restriction (DR), which positively affects health and life span across species, leads to metabolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a86a9a9c97ae5fc401ab94b0857b0ea
https://pubmed.ncbi.nlm.nih.gov/32978396
https://pubmed.ncbi.nlm.nih.gov/32978396
Autor:
Noa Roitenberg, Yuli Volovik, Danielle Grushko, Filipa Carvalhal Marques, Adi Biram, Atif Ahmed Siddiqui, Yonatan B Tzur, Tayir Elami, Michal Bejerano-Sagie, Hana Boocholez, Lorna Moll, Tommer Ravid, Hana Achache, Ehud Cohen, Bar Lampert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab36657bf8d81717229034fb90b3bf8b
https://doi.org/10.7554/elife.38635.035
https://doi.org/10.7554/elife.38635.035
Autor:
Adi Biram, Tayir Elami, Tommer Ravid, Danielle Grushko, Filipa Carvalhal Marques, Hana Achache, Yonatan B Tzur, Atif Ahmed Siddiqui, Noa Roitenberg, Hana Boocholez, Yuli Volovik, Lorna Moll, Michal Bejerano-Sagie, Ehud Cohen, Bar Lampert
Publikováno v:
eLife, Vol 7 (2018)
Although aging-regulating pathways were discovered a few decades ago, it is not entirely clear how their activities are orchestrated, to govern lifespan and proteostasis at the organismal level. Here, we utilized the nematode Caenorhabditis elegans t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2409f4279fec04da59f0b3e27053162
https://elifesciences.org/articles/38635
https://elifesciences.org/articles/38635