Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Athina Georgiadou"'
Autor:
Athina Georgiadou, Claire Dunican, Pablo Soro-Barrio, Hyun Jae Lee, Myrsini Kaforou, Aubrey J Cunnington
Publikováno v:
eLife, Vol 11 (2022)
Recent initiatives to improve translation of findings from animal models to human disease have focussed on reproducibility but quantifying the relevance of animal models remains a challenge. Here, we use comparative transcriptomics of blood to evalua
Externí odkaz:
https://doaj.org/article/0bb960023260409f9cc41db06930ed8c
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Acute kidney injury (AKI) is a common feature of severe malaria, and an independent risk factor for death. Previous research has suggested that an overactivation of the host inflammatory response is at least partly involved in mediating the kidney da
Externí odkaz:
https://doaj.org/article/ecb748b9db604eb5b6737e6d07478b27
Autor:
Athina Georgiadou, Praveena Naidu, Sophie Walsh, Steve Kamiza, Valentina Barrera, Simon P Harding, Christopher A Moxon, Aubrey J Cunnington
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 4, Pp n/a-n/a (2021)
Abstract Objective Cerebral malaria (CM) is a complication of Plasmodium falciparum malaria, in which progressive brain swelling is associated with sequestration of parasites and impaired barrier function of the cerebral microvascular endothelium. To
Externí odkaz:
https://doaj.org/article/04c405dea18a4403bd151336f37fe056
Autor:
Valentina Barrera, Sophie Walsh, Praveena Naidu, Athina Georgiadou, Aubrey J. Cunnington, Christopher A. Moxon, Simon P. Harding, Steve Kamiza
Publikováno v:
CLINICAL & TRANSLATIONAL IMMUNOLOGY
Clinical & Translational Immunology, Vol 10, Iss 4, Pp n/a-n/a (2021)
Clinical & Translational Immunology
Clinical & Translational Immunology, Vol 10, Iss 4, Pp n/a-n/a (2021)
Clinical & Translational Immunology
Objective Cerebral malaria (CM) is a complication of Plasmodium falciparum malaria, in which progressive brain swelling is associated with sequestration of parasites and impaired barrier function of the cerebral microvascular endothelium. To test the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cc829a400a7eefa47b04e22846246d
Publikováno v:
FYSIKOTHERAPIA. 23
Aim: To record the effects of AN-t on the body growth and function of the cardiovascular and respiratory system of preterm infants during the first 5 days period of the study. Material - Method: 24 preterm infant, with gestational age ≤ 32 weeks(af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54f01177912ac284ff1b4503bc55cf13
https://doi.org/10.55742/txno7300
https://doi.org/10.55742/txno7300
Autor:
Shakil Ahmad, Keqing Wang, Thamir M. Ismail, Ankana Ganguly, Stephane R. Gross, Maral Ebrahimzadeh Asl Tabrizi, Jayna J. Mistry, Tara L. Lancaster, Philip S. Rudland, Athina Georgiadou
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-18 (2018)
SCIENTIFIC REPORTS
Scientific Reports
SCIENTIFIC REPORTS
Scientific Reports
S100P has been shown to be a marker for carcinogenesis where its expression in solid tumours correlates with metastasis and a poor patient prognosis. This protein’s role in any physiological process is, however, unknown. Here we first show that S10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c00058722658b06c5201dc2439c0d64
http://link.springer.com/article/10.1038/s41598-018-29852-2
http://link.springer.com/article/10.1038/s41598-018-29852-2
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background Interactions between the endothelium and infected erythrocytes play a major role in the pathogenesis of falciparum malaria, with microvascular dysfunction and parasite sequestration associated with worsening outcomes. The glycocalyx is a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a72f858ddd283919ed33563abc9d2a7
https://doi.org/10.1093/cid/ciz043
https://doi.org/10.1093/cid/ciz043
Autor:
Evelin Schwarzer, Bärbel Raupach, Jean Langhorne, Valentina Barrera, Sebastian Lorenz Knackstedt, Simon P. Harding, Christopher A. Moxon, Deirdre Cunningham, Sam Patel, Renate Krüger, Aase Berg, Volker Brinkmann, Falko Apel, Kari Otterdal, Borko Amulic, Benjamin Mordmüller, Athina Georgiadou, Aubrey J. Cunnington, Ulrike Abu-Abed, Arturo Zychlinsky
Publikováno v:
Knackstedt, S L, Georgiadou, A, Apel, F, Abu-Abed, U, Moxon, C A, Cunnington, A J, Raupach, B, Cunningham, D, Langhorne, J, Krüger, R, Barrera, V, Harding, S P, Berg, A, Patel, S, Otterdal, K, Mordmüller, B, Schwarzer, E, Brinkmann, V, Zychlinsky, A & Amulic, B 2019, ' Neutrophil extracellular traps drive inflammatory pathogenesis in malaria ', Science Immunology, vol. 4, no. 40, eaaw0336 . https://doi.org/10.1126/sciimmunol.aaw0336
SCIENCE IMMUNOLOGY
Science Immunology
SCIENCE IMMUNOLOGY
Science Immunology
Neutrophils are essential innate immune cells that extrude chromatin in the form of neutrophil extracellular traps (NETs) when they die. This form of cell death has potent immunostimulatory activity. We show that heme-induced NETs are essential for m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8690c8d7c84f48f18692ecb1587269
https://research-information.bris.ac.uk/ws/files/214087360/all_revisions_no_track_changes_03062019_SUBMITTED.pdf
https://research-information.bris.ac.uk/ws/files/214087360/all_revisions_no_track_changes_03062019_SUBMITTED.pdf
Autor:
David J. Conway, Aubrey J. Cunnington, Thomas D. Otto, Athina Georgiadou, Michael Levin, Lachlan J. M. Coin, Davis Nwakanma, Michael Walther, Lindsay B. Stewart, Hyun Jae Lee
The pathogenesis of infectious diseases depends on the interaction of host and pathogen. In Plasmodium falciparum malaria, host and parasite processes can be assessed by dual RNA-sequencing of blood from infected patients. Here we performed dual tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a136d142ab24b3e977368600838b815
http://hdl.handle.net/10044/1/61248
http://hdl.handle.net/10044/1/61248