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pro vyhledávání: '"Atherosclerosis/genetics"'
Akademický článek
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Autor:
Pascal J, Goldschmidt-Clermont, David M, Seo, Liyong, Wang, Gary W, Beecham, Zhao Jun, Liu, Roberto I, Vazquez-Padron, Chunming, Dong, Joshua M, Hare, Michael S, Kapiloff, Nanette H, Bishopric, Margaret, Pericak-Vance, Jeffery M, Vance, Omaida C, Velazquez
Publikováno v:
Current opinion in molecular therapeutics. 12(6)
Atherosclerosis and its associated complications remain the primary cause of death in humans. Aging is the main contributor to atherosclerosis, compared with any other risk factor, yet the specific manner in which age increases risk (the 'aging-risk'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::05bdb9c2124d6a48f5cc51554b39f787
https://pubmed.ncbi.nlm.nih.gov/21154163
https://pubmed.ncbi.nlm.nih.gov/21154163
Autor:
Bazioti, Venetia, La Rose, Anouk M, Maassen, Sjors, Bianchi, Frans, de Boer, Rinse, Halmos, Benedek, Dabral, Deepti, Guilbaud, Emma, Flohr-Svendsen, Arthur, Groenen, Anouk G, Marmolejo-Garza, Alejandro, Koster, Mirjam H, Kloosterhuis, Niels J, Havinga, Rick, Pranger, Alle T, Langelaar-Makkinje, Miriam, de Bruin, Alain, van de Sluis, Bart, Kohan, Alison B, Yvan-Charvet, Laurent, van den Bogaart, Geert, Westerterp, Marit, LS Pathobiologie, Dep Biomolecular Health Sciences, Pathobiologie, dPB RMSC
Publikováno v:
Nature Communications, 13(1):3799. Nature Publishing Group
Nature Communications, 13(1), 1. Nature Publishing Group
Nature Communications, 13(1), 1. Nature Publishing Group
Atherosclerosis is a chronic inflammatory disease driven by hypercholesterolemia. During aging, T cells accumulate cholesterol, potentially affecting inflammation. However, the effect of cholesterol efflux pathways mediated by ATP-binding cassette A1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c26bb22e2334922f1b405e9030d0de29
https://dspace.library.uu.nl/handle/1874/421411
https://dspace.library.uu.nl/handle/1874/421411
Publikováno v:
In Atherosclerosis (Supplements) (Component) 2002 3(2):147-148
Autor:
George Hindy, Daniel J. Tyrrell, Alexi Vasbinder, Changli Wei, Feriel Presswalla, Hui Wang, Pennelope Blakely, Ayse Bilge Ozel, Sarah Graham, Grace H. Holton, Joseph Dowsett, Akl C. Fahed, Kingsley-Michael Amadi, Grace K. Erne, Annika Tekmulla, Anis Ismail, Christopher Launius, Nona Sotoodehnia, James S. Pankow, Lise Wegner Thørner, Christian Erikstrup, Ole Birger Pedersen, Karina Banasik, Søren Brunak, Henrik Ullum, Jesper Eugen-Olsen, Sisse Rye Ostrowski, Mary E. Haas, Jonas B. Nielsen, Luca A. Lotta, Gunnar Engström, Olle Melander, Marju Orho-Melander, Lili Zhao, Venkatesh L. Murthy, David J. Pinsky, Cristen J. Willer, Susan R. Heckbert, Jochen Reiser, Daniel R. Goldstein, Karl C. Desch, Salim S. Hayek
Publikováno v:
Hindy, G, Tyrrell, D J, Vasbinder, A, Wei, C, Presswalla, F, Wang, H, Blakely, P K, Ozel, A B, Graham, S E, Holton, G H, Dowsett, J, Fahed, A C, Amadi, K-M, Erne, G K, Tekumulla, A, Ismail, A, Launius, C, Sotoodehnia, N, Pankow, J S, Thørner, L W, Erikstrup, C, Pedersen, O B, Banasik, K, Brunak, S, Ullum, H, Eugen-Olsen, J, Ostrowski, S R, Haas, M E, Nielsen, J B, Lotta, L A, Engström, G, Melander, O, Orho-Melander, M, Zhao, L, Murthy, V L, Pinsky, D J, Willer, C J, Heckbert, S R, Reiser, J, Goldstein, D R, Desch, K C, Hayek, S S & DBDS Consortium 2022, ' Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis ', Journal of Clinical Investigation, vol. 132, no. 24, e158788 . https://doi.org/10.1172/JCI158788
People with kidney disease are disproportionately affected by atherosclerosis for unclear reasons. Soluble urokinase plasminogen activator receptor (suPAR) is an immune-derived mediator of kidney disease, levels of which are strongly associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1490877437423dd037404e38c19ab9ba
https://pubmed.ncbi.nlm.nih.gov/36194491
https://pubmed.ncbi.nlm.nih.gov/36194491
Autor:
Zhang, Xi, Wang, Zhihua, Zhang, Chuankai, Li, Yutao, Lu, Shu, Steffens, Sabine, Mohanta, Sarajo, Weber, Christian, Habenicht, Andreas, Yin, Changjun, Ramji, Dipak
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619230
Atherosclerosis Methods and Protocols, 2419, 715-726
Atherosclerosis Methods and Protocols, 2419, 715-726
A major goal of methodologies related to large scale gene expression analyses is to initiate comprehensive information on transcript signatures in single cells within the tissue's anatomy. Until now, this could be achieved in a stepwise experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d561bac28f124c84ed6b1211fc6272a4
https://doi.org/10.1007/978-1-0716-1924-7_43
https://doi.org/10.1007/978-1-0716-1924-7_43
Autor:
Zhihua Wang, Xi Zhang, Chuankai Zhang, Yutao Li, Shu Lu, Sarajo Mohanta, Christian Weber, Andreas Habenicht, Changjun Yin
Publikováno v:
Atherosclerosis Methods and Protocols, 2419, 727-746
Methods in Molecular Biology ISBN: 9781071619230
Methods in Molecular Biology ISBN: 9781071619230
Although various pro- and anti-inflammatory T cell subsets have been observed in murine and human atherosclerosis, principal issues of T cell immunity remain unanswered: Is atherosclerosis progression critically affected by aberrant T cell responses?
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736b6abce4928d41a2d035ccea752365
https://doi.org/10.1007/978-1-0716-1924-7_44
https://doi.org/10.1007/978-1-0716-1924-7_44