Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Atherosclerosis/genetics"'
Autor:
Bazioti, Venetia, La Rose, Anouk M, Maassen, Sjors, Bianchi, Frans, de Boer, Rinse, Halmos, Benedek, Dabral, Deepti, Guilbaud, Emma, Flohr-Svendsen, Arthur, Groenen, Anouk G, Marmolejo-Garza, Alejandro, Koster, Mirjam H, Kloosterhuis, Niels J, Havinga, Rick, Pranger, Alle T, Langelaar-Makkinje, Miriam, de Bruin, Alain, van de Sluis, Bart, Kohan, Alison B, Yvan-Charvet, Laurent, van den Bogaart, Geert, Westerterp, Marit, LS Pathobiologie, Dep Biomolecular Health Sciences, Pathobiologie, dPB RMSC
Publikováno v:
Nature Communications, 13(1):3799. Nature Publishing Group
Nature Communications, 13(1), 1. Nature Publishing Group
Nature Communications, 13(1), 1. Nature Publishing Group
Atherosclerosis is a chronic inflammatory disease driven by hypercholesterolemia. During aging, T cells accumulate cholesterol, potentially affecting inflammation. However, the effect of cholesterol efflux pathways mediated by ATP-binding cassette A1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c26bb22e2334922f1b405e9030d0de29
https://dspace.library.uu.nl/handle/1874/421411
https://dspace.library.uu.nl/handle/1874/421411
Autor:
George Hindy, Daniel J. Tyrrell, Alexi Vasbinder, Changli Wei, Feriel Presswalla, Hui Wang, Pennelope Blakely, Ayse Bilge Ozel, Sarah Graham, Grace H. Holton, Joseph Dowsett, Akl C. Fahed, Kingsley-Michael Amadi, Grace K. Erne, Annika Tekmulla, Anis Ismail, Christopher Launius, Nona Sotoodehnia, James S. Pankow, Lise Wegner Thørner, Christian Erikstrup, Ole Birger Pedersen, Karina Banasik, Søren Brunak, Henrik Ullum, Jesper Eugen-Olsen, Sisse Rye Ostrowski, Mary E. Haas, Jonas B. Nielsen, Luca A. Lotta, Gunnar Engström, Olle Melander, Marju Orho-Melander, Lili Zhao, Venkatesh L. Murthy, David J. Pinsky, Cristen J. Willer, Susan R. Heckbert, Jochen Reiser, Daniel R. Goldstein, Karl C. Desch, Salim S. Hayek
Publikováno v:
Hindy, G, Tyrrell, D J, Vasbinder, A, Wei, C, Presswalla, F, Wang, H, Blakely, P K, Ozel, A B, Graham, S E, Holton, G H, Dowsett, J, Fahed, A C, Amadi, K-M, Erne, G K, Tekumulla, A, Ismail, A, Launius, C, Sotoodehnia, N, Pankow, J S, Thørner, L W, Erikstrup, C, Pedersen, O B, Banasik, K, Brunak, S, Ullum, H, Eugen-Olsen, J, Ostrowski, S R, Haas, M E, Nielsen, J B, Lotta, L A, Engström, G, Melander, O, Orho-Melander, M, Zhao, L, Murthy, V L, Pinsky, D J, Willer, C J, Heckbert, S R, Reiser, J, Goldstein, D R, Desch, K C, Hayek, S S & DBDS Consortium 2022, ' Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis ', Journal of Clinical Investigation, vol. 132, no. 24, e158788 . https://doi.org/10.1172/JCI158788
People with kidney disease are disproportionately affected by atherosclerosis for unclear reasons. Soluble urokinase plasminogen activator receptor (suPAR) is an immune-derived mediator of kidney disease, levels of which are strongly associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1490877437423dd037404e38c19ab9ba
https://pubmed.ncbi.nlm.nih.gov/36194491
https://pubmed.ncbi.nlm.nih.gov/36194491
Autor:
Zhang, Xi, Wang, Zhihua, Zhang, Chuankai, Li, Yutao, Lu, Shu, Steffens, Sabine, Mohanta, Sarajo, Weber, Christian, Habenicht, Andreas, Yin, Changjun, Ramji, Dipak
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619230
Atherosclerosis Methods and Protocols, 2419, 715-726
Atherosclerosis Methods and Protocols, 2419, 715-726
A major goal of methodologies related to large scale gene expression analyses is to initiate comprehensive information on transcript signatures in single cells within the tissue's anatomy. Until now, this could be achieved in a stepwise experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d561bac28f124c84ed6b1211fc6272a4
https://doi.org/10.1007/978-1-0716-1924-7_43
https://doi.org/10.1007/978-1-0716-1924-7_43
Autor:
Zhihua Wang, Xi Zhang, Chuankai Zhang, Yutao Li, Shu Lu, Sarajo Mohanta, Christian Weber, Andreas Habenicht, Changjun Yin
Publikováno v:
Atherosclerosis Methods and Protocols, 2419, 727-746
Methods in Molecular Biology ISBN: 9781071619230
Methods in Molecular Biology ISBN: 9781071619230
Although various pro- and anti-inflammatory T cell subsets have been observed in murine and human atherosclerosis, principal issues of T cell immunity remain unanswered: Is atherosclerosis progression critically affected by aberrant T cell responses?
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736b6abce4928d41a2d035ccea752365
https://doi.org/10.1007/978-1-0716-1924-7_44
https://doi.org/10.1007/978-1-0716-1924-7_44
Autor:
Isabel Palma, Helena Ramos, Laura Ribeiro, Silvia Paredes, José Carlos Oliveira, Liliana Fonseca
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)
Scientific Reports
Scientific Reports
Low-density-lipoprotein cholesterol (LDL-c) guides lipid-lowering therapy, although other lipid parameters could better reflect cardiovascular disease (CVD) risk. Discordance between these parameters and LDL-c has not been evaluated in metabolic synd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54db979375da2514de1ba699ba1613e4
https://hdl.handle.net/10216/136244
https://hdl.handle.net/10216/136244
Autor:
Shizuya Yamashita, M. Mahmood Hussain, Daniel J. Rader, Jahangir Iqbal, Marit Westerterp, Masahiro Koseki, Jay H. Lefkowitch, Alan R. Tall, Joanne Hsieh, Ikuyo Ichi, Robin B. Chan, Liana Tascau, Matthew M. Molusky, Carrie L. Welch, Sandra Abramowicz, Shunichi Takiguchi, Emi Yakushiji, Gilbert Di Paolo
Publikováno v:
Nature
Nature, 535:7611, 303-307. Nature Publishing Group
Nature, 535:7611, 303-307. Nature Publishing Group
Cellular mechanisms that mediate steatohepatitis, an increasingly prevalent condition in the Western world for which no therapies are available, are poorly understood. Despite the fact that its synthetic agonists induce fatty liver, the liver X recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09979db7c9fd77e84dfeb0184b7bfcaf
https://doi.org/10.1038/nature18628
https://doi.org/10.1038/nature18628
Publikováno v:
Cell reports. 13(1):132-144
Enhanced glucose utilization can be visualized in atherosclerotic lesions and may reflect a high glycolytic rate in lesional macrophages, but its causative role in plaque progression remains unclear. We observe that the activity of the carbohydrate-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___00893::105e45ab1a7e67ff3f3514758c278b30
https://doi.org/10.1016/j.celrep.2015.08.068
https://doi.org/10.1016/j.celrep.2015.08.068
Autor:
Gorenjak, Vesna, Aldasoro Arguinano, Alex-Ander, Dadé, Sébastien, Stathopoulou, Maria, Vance, Dwaine, Masson, Christine, Visvikis-Siest, Sophie
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.7160. ⟨10.1038/s41598-018-25553-y⟩
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.7160. ⟨10.1038/s41598-018-25553-y⟩
International audience; Triggering receptor expressed on myeloid cells 2 (TREM2) is known for its anti-inflammatory properties during the immune response, and influences negatively on TNF-α expression levels. Genetic epidemiology studies have identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b95d0bee6105959acfb3d6cd248ff748
https://pubmed.ncbi.nlm.nih.gov/29740051
https://pubmed.ncbi.nlm.nih.gov/29740051
Autor:
Andrew J. Murphy, Marit Westerterp, Ira Tabas, Ayelet Gonen, Joseph L. Witztum, Manikandan Subramanian, Alan R. Tall, Mi Wang, Carrie L. Welch, Sandra Abramowicz
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology, 34(5), 976-984. Lippincott Williams and Wilkins
Arteriosclerosis, thrombosis, and vascular biology, 34(5), 976-984. LIPPINCOTT WILLIAMS & WILKINS
Arteriosclerosis, thrombosis, and vascular biology, 34(5), 976-984. LIPPINCOTT WILLIAMS & WILKINS
Objective— Coronary heart disease is associated with monocytosis. Studies using animal models of monocytosis and atherosclerosis such as ApoE −/− mice have shown bone marrow (BM) hematopoietic stem and multipotential progenitor cell (HSPC) expa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef2f2ebdee33cce30b41738784eef6aa
https://doi.org/10.1161/atvbaha.113.303097
https://doi.org/10.1161/atvbaha.113.303097
Autor:
Pal Pacher, Christian M. Matter, Fabienne Burger, Sabine Steffens, Aurélien Thomas, Bart Staels, Graziano Pelli, Benjamin F. Cravatt, Anne Tailleux, Andreas Zimmer, Filippo Molica, Christian Staub
Publikováno v:
Journal of lipid research
Journal of Lipid Research, Vol 54, Iss 5, Pp 1360-1368 (2013)
Journal of lipid research, vol. 54, no. 5, pp. 1360-1368
JOURNAL OF LIPID RESEARCH
Journal of Lipid Research, Vol 54, Iss 5, Pp 1360-1368 (2013)
Journal of lipid research, vol. 54, no. 5, pp. 1360-1368
JOURNAL OF LIPID RESEARCH
Percutaneous transluminal angioplasty is frequently used in patients with severe arterial narrowing due to atherosclerosis. However, it induces severe arterial injury and an inflammatory response leading to restenosis. Here, we studied a potential ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a9b5085aec78c6209b15c04be85760f