Mycophenolate and azathioprine efficacy in interstitial lung disease: a systematic review and meta-analysis

Autor: Sally Singh, Mark Jones, Michael Kreuter, Maria Molina-Molina, Imre Noth, Andrew Wilson, Martin Brutsche, Naftali Kaminski, Gary M Hunninghake, Michael Keane, Nazia Chaudhuri, Ian Forrest, Bruno Crestani, Fernando J Martinez, Mohsen Sadatsafavi, Luca Richeldi, Antje Prasse, Fasihul Khan, Iain Stewart, Steve Jones, Gisli Jenkins, Gauri Saini, David Turner, Killian Hurley, Lucilla Piccari, Andrew Palmer, Joseph A Lasky, Simon Hart, Joyce Lee, Anthony Gordon, John Blaikley, Kirsty Hett, Helmut Prosch, Elisabeth Bendstrup, Christopher Huntley, Helen Parfrey, Huzaifa Adamali, Paul Beirne, Stephen Bianchi, George Chalmers, Sophie Fletcher, Peter George, Michael Gibbons, Mark Spears, Laura Fabbri, Felix Chua, Michael Henry, Cormac McCarthy, Sabrina Paganoni, Joseph Jacob, Mark Toshner, Bibek Gooptu, Andrew Briggs, Philip L Molyneaux, Athol Wells, Charlotte Summers, Leticia Kawano-Dourado, Ian Glaspole, Melanie Quintana, Christopher J Ryerson, Paolo Spagnolo, Francesco Bonella, Carisi Anne Polanczyk, Anjali Crawshaw, Laurence Pearmain, Avinash Anil Nair, Raphaël Borie, Alexandre Biasi Cavalcanti, Emanuela Falaschetti, Jonathan Chung, James Eaden, Kate Johnson, Shaney Barratt, Chris Ryerson, Juergen Behr, Andreas Guenther, Nik Hirani, Karin Storrer, Deepak Talwar, Claudia Ravaglia, Katerina Antoniou, Sara Freitas, Carlo Vancheri, Laura Price, Amanda Goodwin, Daniel Chambers, Gunnar Gudmundsson, Roger Lewis, Ingrid Cox, Anne Holland, Erica Farrand, Argyrios Tzouvelekis, Rui Rolo, Duncan Richards, Larissa Schwarzkopf, Sabina Guler, Devesh Dhasmana, Claudia Valenzuela, John S Kim, Louise Crowley, Lisa Watson, Amanda Bravery, Elisabetta Balestro, Wendy Adams, Francesco Lombardi, Ali Mojibian, Ana Etges, Ana Sousa Marcelino Boshoff, Anne Bergeron Anna-MariaHoffmann-Vold, Athina Trachalaki, Barbara Wendelberger, Bhavika Kaul Ben Hope-Gill, Bruno Baldi, Carlos Robalo, Chris Grainge, Christophe von Garnier, Conal Hayton, Dapeng Wang, Daphne Bablis, David Thicket, Deji Adegunsoye, Devaraj Anand, Dhruv Parek, Diane Griffiths, Eliana Santucci, Eliza Tsitoura, Emma Karlsen, Ena Gupta, Harold Collard, Hernan Fainberg, Iazsmin Bauer-Ventura, Irina Strambu, Jacobo Sellares, Janet Johnston, Jeff Swigris, Karina Negrelli, Katarzyna Lewandowska, Katrin Hostettler, Kerri Johannson, Liam Galvin, Lisa G. Spencer, Manuela Funke Chambour, Marlies Wijsenbeek-Lourens, Martina Vasakova, Milena Man Iuliu Hatieganu, Nick Weatherley, Ovidiu Fira Mladinescu Victor Babes, Peter Bryce, Pilar Rivera Ortega, Radu Crisan-Dabija, Rahul Maida, Sara Piciucchi, Shama Malik, Simone Dal Corso, Stefan Stanel

Publikováno v: BMJ Open Respiratory Research, Vol 11, Iss 1 (2024)

Objectives Mycophenolate mofetil (MMF) and azathioprine (AZA) are immunomodulatory treatments in interstitial lung disease (ILD). This systematic review aimed to evaluate the efficacy of MMF or AZA on pulmonary function in ILD.Design Population inclu

Externí odkaz: https://doaj.org/article/2ac47dada7d648a4a2a2a9b8b2f6ab10

Pharmacological and nonpharmacological interventions to improve symptom control, functional exercise capacity and quality of life in interstitial lung disease: an evidence synthesis

Autor: Sabrina Bajwah, Jill Colquitt, Emma Loveman, Claudia Bausewein, Howard Almond, Adejoke Oluyase, Mendy Dzingina, Matthew Maddocks, Irene J. Higginson, Athol Wells

Publikováno v: ERJ Open Research, Vol 7, Iss 1 (2021)

We assessed efficacy and effectiveness of pharmacological and nonpharmacological interventions in improving symptom control, functional exercise capacity and quality of life (QoL) in people living with fibrotic interstitial lung disease (ILD). We sum

Externí odkaz: https://doaj.org/article/86a6174f3efa49609ca7559ed722a74c

The European IPF registry (eurIPFreg): baseline characteristics and survival of patients with idiopathic pulmonary fibrosis

Autor: Andreas Guenther, Ekaterina Krauss, Silke Tello, Jasmin Wagner, Bettina Paul, Stefan Kuhn, Olga Maurer, Sabine Heinemann, Ulrich Costabel, María Asunción Nieto Barbero, Veronika Müller, Philippe Bonniaud, Carlo Vancheri, Athol Wells, Martina Vasakova, Alberto Pesci, Matteo Sofia, Walter Klepetko, Werner Seeger, Fotios Drakopanagiotakis, Bruno Crestani

Publikováno v: Respiratory Research, Vol 19, Iss 1, Pp 1-10 (2018)

Abstract Background Since 2009, IPF patients across Europe are recruited into the eurIPFreg, providing epidemiological data and biomaterials for translational research. Methods The registry data are based on patient and physician baseline and follow-

Externí odkaz: https://doaj.org/article/fd881de11e4b4df48f8920e0300262e4

Machine learning in radiology: the new frontier in interstitial lung diseases

Autor: Hayley, Barnes, Stephen M, Humphries, Peter M, George, Deborah, Assayag, Ian, Glaspole, John A, Mackintosh, Tamera J, Corte, Marilyn, Glassberg, Kerri A, Johannson, Lucio, Calandriello, Federico, Felder, Athol, Wells, Simon, Walsh

Publikováno v: The Lancet Digital Health. 5:e41-e50

Challenges for the effective management of interstitial lung diseases (ILDs) include difficulties with the early detection of disease, accurate prognostication with baseline data, and accurate and precise response to therapy. The purpose of this Revi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29a2f7287bbb73734f27d70ab3c8802
https://doi.org/10.1016/s2589-7500(22)00230-8

Communication difficulties reported by patients diagnosed with idiopathic pulmonary fibrosis and their carers: a European focus group study

Autor: Sarah Masefield, Nicola Cassidy, Derek Ross, Pippa Powell, Athol Wells

Publikováno v: ERJ Open Research, Vol 5, Iss 2 (2019)

This paper explores commonalities in the experience and unmet needs of idiopathic pulmonary fibrosis (IPF) patients and carers in Europe throughout the care pathway, focusing specifically on the unmet communication needs of patients and carers. Four

Externí odkaz: https://doaj.org/article/e94a20ddfe2f4db38978688b399154ca