Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Athurva Gore"'
Autor:
Xingdong Chen, Jeffrey Gole, Athurva Gore, Qiye He, Ming Lu, Jun Min, Ziyu Yuan, Xiaorong Yang, Yanfeng Jiang, Tiejun Zhang, Chen Suo, Xiaojie Li, Lei Cheng, Zhenhua Zhang, Hongyu Niu, Zhe Li, Zhen Xie, Han Shi, Xiang Zhang, Min Fan, Xiaofeng Wang, Yajun Yang, Justin Dang, Catie McConnell, Juan Zhang, Jiucun Wang, Shunzhang Yu, Weimin Ye, Yuan Gao, Kun Zhang, Rui Liu, Li Jin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Patients whose disease is diagnosed in its early stages have better outcomes. In this study, the authors develop a non invasive blood test based on circulating tumor DNA methylation that can potentially detect cancer occurrence even in asymptomatic p
Externí odkaz:
https://doaj.org/article/f13abdef111b44f5aeede14fcb526903
Autor:
Grace Woodruff, Jessica E. Young, Fernando J. Martinez, Floyd Buen, Athurva Gore, Jennifer Kinaga, Zhe Li, Shauna H. Yuan, Kun Zhang, Lawrence S.B. Goldstein
Publikováno v:
Cell Reports, Vol 5, Iss 4, Pp 974-985 (2013)
Presenilin 1 (PS1) is the catalytic core of γ-secretase, which cleaves type 1 transmembrane proteins, including the amyloid precursor protein (APP). PS1 also has γ-secretase-independent functions, and dominant PS1 missense mutations are the most co
Externí odkaz:
https://doaj.org/article/b6163cb80f724d8a9252a7d182cc3f52
Autor:
Xiaorong Yang, Yajun Yang, Zhenhua Zhang, Rui Liu, Athurva Gore, Ziyu Yuan, Yuan Gao, Zhen Xie, Kun Zhang, Zhe Li, Chen Suo, Xiaojie Li, Min Fan, Yanfeng Jiang, He Qiye, Li Jin, Xiaofeng Wang, Xingdong Chen, Hongyu Niu, Juan Zhang, Tiejun Zhang, Weimin Ye, Catie McConnell, Ming Lu, Jun Min, Justin Dang, Shun-Zhang Yu, Jeffrey A. Gole, Jiucun Wang, Lei Cheng, Han Shi, Xiang Zhang
Publikováno v:
Nature communications, vol 11, iss 1
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Early detection has the potential to reduce cancer mortality, but an effective screening test must demonstrate asymptomatic cancer detection years before conventional diagnosis in a longitudinal study. In the Taizhou Longitudinal Study (TZL), 123,115
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71fa5e72715a251ee130ead4dc62f8f5
https://escholarship.org/uc/item/35f8h6p9
https://escholarship.org/uc/item/35f8h6p9
Autor:
Zhe Li, Athurva Gore, Zhoufeng Wang, Jun Min, Jeffrey A. Gole, Jingyi Lu, Kun Zhang, Weimin Li, Rui Liu, Yuan Gao
Publikováno v:
Journal of Clinical Oncology. 37:e13159-e13159
e13159 Background: Lung cancer is one of the most common forms of cancer and is responsible for approximately 1.8 million deaths per year worldwide. The current 5-year survival rate for lung cancer is only 18%; however, this improves to 56% if the ca
Autor:
John Aach, Euan A. Ashley, Je-Hyuk Lee, Hugh Y. Rienhoff, Matthew T. Wheeler, Jong Bhak, Peter J. Hulick, Joyce L. Yang, Carlos Cano, Radoje Drmanac, Jeong-Sun Seo, Jong Il Kim, Athurva Gore, Anugraha M. Raman, Zhe Li, Xiaodi Wu, Shawn M. Douglas, Michael F. Chou, Daniel B. Vorhaus, Jin Billy Li, Alberto Labarga, Michael F. Murray, Kimberly Robasky, Seong-Jin Kim, Byung Chul Kim, Leonid Peshkin, Luhan Yang, George M. Church, Misha Angrist, Joseph V. Thakuria, Preston W. Estep, Jeantine E. Lunshof, Christine E. Seidman, Madeleine Ball, Tom Clegg, Alexander Wait Zaranek, Abraham M. Rosenbaum, Brock A. Peters, Wendy K. Chung, Ward Vandewege, Heidi L. Rehm, Geoffrey B. Nilsen, Matthew J. Callow, Kun Zhang, Jason Bobe
Publikováno v:
Ball, M P, Thakuria, J V, Zaranek, A W, Clegg, T, Rosenbaum, A M, Wu, X, Angrist, M, Bhak, J, Bobe, J, Callow, M J, Cano, C, Chou, M F, Chung, W K, Douglas, S M, Estep, P W, Gore, A, Hulick, P, Labarga, A, Lee, J-H, Lunshof, J E, Kim, B C, Kim, J L, Li, Z, Murray, M F, Nilsen, G B, Peters, B A, Raman, A M, Rienhoff, H Y, Robasky, K, Wheeler, M T, Vandewege, W, Vorhaus, D B, Yang, Y L, Yang, L, Aach, J, Ashley, E A, Drmanac, R, Kim, S-J, Li, J B, Peshkin, L, Seidman, S E, Seo, J-S, Zhang, K, Rehm, H L & Church, G M 2012, ' A public resource facilitating clinical use of genomes. ', Proceedings of the National Academy of Sciences of the United States of America, vol. 109, no. 30, pp. 11920-11927 . https://doi.org/10.1073/pnas.1201904109
Proceedings of the National Academy of Sciences of the United States of America, 109(30), 11920-11927. National Acad Sciences
Proceedings of the National Academy of Sciences of the United States of America, 109(30), 11920-11927. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, vol 109, iss 30
Proceedings of the National Academy of Sciences of the United States of America, 109(30), 11920-11927. National Acad Sciences
Proceedings of the National Academy of Sciences of the United States of America, 109(30), 11920-11927. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, vol 109, iss 30
Rapid advances in DNA sequencing promise to enable new diagnostics and individualized therapies. Achieving personalized medicine, however, will require extensive research on highly reidentifiable, integrated datasets of genomic and health information
Autor:
Richard A. Lewis, Xianfeng Chen, Richard A. Gibbs, Athurva Gore, Ming Cao, Kun Zhang, Hui Wang, Donna M. Muzny, Ali A. Al-Rajhi, Graeme Mardon, Zhe Li, James R. Lupski, Rui Chen, Emad B. Abboud, Xia Wang, Claire Patenia
Publikováno v:
Human Mutation. 32:1450-1459
It has been well documented that mutations in the same retinal disease gene can result in different clinical phenotypes due to difference in the mutant allele and/or genetic background. To evaluate this, a set of consanguineous patient families with
Publikováno v:
Cancer Research. 78:3249-3249
Low-dose computed tomography (LDCT) is recommended for early lung cancer screening in high-risk populations. Small lung nodules are identified by these CT scans in up to 50% of high-risk patients. While over 50% of lung nodules less than 1 cm are ben
Autor:
Junying Yu, In-Hyun Park, Emily M LeProust, Kun Zhang, Dieter Egli, Yuan Gao, James A. Thomson, Athurva Gore, Kevin Eggan, George Q. Daley, Nimet Maherali, Bin Xie, Jessica Antosiewicz-Bourget, Konrad Hochedlinger, Wei Li Wang, Jie Deng, Robert Shoemaker
Publikováno v:
Nature Biotechnology. 27:353-360
Current DNA methylation assays are limited in the flexibility and efficiency of characterizing a large number of genomic targets. We report a method to specifically capture an arbitrary subset of genomic targets for single-molecule bisulfite sequenci
Autor:
Athurva Gore, Xiaoliang Lan, Jun Min, Li Liang, John Duc Nguyen, Sufen Zhang, Rui Liu, Xiaojie Liu, Zi Qin
Publikováno v:
Journal of Clinical Oncology. 35:e13003-e13003
e13003 Background: Recurrent somatic mutations and methylation patterns have previously been identified as biomarkers for non-invasive screening of colorectal cancer (CRC). However, most clinical screening assays have focused on a limited number of g
Autor:
Hong Ma, Nanfang Xu, Athurva Gore, Shoukhrat Mitalipov, Zhe Li, Tamar Golan-Lev, Ido Sagi, Yufeng Shen, Mitsutoshi Yamada, Mark V. Sauer, Bjarki Johannesson, Daniel Paull, Charles A. LeDuc, Nissim Benvenisty, Samantha Stern, Eunju Kang, Kun Zhang, Dieter Egli
Publikováno v:
Cell stem cell. 15(5)
SummaryThe recent finding that reprogrammed human pluripotent stem cells can be derived by nuclear transfer into human oocytes as well as by induced expression of defined factors has revitalized the debate on whether one approach might be advantageou