Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Athena F, Zuppa"'
Autor:
Todd A. Miano, PharmD, PhD, Athena F. Zuppa, MD, MSCE, Rui Feng, PhD, Stephen Griffiths, BS, Laurel Kalman, BA, Michelle Oyster, MS, Edward Cantu, MD, MSCE, Wei Yang, PhD, Joshua M. Diamond, MD, MSCE, Jason D. Christie, MD, MSCE, Marc H. Scheetz, PharmD, MSC, Michael G.S. Shashaty, MD, MSCE
Publikováno v:
JHLT Open, Vol 6, Iss , Pp 100134- (2024)
Background: Tacrolimus therapy is standard of care for immunosuppression after lung transplantation. However, tacrolimus exposure variability during the early postoperative period may contribute to poor outcomes in this population. Few studies have e
Externí odkaz:
https://doaj.org/article/d342a6ab97e04758aad16f96d6b2db4f
Autor:
Zhenziang Fan, Kate F. Kernan, Yidi Qin, Scott Canna, Robert A. Berg, David Wessel, Murray M. Pollack, Kathleen Meert, Mark Hall, Christopher Newth, John C. Lin, Allan Doctor, Tom Shanley, Tim Cornell, Rick E. Harrison, Athena F. Zuppa, Katherine Sward, J. Michael Dean, H. J. Park, Joseph A. Carcillo
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-12 (2023)
Abstract Background One of five global deaths are attributable to sepsis. Hyperferritinemic sepsis (> 500 ng/mL) is associated with increased mortality in single-center studies. Our pediatric research network’s objective was to obtain rationale for
Externí odkaz:
https://doaj.org/article/dc1f2d5909cd4b9fa2e610b7b3a2910d
Autor:
Yidi Qin, Kate F. Kernan, Zhenjiang Fan, Hyun-Jung Park, Soyeon Kim, Scott W. Canna, John A. Kellum, Robert A. Berg, David Wessel, Murray M. Pollack, Kathleen Meert, Mark Hall, Christopher Newth, John C. Lin, Allan Doctor, Tom Shanley, Tim Cornell, Rick E. Harrison, Athena F. Zuppa, Russell Banks, Ron W. Reeder, Richard Holubkov, Daniel A. Notterman, J. Michael Dean, Joseph A. Carcillo
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-16 (2022)
Abstract Background Thrombotic microangiopathy-induced thrombocytopenia-associated multiple organ failure and hyperinflammatory macrophage activation syndrome are important causes of late pediatric sepsis mortality that are often missed or have delay
Externí odkaz:
https://doaj.org/article/97816617627644b9825463ea1be360f3
Autor:
Céline Thibault, Athena F. Zuppa
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
BackgroundDexmedetomidine is a sedative and analgesic increasingly used in children supported with extracorporeal membrane oxygenation (ECMO). No data is available to describe the pharmacokinetics (PK) of dexmedetomidine in this population.MethodsWe
Externí odkaz:
https://doaj.org/article/04334cfad4f84e3f9037aa0da5bad1bb
Autor:
Gideon Stitt, Samuel Dubinsky, Andrea Edginton, Yuan-Shung V. Huang, Athena F. Zuppa, Kevin Watt, Kevin Downes
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
ObjectivesContinuous renal replacement therapy (CRRT) is commonly employed in critically ill children and is known to affect antimicrobial pharmacokinetics. There is a lack of readily available, evidence-based antimicrobial dosing recommendations in
Externí odkaz:
https://doaj.org/article/65b6253162fb49c7887170c8ad52ebfa
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1336 (2023)
Area under the curve (AUC)-directed vancomycin therapy is recommended, but Bayesian AUC estimation in critically ill children is difficult due to inadequate methods for estimating kidney function. We prospectively enrolled 50 critically ill children
Externí odkaz:
https://doaj.org/article/cfc882c7d41a461ba148ef5ff7f16fd5
Autor:
Alexandra Tsitsiklis, PhD, Christina M Osborne, MD, Jack Kamm, PhD, Kayla Williamson, MS, Katrina Kalantar, PhD, Gytis Dudas, PhD, Saharai Caldera, BA, Amy Lyden, BA, Michelle Tan, BS, Norma Neff, PhD, Victoria Soesanto, BS, J Kirk Harris, PhD, Lilliam Ambroggio, PhD, Aline B Maddux, MD, Todd C Carpenter, MD, Ron W Reeder, PhD, Chris Locandro, MS, Eric A F Simões, ProfMD, Matthew K Leroue, MD, Mark W Hall, ProfMD, Athena F Zuppa, ProfMD, Joseph Carcillo, ProfMD, Kathleen L Meert, ProfMD, Anil Sapru, ProfMD, Murray M Pollack, ProfMD, Patrick S McQuillen, ProfMD, Daniel A Notterman, ProfMD, J Michael Dean, ProfMD, Matt S Zinter, MD, Brandie D Wagner, PhD, Joseph L DeRisi, ProfPhD, Peter M Mourani, ProfMD, Charles R Langelier, MDPhD
Publikováno v:
The Lancet Microbe, Vol 3, Iss 4, Pp e284-e293 (2022)
Summary: Background: Lower respiratory tract infections (LRTI) are a leading cause of critical illness and mortality in mechanically ventilated children; however, the pathogenic microbes frequently remain unknown. We combined traditional diagnostics
Externí odkaz:
https://doaj.org/article/bf9afb105f554ba7841ff015408ec805
Autor:
Mallory A. Perry, PhD, RN, Onella S. Dawkins-Henry, MS, Ronke E. Awojoodu, RN, MPH, Jennifer Blumenthal, MSN, Lisa A. Asaro, MS, David Wypij, PhD, Sapna R. Kudchadkar, MD, PhD, Athena F. Zuppa, MD, MSCE, Martha A.Q. Curley, PhD, RN
Publikováno v:
Contemporary Clinical Trials Communications, Vol 23, Iss , Pp 100840- (2021)
Often, pediatric intensive care environments are not conducive to healing the sick. Critically ill children experience disruptions in their circadian rhythms, which can contribute to delayed recovery and poor outcomes. We aim to test the hypothesis t
Externí odkaz:
https://doaj.org/article/dfdda377b7a34c1682ef4d128165642f
Autor:
Neethi P. Pinto, Robert A. Berg, Athena F. Zuppa, Christopher J. Newth, Murray M. Pollack, Kathleen L. Meert, Mark W. Hall, Michael Quasney, Anil Sapru, Joseph A. Carcillo, Patrick S. McQuillen, Peter M. Mourani, Ranjit S. Chima, Richard Holubkov, Vinay M. Nadkarni, Ron W. Reeder, Jerry J. Zimmerman, the Life After Pediatric Sepsis Evaluation (LAPSE) Investigators
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Background: Although some pediatric sepsis survivors experience worsening health-related quality of life (HRQL), many return to their pre-illness HRQL. Whether children can improve beyond baseline is not known. We examined a cohort of pediatric sepsi
Externí odkaz:
https://doaj.org/article/dff56ddf4f7448f48f5a395f34c7963e
Autor:
Christopher M, Horvat, Anthony, Fabio, Daniel S, Nagin, Russell K, Banks, Yidi, Qin, Hyun-Jung, Park, Kate F, Kernan, Scott W, Canna, Robert A, Berg, David, Wessel, Murray M, Pollack, Kathleen, Meert, Mark, Hall, Christopher, Newth, John C, Lin, Allan, Doctor, Tom, Shanley, Tim, Cornell, Rick E, Harrison, Athena F, Zuppa, Ron W, Reeder, Kathy, Sward, Richard, Holubkov, Daniel A, Notterman, J Michael, Dean, Joseph A, Carcillo
Publikováno v:
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 23(12)
Interest in using bedside C-reactive protein (CRP) and ferritin levels to identify patients with hyperinflammatory sepsis who might benefit from anti-inflammatory therapies has piqued with the COVID-19 pandemic experience. Our first objective was to