Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Athina Paterou"'
Publikováno v:
PLoS Pathogens, Vol 5, Iss 2, p e1000317 (2009)
The genome of Trypanosoma brucei is unusual in being regulated almost entirely at the post-transcriptional level. In terms of regulation, the best-studied genes are procyclins, which encode a family of major surface GPI-anchored glycoproteins (EP1, E
Externí odkaz:
https://doaj.org/article/09fafc9656da491ea70d701fbbfd7e77
African trypanosomes are medically important parasites that cause Sleeping sickness in humans and nagana in animals. In addition to their pathogenic role, they have emerged as valuable model organisms for studying fundamental biological processes. Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43212ac54255f0bbe2a61e28decee345
https://doi.org/10.1101/2023.04.21.537815
https://doi.org/10.1101/2023.04.21.537815
Autor:
Arcadio Rubio García, Athina Paterou, Rebecca D. Powell Doherty, Laurie G. Landry, Mercede Lee, Amanda M. Anderson, Hubert Slawinski, Ricardo C. Ferreira, Dominik Trzupek, Agnieszka Szypowska, Linda S. Wicker, Luc Teyton, Nicola Ternette, Maki Nakayama, John A. Todd, Marcin L. Pekalski
Type 1 diabetes (T1D) is caused by a T-cell-mediated destruction of insulin-secreting pancreatic islet β cells. The T1D-predisposing human leukocyte antigen (HLA) class II molecule, DQ8, binds and presents insulin B chain peptides in the thymus prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::088d2857e527d780bc0ac671af83e408
https://doi.org/10.1101/2022.05.11.22274678
https://doi.org/10.1101/2022.05.11.22274678
Autor:
Arcadio Rubio García, Mercede Lee, Laurie G. Landry, Hubert Sławiński, Dominik Trzupek, John A. Todd, Maki Nakayama, Luc Teyton, Marcin Ł. Pękalski, Ricardo C. Ferreira, Athina Paterou, Agnieszka Szypowska, Linda S. Wicker
Type 1 diabetes (T1D) is a common autoimmune disorder characterized by the destruction of insulin-secreting pancreatic β cells [1], in which polymorphism of the human leukocyte antigen (HLA) class II region is the major genetic risk factor [2, 3, 4]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ce1a8c72db764d6107365947f420f72
https://doi.org/10.1101/2021.09.06.458974
https://doi.org/10.1101/2021.09.06.458974
Autor:
Mercede Lee, Linda S. Wicker, Athina Paterou, Marcin Ł. Pękalski, Arcadio Rubio García, John A. Todd, Hubert Sławiński
How organisms achieve sustained peripheral tolerance throughout their lifetime, a correct immune discrimination between self and non-self, remains poorly understood. Host-microbiome interactions carry fundamental information that facilitates this pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd5ca7bbcf7433ea69ae6ebadebbd3d2
https://doi.org/10.1101/2019.12.18.881433
https://doi.org/10.1101/2019.12.18.881433
Autor:
Juliane Schroeder, Toni Aebischer, Daniel Paape, Martin E. Barrios-Llerena, Athina Paterou, Geo Semini
Publikováno v:
MicrobiologyOpen
Leishmania spp. are protozoan parasites that are transmitted by sandfly vectors during blood sucking to vertebrate hosts and cause a spectrum of diseases called leishmaniases. It has been demonstrated that host cholesterol plays an important role dur
Publikováno v:
Trends in Parasitology. 20:40-47
Preventing the transmission of African trypanosomes between mammalian hosts has been one of the most effective mechanisms to date for the control of these important parasites. Hence, understanding the mechanisms through which they control their life
Autor:
Christoph Lippuner, Janko Brand, Daniel Paape, Melville Richardson, Kirstin Hoffmann, Volker Brinkmann, Toni Aebischer, Andrew J.H. Smith, C. Clare Blackburn, Athina Paterou
Publikováno v:
Lippuner, C, Paape, D, Paterou, A, Brand, J, Richardson, M, Smith, A, Hoffmann, K, Brinkmann, V, Blackburn, C & Aebischer, T 2009, ' Real-time imaging of Leishmania mexicana-infected early phagosomes: a study using primary macrophages generated from green fluorescent protein-Rab5 transgenic mice ', The FASEB Journal, vol. 23, no. 2, pp. 483-491 . https://doi.org/10.1096/fj.08-108712
The small GTPase Rab5 is a key regulator of endosome/phagosome maturation and in intravesicular infections marks a phagosome stage at which decisions over pathogen replication or destruction are integrated. It is currently unclear whether Leishmania-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f2ed0c17541bb43060c2ffb7bb517f
https://www.pure.ed.ac.uk/ws/files/8407160/faseb_2009_Blackburn.pdf
https://www.pure.ed.ac.uk/ws/files/8407160/faseb_2009_Blackburn.pdf
Publikováno v:
Paterou, A, Walrad, P, Craddy, P, Fenn, K & Matthews, K 2006, ' Identification and stage-specific association with the translational apparatus of TbZFP3, a CCCH protein that promotes trypanosome life-cycle development ', Journal of Biological Chemistry, vol. 281, no. 51, pp. 39002-13 . https://doi.org/10.1074/jbc.M604280200
The post-transcriptional control of gene expression is becoming increasingly important in the understanding of regulated events in eukaryotic cells. The parasitic kinetoplastids have a unique reliance on such processes, because their genome is organi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f70f18e1e782cadfbcbdad5fea0de30
https://europepmc.org/articles/PMC2688685/
https://europepmc.org/articles/PMC2688685/