Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Athe M. N. Tsibris"'
Autor:
Amy Kantor, Charles Flexner, Christina Gavegnano, Michael M. Lederman, Selwyn J. Hurwitz, Sijia Tao, Edgar T. Overton, Vincent C. Marconi, Raymond F. Schinazi, Randall Tressler, James J. Kohler, Carlos del Rio, Carlee Moser, Athe M. N. Tsibris, Yong Jiang, Jeffrey L. Lennox
Publikováno v:
J Clin Pharmacol
Ruxolitinib is an FDA-approved orally administered Janus kinase (JAK 1/2) inhibitor that reduces cytokine-induced inflammation. As part of a randomized, Phase 2, open label trial, ruxolitinib (10 mg, bid) was administered to HIV(+), virologically sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a59d2322e8b0db4dc34843b17cb885
https://doi.org/10.1002/jcph.1930
https://doi.org/10.1002/jcph.1930
Autor:
Anjali Devi Sivakumar, Fenil Doshi, Athe M. N. Tsibris, Deeksha Kartik, John C. Petrozza, Hadi Shafiee, Manoj Kumar Kanakasabapathy, John A. Branda, Charles L. Bormann, Rohan Pooniwala, Raghav Gupta, Prudhvi Thirumalaraju, Hemanth Kandula, Daniel R. Kuritzkes
Publikováno v:
Nat Biomed Eng
In machine learning for image-based medical diagnostics, supervised convolutional neural networks are typically trained with large and expertly annotated datasets obtained using high-resolution imaging systems. Moreover, the network’s performance c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50824745ccc3e9166cbc3d127e586ac5
https://doi.org/10.1038/s41551-021-00733-w
https://doi.org/10.1038/s41551-021-00733-w
Autor:
Alejandro B. Balazs, Josalyn L. Cho, Björn Corleis, Abigail E. Schiff, Thomas J. Diefenbach, Stephanie Banning, Douglas S. Kwon, Amy K. Dickey, Alice H. Linder, Martin J. Deymier, Robert J. Wilkinson, Athe M. N. Tsibris, Shillah N Luhembo, Gerhard Walzl, Wendy A. Burgers, Benjamin D. Medoff
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Alveolar macrophages (AMs) are critical for defense against airborne pathogens and AM dysfunction is thought to contribute to the increased burden of pulmonary infections observed in individuals living with HIV-1 (HIV). While HIV nucleic acids have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3365e420b5ac3ac5371f38908be01ab6
https://doaj.org/article/0c180a3a227b47598d0db0a78f5b3e8a
https://doaj.org/article/0c180a3a227b47598d0db0a78f5b3e8a
Autor:
Daniel R. Kuritzkes, Katrina Armstrong, Michael Dougan, Colline Wong, Rebecca M. Baron, Kathryn T. Hall, Edward T. Ryan, Alicja Piechocka-Trocha, Kendyll Coxen, Dusan Hanidziar, Caroline Atyeo, Stephanie Fischinger, Jonathan Z. Li, Athe M. N. Tsibris, Bruce D. Walker, Xu G. Yu, Andrew T. Chan, Lindsey R. Baden, Nikolaus Jilg, Yijia Li, Elizabeth Gillespie, Daniel P Worrall, Galit Alter, Francoise Giguel, Rida Chishti, Keith T. Flaherty, Heather Corry, James Regan, Alexandra Rosenthal, Jesse Fajnzylber
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications
Nature Communications
The relationship between SARS-CoV-2 viral load and risk of disease progression remains largely undefined in coronavirus disease 2019 (COVID-19). Here, we quantify SARS-CoV-2 viral load from participants with a diverse range of COVID-19 disease severi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d62a88034260713cbcbf660080bdc9
https://doaj.org/article/d3b04d9a629f44488b9f26c98ed75ef0
https://doaj.org/article/d3b04d9a629f44488b9f26c98ed75ef0
Autor:
Ronald Swanstrom, Trinity Zang, Daniel R. Kuritzkes, Athe M. N. Tsibris, Phillip J. Tomezsko, Anthony T. Papenfuss, Ann Emery, Matthew D. Edwards, Tammy C. T. Lan, Paromita Gupta, Harish Swaminathan, Paul D. Bieniasz, Sitara Persad, Lachlan McIntosh, Vincent Corbin, Silvi Rouskin, Margalit Glasgow
Publikováno v:
Nature
Human immunodeficiency virus 1 (HIV-1) is a retrovirus with a ten-kilobase single-stranded RNA genome. HIV-1 must express all of its gene products from a single primary transcript, which undergoes alternative splicing to produce diverse protein produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada02574b201f96085c349314b09362f
http://europepmc.org/articles/PMC7310298
http://europepmc.org/articles/PMC7310298
Autor:
Daniel R. Kuritzkes, Fernanda Ferreira, Olivia Wilkins, Qianjing He, Olivia Roberts‐Sano, Athe M. N. Tsibris, Stephanie Banning
Publikováno v:
Journal of the International AIDS Society
Introduction HIV rebounds after cessation of antiretroviral therapy, representing a barrier to cure. To better understand the virus reservoir, analysis pipelines have been developed that categorize proviral sequences as intact or defective, and furth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99df58b671a7e4ac5aedaf517e3d6398
http://europepmc.org/articles/PMC8264403
http://europepmc.org/articles/PMC8264403
Autor:
Athe M. N. Tsibris, Suhui Zhao
Publikováno v:
Viruses
Viruses, Vol 13, Iss 1197, p 1197 (2021)
Viruses, Vol 13, Iss 1197, p 1197 (2021)
While suppressive antiretroviral therapy can effectively limit HIV-1 replication and evolution, it leaves behind a residual pool of integrated viral genomes that persist in a state of reversible nonproductive infection, referred to as the HIV-1 reser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791bc35035e943fd07a3c7aca32cc8c9
https://pubmed.ncbi.nlm.nih.gov/34206546
https://pubmed.ncbi.nlm.nih.gov/34206546
Autor:
Daniel R. Kuritzkes, Mohamed Shehata Draz, Shantanu Kallakuri, Athe M. N. Tsibris, Manoj Kumar Kanakasabapathy, Dheerendranath Battalapalli, Hadi Shafiee, Anish Vasan, Aparna Sreeram, Kamyar Mehrabi Kochehbyoki
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature Communications
HIV-1 infection is a major health threat in both developed and developing countries. The integration of mobile health approaches and bioengineered catalytic motors can allow the development of sensitive and portable technologies for HIV-1 management.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d13c6b90ab1833742ac984b598256da1
http://link.springer.com/article/10.1038/s41467-018-06727-8
http://link.springer.com/article/10.1038/s41467-018-06727-8
Autor:
Athe M N Tsibris, Urboshi Pal, Allison L Schure, Ronald S Veazey, Kevin J Kunstman, Timothy J Henrich, P J Klasse, Steven M Wolinsky, Daniel R Kuritzkes, John P Moore
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28047 (2011)
Maraviroc (MVC) gels are effective at protecting rhesus macaques from vaginal SHIV transmission, but breakthrough infections can occur. To determine the effects of a vaginal MVC gel on infecting SHIV populations in a macaque model, we analyzed plasma
Externí odkaz:
https://doaj.org/article/5283bc49244e401bb6b379778e02330c
Autor:
Athe M N Tsibris, Bette Korber, Ramy Arnaout, Carsten Russ, Chien-Chi Lo, Thomas Leitner, Brian Gaschen, James Theiler, Roger Paredes, Zhaohui Su, Michael D Hughes, Roy M Gulick, Wayne Greaves, Eoin Coakley, Charles Flexner, Chad Nusbaum, Daniel R Kuritzkes
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5683 (2009)
High-throughput sequencing platforms provide an approach for detecting rare HIV-1 variants and documenting more fully quasispecies diversity. We applied this technology to the V3 loop-coding region of env in samples collected from 4 chronically HIV-i
Externí odkaz:
https://doaj.org/article/ed3bc53f5c7e4bbfbabd8a82f5be0776