Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Athina Dritsoula"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
The establishment of new blood vessels, and their subsequent stabilization, is a critical process that facilitates tissue growth and organ development. Once established, vessels need to diversify to meet the specific needs of the local tissue and to
Externí odkaz:
https://doaj.org/article/d74c5d8a7e6149f198fd5b880c0fddc2
Autor:
Athina Dritsoula, Laura Dowsett, Camilla Pilotti, Marie N. O’Connor, Stephen E. Moss, John Greenwood
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Leucine-rich α-2-glycoprotein 1 (LRG1) is a secreted glycoprotein that under physiological conditions is produced predominantly by the liver. In disease, its local induction promotes pathogenic neovascularisation while its inhibition leads
Externí odkaz:
https://doaj.org/article/1a2cbf8d2f2644c7a2d7e5400e597c35
Autor:
Athina Dritsoula, Maria Kislikova, Amin Oomatia, Amy P. Webster, Stephan Beck, Markella Ponticos, Ben Lindsey, Jill Norman, David C. Wheeler, Thomas Oates, Ben Caplin
Publikováno v:
Epigenetics, Vol 16, Iss 7, Pp 718-728 (2021)
Chronic kidney disease (CKD) related cardiovascular disease (CVD) is characterized by vascular remodelling with well-established structural and functional changes in the vascular wall such as arterial stiffness, matrix deposition, and calcification.
Externí odkaz:
https://doaj.org/article/f0625af892b84ce089e63ce98d6f558f
Autor:
Athina Dritsoula, Laura Dowsett, Camilla Pilotti, Marie N. O’Connor, Stephen E. Moss, John Greenwood
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/246231a7bfe54c19851fdf862fe84300
Autor:
Athina Dritsoula, Laura Dowsett, Camilla Pilotti, Marie N. O’Connor, Stephen E. Moss, John Greenwood
Publikováno v:
Scientific reports. 12(1)
Leucine-rich α-2-glycoprotein 1 (LRG1) is a secreted glycoprotein that under physiological conditions is produced predominantly by the liver. In disease, its local induction promotes pathogenic neovascularisation while its inhibition leads to reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eed422761d77ea2680747a127fee4f0
https://pubmed.ncbi.nlm.nih.gov/35351967
https://pubmed.ncbi.nlm.nih.gov/35351967
Autor:
Laura Dowsett, John Greenwood, Rene Jackstadt, Ann Ager, Marie N. O'Connor, Carlotta Camilli, Athina Dritsoula, Xiaomeng Wang, Stephen E. Moss, Angharad H. Watson, Chantelle E. Bowers, Camilla Pilotti, Julia Ohme, Jestin George, Owen J. Sansom, David Kallenberg, Markella Alatsatianos
Publikováno v:
SSRN Electronic Journal.
Vascular dysfunction contributes to the pro-oncogenic tumor microenvironment and impedes the delivery of therapeutics. Normalizing of the tumor vasculature has therefore become a potential therapeutic objective. We previously reported that the secret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1efea37a655dacbf3c8cff56c8eca6a
https://doi.org/10.2139/ssrn.3732408
https://doi.org/10.2139/ssrn.3732408
Autor:
Stephan Beck, Jill T. Norman, David C. Wheeler, Amin Oomatia, Ben Lindsey, Markella Ponticos, Thomas Oates, Amy P. Webster, Ben Caplin, Athina Dritsoula, Maria Kislikova
Publikováno v:
Epigenetics
Chronic kidney disease (CKD) related cardiovascular disease (CVD) is characterized by vascular remodelling with well-established structural and functional changes in the vascular wall such as arterial stiffness, matrix deposition, and calcification.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1bce5c1702bac440f990e18cfaaa995
Autor:
Owen J. Sansom, Markella Alatsatianos, Marie N. O'Connor, Stephen E. Moss, Rene Jackstadt, Hellmut G. Augustin, Ann Ager, Athina Dritsoula, Mahak Singhal, Chantelle E. Bowers, Julia Ohme, David Kallenberg, Xiaomeng Wang, Jack W.D. Blackburn, Carlotta Camilli, John A. Greenwood, Laura Dowsett, Jestin George, H. Angharad Watson, Camilla Pilotti
Publikováno v:
Med. 2:1231-1252.e10
Summary Background A poorly functioning tumor vasculature is pro-oncogenic and may impede the delivery of therapeutics. Normalizing the vasculature, therefore, may be beneficial. We previously reported that the secreted glycoprotein leucine-rich α-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe3d0e28938d8a658ca2ac6ca29563b
https://doi.org/10.1016/j.medj.2021.10.002
https://doi.org/10.1016/j.medj.2021.10.002
Autor:
John A. Greenwood, Camilla Pilotti, Athina Dritsoula, Stephen E. Moss, Julia Ohme, Marie N. O'Connor, Angharad H. Watson, Ann Ager, Carlotta Camilli, David Kallenberg, Markella Alatsatianos
Publikováno v:
Cancer Research. 80:391-391
Although the use of checkpoint inhibitors and adoptive T cell therapy have been reported in multiple cancers resulting in a plethora of clinical trials, the efficacy of these therapeutic strategies is often limited by the presence of impaired vascula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d43cdeac8f15a5ceefa3e6db05180f81
https://doi.org/10.1158/1538-7445.am2020-391
https://doi.org/10.1158/1538-7445.am2020-391
Autor:
Athina, Dritsoula, Ioannis, Papaioannou, Sandra G, Guerra, Carmen, Fonseca, Javier, Martin, Ariane L, Herrick, David J, Abraham, Christopher P, Denton, Markella, Ponticos
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 70(6)
NKX2-5 is a homeobox transcription factor that is required for the formation of the heart and vessels during development, with significant postnatal down-regulation and reactivation in disease states, characterized by vascular remodeling. The purpose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fbec2ffe0fba76c8d1e00896fa31e101
https://pubmed.ncbi.nlm.nih.gov/29342503
https://pubmed.ncbi.nlm.nih.gov/29342503