Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Athanassia, Sotiropoulos"'
Autor:
Chiara Noviello, Kassandra Kobon, Voahangy Randrianarison-Huetz, Pascal Maire, France Pietri-Rouxel, Sestina Falcone, Athanassia Sotiropoulos
Publikováno v:
Cells, Vol 12, Iss 23, p 2673 (2023)
Satellite cells (SCs) are adult muscle stem cells that are mobilized when muscle homeostasis is perturbed. Here we show that RhoA in SCs is indispensable to have correct muscle regeneration and hypertrophy. In particular, the absence of RhoA in SCs p
Externí odkaz:
https://doaj.org/article/24f1aae4168b41dc9a8637da742ef716
Autor:
Matthieu Dos Santos, Stéphanie Backer, Frédéric Auradé, Matthew Man-Kin Wong, Maud Wurmser, Rémi Pierre, Francina Langa, Marcio Do Cruzeiro, Alain Schmitt, Jean-Paul Concordet, Athanassia Sotiropoulos, F. Jeffrey Dilworth, Daan Noordermeer, Frédéric Relaix, Iori Sakakibara, Pascal Maire
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The contractile properties of adult myofibers are shaped by their Myosin heavy chain isoform content. Here the authors show that a super enhancer controls the spatiotemporal expression of the genes at the fast myosin heavy chain locus by DNA looping
Externí odkaz:
https://doaj.org/article/1e1732b409944febbd7c8c1cfe87a24b
Single-nucleus RNA-seq and FISH identify coordinated transcriptional activity in mammalian myofibers
Autor:
Matthieu Dos Santos, Stéphanie Backer, Benjamin Saintpierre, Brigitte Izac, Muriel Andrieu, Franck Letourneur, Frederic Relaix, Athanassia Sotiropoulos, Pascal Maire
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Whether skeletal muscle fibre gene expression is coordinated as a whole in different nuclei in the fibre is unclear. Here, the authors use single nucleus RNAseq and ATACseq to show the transcriptome heterogeneity of muscle nuclei in the adult mouse f
Externí odkaz:
https://doaj.org/article/8503a3a7129146fea7a01f6be4dfc5d6
Autor:
Chiara Noviello, Kassandra Kobon, Léa Delivry, Thomas Guilbert, Florian Britto, Francis Julienne, Pascal Maire, Voahangy Randrianarison-Huetz, Athanassia Sotiropoulos
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103616- (2022)
Summary: Adult skeletal muscle is a plastic tissue that can adapt its size to workload. Here, we show that RhoA within myofibers is needed for overload-induced hypertrophy by controlling satellite cell (SC) fusion to the growing myofibers without aff
Externí odkaz:
https://doaj.org/article/170f75947eb64da5bf26e0da42c8da17
Autor:
Haidar Djemai, Medhi Hassani, Nissrine Daou, Zhenlin Li, Athanassia Sotiropoulos, Philippe Noirez, Dario Coletti
Publikováno v:
European Journal of Translational Myology, Vol 29, Iss 2 (2019)
Physical exercise has important effects as secondary prevention or intervention against several diseases. Endurance exercise induces local and global effects, resulting in skeletal muscle adaptations to aerobic activity and contributes to an ameliora
Externí odkaz:
https://doaj.org/article/65f5f36409564a0cbc5a52ad7b0b7e59
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0214385 (2019)
Serum response factor and its cofactor myocardin-related transcription factor (MRTF) are key elements of muscle-mass adaptation to workload. The transcription of target genes is activated when MRTF is present in the nucleus. The localization of MRTF
Externí odkaz:
https://doaj.org/article/0570f3698b9544fdae9141f3d2677882
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Externí odkaz:
https://doaj.org/article/557b56c8b5da43a18372d1233deb8323
Autor:
Wong M, Frédéric Relaix, Alain Schmitt, Francina Langa, Stéphanie Backer, Frédéric Auradé, Sakakibara I, Santos, Daan Noordermeer, Cruzeiro, Jeffrey Dilworth, Athanassia Sotiropoulos, Pierre R, Maud Wurmser, Pascal Maire, Jean-Paul Concordet
SummaryThe contractile properties of adult myofibers are shaped by their Myosin heavy chain (MYH) isoform content. We identify by snATAC-seq a 42kb super-enhancer (SE) at the locus regrouping the fast Myh (fMyh) genes. By 4C-seq we show that active f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7895d1d8759645144269e20906a8f54c
https://hal.archives-ouvertes.fr/hal-03420521/document
https://hal.archives-ouvertes.fr/hal-03420521/document
Autor:
Jonathan B Weitzman, Martine Perichon, Souhila Medjkane, Athanassia Sotiropoulos, Arnaud Divol, Ella Fung, Roberta Codato, Anne Bigot
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-53577-5⟩
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-53577-5⟩
The coordinated expression of myogenic regulatory factors, including MyoD and myogenin, orchestrates the steps of skeletal muscle development, from myoblast proliferation and cell-cycle exit, to myoblast fusion and myotubes maturation. Yet, it remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4858b582c8f1f635291cdaf9a3fb151f
http://link.springer.com/article/10.1038/s41598-019-53577-5
http://link.springer.com/article/10.1038/s41598-019-53577-5
Autor:
Léa Delivry, Francis Julienne, Athanassia Sotiropoulos, Thomas Guilbert, Pascal Maire, Voahangy Randrianarison-Huetz, Chiara Noviello, Kassandra Kobon
SummaryAdult skeletal muscle is a plastic tissue that can adapt its size to workload. Here, we show that RhoA within myofibers is needed for overload-induced hypertrophy by controlling satellite cell fusion to the growing myofibers without affecting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28f544430d4177c9ac427ac2795a298a
https://doi.org/10.1101/2021.01.18.426685
https://doi.org/10.1101/2021.01.18.426685