Structural mechanism of bridge RNA-guided recombination.

Autor: Hiraizumi M; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan., Perry NT; Arc Institute, Palo Alto, CA, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; San Francisco Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA, USA., Durrant MG; Arc Institute, Palo Alto, CA, USA., Soma T; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan., Nagahata N; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan., Okazaki S; Structural Biology Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan., Athukoralage JS; Arc Institute, Palo Alto, CA, USA., Isayama Y; Structural Biology Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan., Pai JJ; Arc Institute, Palo Alto, CA, USA., Pawluk A; Arc Institute, Palo Alto, CA, USA., Konermann S; Arc Institute, Palo Alto, CA, USA.; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA., Yamashita K; Structural Biology Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan., Hsu PD; Arc Institute, Palo Alto, CA, USA. patrick@arcinstitute.org.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA. patrick@arcinstitute.org.; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA. patrick@arcinstitute.org., Nishimasu H; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan. nisimasu@g.ecc.u-tokyo.ac.jp.; Structural Biology Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan. nisimasu@g.ecc.u-tokyo.ac.jp.; Inamori Research Institute for Science, Kyoto, Japan. nisimasu@g.ecc.u-tokyo.ac.jp.

Publikováno v: Nature [Nature] 2024 Jun; Vol. 630 (8018), pp. 994-1002. Date of Electronic Publication: 2024 Jun 26.

Bridge RNAs direct modular and programmable recombination of target and donor DNA.

Autor: Durrant MG; Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA., Perry NT; Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; University of California, Berkeley - University of California, San Francisco Graduate Program in Bioengineering, Berkeley, CA, USA., Pai JJ; Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA., Jangid AR; Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA., Athukoralage JS; Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA., Hiraizumi M; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan., McSpedon JP; Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA., Pawluk A; Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA., Nishimasu H; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.; Structural Biology Division, Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan.; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.; Inamori Research Institute for Science, 620 Suiginya-cho, Shimogyo-ku, Kyoto 600-8411, Japan.; Japan Science and Technology Agency, Core Research for Evolutional Science and Technology, 4-1-8, Honcho, Kawaguchi-shi, Saitama 332-0012, Japan., Konermann S; Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA.; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA., Hsu PD; Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA.; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jan 26. Date of Electronic Publication: 2024 Jan 26.

Bacteriophages inhibit and evade cGAS-like immune function in bacteria.

Autor: Huiting E; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA., Cao X; Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing Key Laboratory of Bioprocess, State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China., Ren J; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Ministry of Agriculture, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100081, China., Athukoralage JS; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA., Luo Z; Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing Key Laboratory of Bioprocess, State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China., Silas S; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA., An N; Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing Key Laboratory of Bioprocess, State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China., Carion H; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA., Zhou Y; National Institute of Biological Sciences, Beijing 102206, China., Fraser JS; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158, USA., Feng Y; Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing Key Laboratory of Bioprocess, State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China. Electronic address: fengyue@mail.buct.edu.cn., Bondy-Denomy J; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA; Quantitative Biosciences Institute, University of California, San Francisco, San Francisco, CA 94158, USA; Innovative Genomics Institute, Berkeley, CA 94720, USA. Electronic address: joseph.bondy-denomy@ucsf.edu.

Publikováno v: Cell [Cell] 2023 Feb 16; Vol. 186 (4), pp. 864-876.e21. Date of Electronic Publication: 2023 Feb 06.

Cyclic oligoadenylate signalling and regulation by ring nucleases during type III CRISPR defence.

Autor: Athukoralage JS; University of St Andrews jsa8@st-andrews.ac.uk., White MF; University of St Andrews.

Publikováno v: RNA (New York, N.Y.) [RNA] 2021 May 13. Date of Electronic Publication: 2021 May 13.

Fuse to defuse: a self-limiting ribonuclease-ring nuclease fusion for type III CRISPR defence.

Autor: Samolygo A; Skolkovo Institute of Science and Technology, Bolshoy Boulevard, 30/1, Moscow 121205, Russian Federation.; Biomedical Sciences Research Complex, School of Biology, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, UK., Athukoralage JS; Biomedical Sciences Research Complex, School of Biology, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, UK., Graham S; Biomedical Sciences Research Complex, School of Biology, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, UK., White MF; Biomedical Sciences Research Complex, School of Biology, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, UK.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2020 Jun 19; Vol. 48 (11), pp. 6149-6156.