Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Athanasios C, Tsiatis"'
Autor:
Gilles Vassal, John M. Maris, Fred Zheng, Elizabeth Fox, Athanasios C. Tsiatis, Joe McDonough, Donna Ludwinski, Julia Glade Bender, Vickie Buenger, Pratiti Bandopadhayay, Steven G. DuBois, Katarina Luptakova, Francis J. Giles, Patrick A. Brown, Mark W. Kieran, Andrew D.J. Pearson, Christopher A. French, Rajeev Vibhakar, Kelly Bennett, Kimberly Stegmaier, Joanna S. Yi, Franck Bourdeaut, Jessica Clymer, Maureen Hattersley, Susan L. Weiner, Zariana Nikolova, Malcolm A. Smith, Louis Chesler, Eva Germovsek
Publikováno v:
European Journal of Cancer. 146:115-124
Based on biology and pre-clinical data, bromodomain and extra-terminal (BET) inhibitors have at least three potential roles in paediatric malignancies: NUT (nuclear protein in testis) carcinomas, MYC/MYCN-driven cancers and fusion-driven malignancies
Autor:
Guillermo Garcia-Manero, Amanda Przespolewski, Yasmin Abaza, Michael Byrne, Abraham P. Fong, Feng Jin, Alison J. Forgie, Athanasios C. Tsiatis, Shanhong Guan, Harry P. Erba
Publikováno v:
Blood. 140:9046-9047
Autor:
Athanasios C. Tsiatis, Andrea Pingitore, Michael Crager, Michael D. Fabrizio, Michael A. Liss, Andrew A. Wagner, Maria S. Tretiakova, Hilary Boyer, Ian M. Thompson, Jesse K. McKenney, Todd M. Morgan, Yingye Zheng, Ruixiao Lu, Peter S. Nelson, Daniel W. Lin, Martin E. Gleave, James D. Brooks, Marshall D. Brown, Lisa F. Newcomb, Suzanne Kolb, Atreya Dash
Publikováno v:
J Clin Oncol
PURPOSE The 17-gene Onco type DX Genomic Prostate Score (GPS) test predicts adverse pathology (AP) in patients with low-risk prostate cancer treated with immediate surgery. We evaluated the GPS test as a predictor of outcomes in a multicenter active
Autor:
Phillip G. Febbo, Dejan Knezevic, Anne Dee, Eric A. Klein, Cristina Magi-Galluzzi, Athanasios C. Tsiatis, Tara Maddala, Jeffrey Lawrence, Sudhir Isharwal, Sara M. Falzarano
Publikováno v:
Urology. 121:132-138
To compare the ability of loss of phosphatase and tensin homolog (PTEN) and Genomic prostate score assay (GPS) in predicting the biochemical-recurrence (BCR) and clinical-recurrence (CR) after radical prostatectomy (RP) for clinically localized prost
Autor:
Ben Powell, Amy E. DeZern, Naveen Pemmaraju, Chelsea L. Hope, Ching Hsu, Jennifer N. Saultz, Madan G. Kundu, Gail J. Roboz, Melhem Solh, Athanasios C. Tsiatis, Jason Halladay, Jackie M. Walling, Paul Watkins, Bernice Matusow, Alice S. Mims, Uma Borate, Shireen Vali, Chao Zhang, Gautam Borthakur
Publikováno v:
Blood. 138:3420-3420
Background: Relapsed and refractory myeloid malignancies including myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) remain a clinical challenge due to high mortality, morbidity, and lack of effective therapeutic agents. PLX2853 is an o
Autor:
Joseph C. Presti, Charles P. Quesenberry, Ruixiao Lu, Phillip G. Febbo, Jeong S. Han, Nan Zhang, Amethyst Leimpeter, Jun Shan, Stephen K. Van Den Eeden, Athanasios C. Tsiatis, H. Jeffrey Lawrence
Publikováno v:
European Urology. 73:129-138
A 17-gene biopsy-based reverse transcription polymerase chain reaction assay, which provides a Genomic Prostate Score (GPS-scale 0-100), has been validated as an independent predictor of adverse pathology and biochemical recurrence after radical pros
Autor:
Marika Nespi, Elizabeth A. Burton, Heidi Carias, Adhirai Marimuthu, Glenn Michelson, Gabriel Tinoco, Rafe Shellooe, Andrew J. Wagner, Prabha N. Ibrahim, Laura Sanftner, Garson Tsang, Guoxian Wu, Wayne Spevak, Jack Lin, Anthony F. Shields, Jonathan C. Trent, Gaston Habets, Paul Severson, Rashmi Chugh, Oscar Alcantar, Amita Patnaik, Ying Zhang, Athanasios C. Tsiatis, Todd Ewing, Kerry Inokuchi, Gideon Bollag, James Tsai, Hamid Rezaei, William D. Tap, Bernice Matusow, Katrina Chan, Chao Zhang
Publikováno v:
JAMA Oncol
Importance Many cancer subtypes, including KIT-mutant gastrointestinal stromal tumors (GISTs), are driven by activating mutations in tyrosine kinases and may initially respond to kinase inhibitors but frequently relapse owing to outgrowth of heteroge
Autor:
Alice S. Mims, Melhem Solh, Uma Borate, Naveen Pemmaraju, Gautam Borthakur, Gail J. Roboz, Ben Powell, Paul Severson, Bernice Matusow, Jason Halladay, Ching Hsu, Paul Watkins, Chao Zhang, Jackie M. Walling, Athanasios C. Tsiatis, Amy E. DeZern
Publikováno v:
Blood. 136:14-15
Background: Relapsed and refractory myeloid malignancies including myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) remain a clinical challenge due to high morbidity and mortality as well as a paucity of effective therapeutic agents. P
Autor:
Paul Watkins, Athanasios C. Tsiatis, Michael Sterba, Michael S. Gordon, Bernice Matusow, Kerry Inokuchi, Chao Zhang, Jacqueline M. Walling, Alexander I. Spira, Richard D. Carvajal, Ben Powell, Marilyn Huang, Jason Halladay, Chelsea L. Hope, Amita Patnaik
Publikováno v:
Journal of Clinical Oncology. 39:3018-3018
3018 Background: PLX2853 is a potent, orally active small molecule BET inhibitor. Its unique pharmacokinetic (PK) profile is associated with less thrombocytopenia and improved tolerability by allowing transient target engagement with a prolonged phar
Autor:
Marc Olivier Timsit, Christer Svedman, Dejan Knezevic, Ming Zhou, Thierry Lebret, Virginie Verkarre, Bernard Escudier, Audrey Goddard, Hakan Aydin, Serge Koscielny, Margarita Lopatin, Yann Neuzillet, Arnaud Mejean, Athanasios C. Tsiatis, Jean-Francois Martini, Steven C. Campbell, Michael Bonham, Tara Maddala, Paul Elson, Brian I. Rini, Camelia Radulescu, Isabelle Hemmerle, J. Andrew Williams
Publikováno v:
The Lancet Oncology. 16:676-685
Summary Background The likelihood of tumour recurrence after nephrectomy in localised clear cell renal cell carcinoma is well characterised by clinical and pathological parameters. However, these assessments can be improved and personalised by the ad