The cytotoxic activities of the major diterpene extracted from Salvia multicaulis (Bardakosh) are mediated by the regulation of heat-shock response and fatty acid metabolism pathways in human leukemia cells.

Autor: Nabih HK; National Research Centre, Medical Biochemistry Department, 33 El-Bohouth St., Dokki, Giza 12622, Egypt., Yücer R; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Staudinger Weg 5, 55128 Mainz, Germany., Mahmoud N; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Staudinger Weg 5, 55128 Mainz, Germany., Dawood M; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Staudinger Weg 5, 55128 Mainz, Germany; Department of Molecular Biology, Faculty of Medical Laboratory Science, Al-Neelain University, Khartoum, Sudan., Elbadawi M; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Staudinger Weg 5, 55128 Mainz, Germany., Shahhamzehei N; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Staudinger Weg 5, 55128 Mainz, Germany., Atia MAM; Molecular Genetics and Genome Mapping Laboratory, Genome Mapping Department, Agricultural Genetic Engineering Research Institute (AGERI), Agricultural Research Center (ARC), Giza 12619, Egypt., AbdelSadik A; Zoology Department, Faculty of Science, Aswan University, 81528 Aswan, Egypt; Molecular Biotechnology Program, Faculty of Advanced Basic Sciences, Galala University, 43552, New Galala, Egypt., Hussien TA; Pharmacognosy Department, Faculty of Pharmacy, Sphinx University, New Assiut City, Assiut 10, Egypt., Ibrahim MAA; Computational Chemistry Laboratory, Chemistry Department, Faculty of Science, Minia University, Minia 61519, Egypt; School of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban 4000, South Africa., Klauck SM; Division of Cancer Genome Research, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), and National Center for Tumor Diseases (NCT), Heidelberg, Germany., Hegazy MF; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Staudinger Weg 5, 55128 Mainz, Germany; National Research Centre, Chemistry of Medicinal Plants Department, 33 El-Bohouth St., Dokki, Giza 12622, Egypt. Electronic address: mohegazy@uni-mainz.de., Efferth T; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Staudinger Weg 5, 55128 Mainz, Germany. Electronic address: efferth@uni-mainz.de.

Publikováno v: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Sep 27; Vol. 135, pp. 156023. Date of Electronic Publication: 2024 Sep 27.

A new cembranoid from the Red Sea soft coral Sarcophyton acutum .

Autor: Mohamed TA; Chemistry of Medicinal Plants Dept, Chemistry of Medicinal Plants, Dokki, Giza, Egypt., Abdelmawgoud SM; Chemistry of Natural and Microbial Products Department, National Research Centre, Dokki, Giza, Egypt., Hamdy AA; Chemistry of Natural and Microbial Products Department, National Research Centre, Dokki, Giza, Egypt., Ibrahim MAA; Computational Chemistry Laboratory, Chemistry Department, Faculty of Science, Minia University, Minia, Egypt., Elshamy AI; Department of Natural Compounds Chemistry, National Research Centre, Dokki, Giza, Egypt., Atia MAM; Molecular Genetics and Genome Mapping Laboratory, Genome Mapping Department, Agricultural Genetic Engineering Research Institute (AGERI), ARC, Giza, Egypt., Kassem HA; Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt., Hegazy MF; Chemistry of Medicinal Plants Dept, Chemistry of Medicinal Plants, Dokki, Giza, Egypt., Selim NM; Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt.

Publikováno v: Natural product research [Nat Prod Res] 2024 Jan-Feb; Vol. 38 (3), pp. 512-522. Date of Electronic Publication: 2022 Oct 06.

Potential drug candidates as P-glycoprotein inhibitors to reverse multidrug resistance in cancer: an in silico drug discovery study.

Autor: Ibrahim MAA; Computational Chemistry Laboratory, Chemistry Department, Faculty of Science, Minia University, Minia, Egypt.; School of Health Sciences, University of KwaZulu-Natal, Westville, Durban, South Africa., Abdeljawaad KAA; Computational Chemistry Laboratory, Chemistry Department, Faculty of Science, Minia University, Minia, Egypt., Jaragh-Alhadad LA; Department of Chemistry, Faculty of Science, Kuwait University, Safat, Kuwait., Oraby HF; Deanship of Scientific Research, Umm Al-Qura University, Makkah, Saudi Arabia., Atia MAM; Molecular Genetics and Genome Mapping Laboratory, Genome Mapping Department, Agricultural Genetic Engineering Research Institute (AGERI), ARC, Giza, Egypt., Alzahrani OR; Department of Biology, Faculty of Sciences, University of Tabuk, Tabuk, Saudi Arabia., Mekhemer GAH; Computational Chemistry Laboratory, Chemistry Department, Faculty of Science, Minia University, Minia, Egypt., Moustafa MF; Department of Biology, College of Science, King Khalid University, Abha, Saudi Arabia.; Department of Botany and Microbiology, Faculty of Science, South Valley University, Qena, Egypt., Shawky AM; Science and Technology Unit (STU), Umm Al-Qura University, Makkah, Saudi Arabia., Sidhom PA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta, Egypt., Abdelrahman AHM; Computational Chemistry Laboratory, Chemistry Department, Faculty of Science, Minia University, Minia, Egypt.

Publikováno v: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2023; Vol. 41 (23), pp. 13977-13992. Date of Electronic Publication: 2023 Mar 08.

Anti-androgenic potential of the fruit extracts of certain Egyptian Sabal species and their genetic variability studies: a metabolomic-molecular modeling approach.

Autor: Abd Almaksoud HM; Department of Pharmacy, New Al Kaser Alini Hospital, Cairo, Egypt., El-Hawary SS; Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt. fatema.saber@pharma.cu.edu.eg., Atia MAM; Molecular Genetics and Genome Mapping Laboratory, Genome Mapping Department, Agricultural Genetic Engineering Research Institute (AGERI), Agricultural Research Center (ARC), Giza 12619, Egypt., Sayed AM; Department of Pharmacognosy, Faculty of Pharmacy, Nahda University, Beni-Suef 62513, Egypt., El-Daly M; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Minia University, El-Minia 61519, Egypt., Kamel AA; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Minia University, El-Minia 61519, Egypt., Elimam H; Department of Biochemistry, Faculty of Pharmacy, University of Sadat City, Sadat City 32897, Egypt.; Department of Biochemistry, Faculty of Pharmacy, Sinai University, Kantara, Egypt., Abdelmohsen UR; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt. Usama.ramadan@mu.edu.eg.; Department of Pharmacognosy, Faculty of Pharmacy, Deraya University, Universities Zone, 61111 New Minia City, Minia, Egypt., Saber FR; Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt. fatema.saber@pharma.cu.edu.eg.

Publikováno v: Food & function [Food Funct] 2022 Jul 18; Vol. 13 (14), pp. 7813-7830. Date of Electronic Publication: 2022 Jul 18.

Plant cell cultures: An enzymatic tool for polyphenolic and flavonoid transformations.

Autor: Mohamed TA; Chemistry of Medicinal Plants Department, National Research Centre, 33 El-Bohouth St., Dokki, Giza 12622, Egypt., Ali SK; Chemistry of Medicinal Plants Department, National Research Centre, 33 El-Bohouth St., Dokki, Giza 12622, Egypt., Elshamy AI; Natural Compounds Chemistry Department, National Research Centre, 33 El-Bohouth St., Dokki, Giza 12622, Egypt., Saleh IA; Chemistry of Medicinal Plants Department, National Research Centre, 33 El-Bohouth St., Dokki, Giza 12622, Egypt., Ibrahim MAA; Computational Chemistry Laboratory, Chemistry Department, Faculty of Science, Minia University, Minia 61519, Egypt., Atia MAM; Molecular Genetics and Genome Mapping Laboratory, Genome Mapping Department, Agricultural Genetic Engineering Research Institute (AGERI), Agricultural Research Center (ARC), Giza 12619, Egypt., Alshammari SO; Department of Biology, College of Science, University of Hafr Al Batin, Hafar Al Batin, Saudi Arabia., Mohamed AEH; Department of Chemistry, Faculty of Science, Aswan University, Aswan 81528, Egypt., Hussien TA; Pharmacognosy Department, Faculty of Pharmacy, Sphinx University, New Assiut City, Assiut 10, Egypt., Hamed AR; Chemistry of Medicinal Plants Department, National Research Centre, 33 El-Bohouth St., Dokki, Giza 12622, Egypt., Saedi HRE; Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm S-10691, Sweden; nternational Research Center for Food Nutrition and Safety, Jiangsu University, Zhenjiang 212013, China; Department of Chemistry, Faculty of Science, El-Menoufia University, Shebin El-Kom 32512, Egypt., Abdel-Azim NS; Chemistry of Medicinal Plants Department, National Research Centre, 33 El-Bohouth St., Dokki, Giza 12622, Egypt., Shams KA; Chemistry of Medicinal Plants Department, National Research Centre, 33 El-Bohouth St., Dokki, Giza 12622, Egypt., Efferth T; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Staudinger Weg 5, Mainz 55128, Germany. Electronic address: efferth@uni-mainz.de., Saker M; Genetic Engineering and Biotech. Division, National Research Centre, 33 El-Bohouth St., Dokki, Giza 12622, Egypt., Paré PW; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA., Hegazy MF; Chemistry of Medicinal Plants Department, National Research Centre, 33 El-Bohouth St., Dokki, Giza 12622, Egypt. Electronic address: mohegazy@uni-mainz.de.

Publikováno v: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2022 Jun; Vol. 100, pp. 154019. Date of Electronic Publication: 2022 Feb 27.