Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Athulaprabha Murthi"'
Autor:
Andrea B. Keefer, Athulaprabha Murthi, Susan Gottesman, Zonglin Hu, Stephen H. Leppla, Aurelie Tomczak, Rodolfo Ghirlando, Apostolos G. Gittis, David N. Garboczi, Catherine E. Vrentas
Publikováno v:
Protein Science. 24:1808-1819
Hfq proteins in Gram-negative bacteria play important roles in bacterial physiology and virulence, mediated by binding of the Hfq hexamer to small RNAs and/or mRNAs to post-transcriptionally regulate gene expression. However, the physiological role o
Autor:
Tsung Po Lai, Hsiao-Yun Huang, Anita K. Hopper, Hussam H. Shaheen, Athulaprabha Murthi, Eric M. Phizicky, Melanie A. Preston
Publikováno v:
Molecular Biology of the Cell
tRNAs traffic between the nucleus and the cytoplasm in response to nutrient availability. Using a new assay to track tRNA within cells, we show that tRNA nuclear import is constitutive, whereas tRNA reexport to the cytoplasm is regulated. Msn5 functi
Autor:
Gang Peng, Athulaprabha Murthi, Anita K. Hopper, Tsung Po Lai, Karen A. Stauffer, Nancy C. Martin, Hussam H. Shaheen
Publikováno v:
Traffic. 10:1243-1256
Trm1 is a tRNA specific m(2)(2)G methyltransferase shared by nuclei and mitochondria in Saccharomyces cerevisiae. In nuclei, Trm1 is peripherally associated with the inner nuclear membrane (INM). We investigated the mechanism delivering/tethering Trm
Autor:
Anita K. Hopper, Leonard S. Jefferson, Athulaprabha Murthi, Scot R. Kimball, Hussam H. Shaheen, Rick L. Horetsky
Publikováno v:
Proceedings of the National Academy of Sciences. 104:8845-8850
Until recently, transport of tRNA was presumed to be unidirectional, from the nucleus to the cytoplasm. Our published findings, however, revealed that cytoplasmic tRNAs move retrograde to the nucleus in Saccharomyces cerevisiae and that nuclear accum
Autor:
Athulaprabha Murthi, Anita K. Hopper
Publikováno v:
Genetics. 170:1553-1560
Appropriate nuclear membrane structure is important for all eukaryotic organisms as evidenced by the numerous human diseases and alterations in gene expression caused by inappropriate targeting of proteins to the inner nuclear membrane (INM). We repo