Výsledky vyhledávání - "Athena M, Cherry"

Lymphoid blast transformation in an MPN with BCR-JAK2 treated with ruxolitinib: putative mechanisms of resistance

Autor: Stephen B. Montgomery, Mark D. Ewalt, Beth A. Pitel, Hutton M. Kearney, Laure Fresard, Robert S. Ohgami, Jason D. Merker, Athena M. Cherry, Yanli Hou, Jason Gotlib, Daniel A. Arber, Charles D. Bangs, Linda B. Baughn, Justin A. Chen, Krishna M. Roskin, Andrew Fire, Kathryn E. Pearce

Publikováno v: Blood Adv

The basis for acquired resistance to JAK inhibition in patients with JAK2-driven hematologic malignancies is not well understood. We report a patient with a myeloproliferative neoplasm (MPN) with a BCR activator of RhoGEF and GTPase (BCR)–JAK2 fusi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276660058f4413e824d824206a84497f
https://doi.org/10.1182/bloodadvances.2020004174

Zobrazit plný text záznamu

Genetic Subtypes of Systemic Anaplastic Large Cell Lymphoma Show Distinct Differences in PD-L1 Expression and Regulatory and Cytotoxic T Cells in the Tumor Microenvironment

Autor: Juliana Pereira, Vidhya Manohar, Dita Gratzinger, Luis Alberto de Padua Covas Lage, Charles D. Bangs, Raymundo Soares Azevedo, Cristiane R. Ferreira, Shuchun Zhao, Yasodha Natkunam, Athena M. Cherry, Maria Claudia Nogueira Zerbini

Publikováno v: Applied Immunohistochemistry & Molecular Morphology. 28:10-16

Anaplastic large cell lymphomas (ALCL) encompass several subgroups that differ in their clinical presentation, genetic features, and prognosis. We characterized the genetic subgroups of 74 patients with ALCL and correlated programmed death ligand 1 (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac3551ce141fbf96473170aa0f6597e
https://doi.org/10.1097/pai.0000000000000798

Zobrazit plný text záznamu

Technical standards for the interpretation and reporting of constitutional copy number variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics (ACMG) and the Clinical Genome Resource (ClinGen)

Autor: Athena M. Cherry, Hutton M. Kearney, Swaroop Aradhya, Erica F. Andersen, Gordana Raca, Sibel Kantarci, Erik C. Thorland, Deborah I. Ritter, Sarah T. South, Erin Rooney Riggs, Ankita Patel, Christa Lese Martin, Daniel E. Pineda-Alvarez

Publikováno v: Genetics in medicine : official journal of the American College of Medical Genetics

Copy-number analysis to detect disease-causing losses and gains across the genome is recommended for the evaluation of individuals with neurodevelopmental disorders and/or multiple congenital anomalies, as well as for fetuses with ultrasound abnormal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388f33a8f8bdbeecfa12b659e8e76c82
http://europepmc.org/articles/PMC7313390

Zobrazit plný text záznamu

Perinatal distress in 1p36 deletion syndrome can mimic hypoxic ischemic encephalopathy

Publikováno v: Am J Med Genet A
American journal of medical genetics. Part A, vol 179, iss 8

1p36 deletion syndrome is a well-described condition with a recognizable phenotype, including cognitive impairment, seizures, and structural brain anomalies such as periventricular leukomalacia (PVL). In a large series of these individuals by Battagl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::666822da8ce421ba9792ab05c0ea6ac9
https://doi.org/10.1002/ajmg.a.61266

Zobrazit plný text záznamu

Akademický článek

Complex or monosomal karyotype and not blast percentage is associated with poor survival in acute myeloid leukemia and myelodysplastic syndrome patients with inv(3)(q21q26.2)/t(3;3)(q21;q26.2): a Bone Marrow Pathology Group study

Publikováno v: Haematologica, Vol 99, Iss 5 (2014)

Acute myeloid leukemia and myelodysplastic syndrome with inv(3)(q21q26.2)/t(3;3)(q21;q26.2) have a poor prognosis. Indeed, the inv(3)(q21q26.2)/t(3;3)(q21;q26.2) has been recognized as a poor risk karyotype in the revised International Prognostic Sco

Externí odkaz: https://doaj.org/article/d9f87de7034c45ec8554cbe976bf06a7

Zobrazit plný text záznamu

Akademický článek

Comprehensive whole-genome sequencing of an early-stage primary myelofibrosis patient defines low mutational burden and non-recurrent candidate genes

Publikováno v: Haematologica, Vol 98, Iss 11 (2013)

In order to identify novel somatic mutations associated with classic BCR/ABL1-negative myeloproliferative neoplasms, we performed high-coverage genome sequencing of DNA from peripheral blood granulocytes and cultured skin fibroblasts from a patient w

Externí odkaz: https://doaj.org/article/115e569bec7d49db8c8c73908b664b8b

Zobrazit plný text záznamu

Joint single cell DNA-seq and RNA-seq of gastric cancer cell lines reveals rules of in vitro evolution

Autor: Noemi Andor, Jiamin Chen, Cristina Blaj, Athena M. Cherry, Billy T. Lau, Charles D. Bangs, Carlos Suárez, Matthew Kubit, Susan M. Grimes, Hanlee P. Ji, Claudia Catalanotti, Anuja Sathe

Publikováno v: Nar Genomics and Bioinformatics

Cancer cell lines are not homogeneous nor are they static in their genetic state and biological properties. Genetic, transcriptional and phenotypic diversity within cell lines contributes to the lack of experimental reproducibility frequently observe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31253337975391ad1213d13b1317d59f
https://doi.org/10.1093/nargab/lqaa016

Zobrazit plný text záznamu

Immune checkpoint blockade as a potential therapeutic strategy for undifferentiated malignancies

Autor: Shuchun Zhao, Kelly A. Devereaux, Matt van de Rijn, Vivek Charu, Charles D. Bangs, Yasodha Natkunam, Athena M. Cherry, Gregory W. Charville

Publikováno v: Human Pathology. 82:39-45

Undifferentiated malignancies (UMs) encompass a diverse set of aggressive tumors that pose not only a diagnostic challenge but also a challenge for clinical management. Most tumors in this category are currently treated empirically with nonspecific c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2224d4f590da0317c0534d167eb12094
https://doi.org/10.1016/j.humpath.2018.06.034

Zobrazit plný text záznamu

Investigating human placentation and pregnancy using first trimester chorionic villi

Autor: Eduardo Gonzalez-Maldonado, Mary E. Norton, Jingwei Yu, Julie C. Baker, Athena M. Cherry, Shilpa Chetty, Zhongxia Qi, Roberta L. Hannibal, Joanne Lau, Margarida Cardoso-Moreira

Publikováno v: Placenta. 65:65-75

Chorionic villus sampling (CVS), routinely used for prenatal diagnosis of cytogenetic disorders, also possesses great potential for the study of placentation. To better understand villus biology, human placentation, and how these relate to pregnancy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::059b60813fa786d87cc30ee2ac7e51d0
https://doi.org/10.1016/j.placenta.2018.03.005

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání