Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Athanasia Koutsouris"'
Publikováno v:
BioTechniques, Vol 29, Iss 3, Pp 514-522 (2000)
Pathogenic microbes influence gene regulation in eukaryotic hosts. Reporter gene studies can define the roles of promoter regulatory sequences. The effect of pathogenic bacteria on reporter genes has not been examined. The aim of this study was to id
Externí odkaz:
https://doaj.org/article/4d028f1e74dc4dcdb925393f6b955643
Autor:
Steven D. Targum, Jeffrey Schappi, Athanasia Koutsouris, Runa Bhaumik, Mark H. Rapaport, Natalie Rasgon, Mark M. Rasenick
Publikováno v:
Molecular Psychiatry. 27:1640-1646
Autor:
Steven D, Targum, Jeffrey, Schappi, Athanasia, Koutsouris, Runa, Bhaumik, Mark H, Rapaport, Natalie, Rasgon, Mark M, Rasenick
Publikováno v:
Molecular psychiatry. 27(3)
In contrast to healthy controls, the heterotrimeric G protein, Gsalpha (Gsα) is ensconced predominantly in lipid rafts in subjects with major depressive disorder (MDD) resulting in impaired stimulation of adenylyl cyclase. In this small proof-of-con
Autor:
Rheinallt M. Jones, Athanasia Koutsouris, Jerrold R. Turner, V. K. Viswanathan, Jennifer Lising Roxas, Amy Bellmeyer, Sandhya V. Royan, Kanakeshwari Falzari, Ki Jong Rhee, Andrew W. Weflen, Andrew S. Neish, Amy Kim, Gail Hecht
Publikováno v:
Molecular Microbiology. 78:1232-1245
Enteric bacterial pathogens have evolved sophisticated strategies to evade host immune defences. Some pathogens deliver anti-inflammatory effector molecules into the host cell cytoplasm via a type III secretion system (T3SS). Enteropathogenic Escheri
Autor:
Sandhya V. Royan, Gail Hecht, Samuel Tesfay, Jennifer Lising Roxas, Kanakeshwari Falzari, Antoneicka L. Harris, Hao Cheng, Amy Bellmeyer, Ki-Jong Rhee, Athanasia Koutsouris
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
Shiga toxin (Stx) is implicated in the development of hemorrhagic colitis and hemolytic-uremic syndrome, but early symptoms of enterohemorrhagic Escherichia coli (EHEC) infection such as nonbloody diarrhea may be Stx independent. In this study, we de
Autor:
Gail Hecht, Andrew W. Weflen, Athanasia Koutsouris, Samantha Gruenheid, Mark Mimee, Ajitha Thanabalasuriar
Publikováno v:
Cellular Microbiology. 12:31-41
Enteropathogenic Escherichia coli (EPEC) is a diarrhoeal pathogen that adheres to epithelial cells of the small intestine and uses a type III secretion system to inject effector proteins into host cells. EPEC infection leads to disruption of host int
Autor:
Athanasia Koutsouris, Gail Hecht, Pradeep K. Dudeja, Krishnamurthy Ramaswamy, Alip Borthakur, Ravinder K. Gill, Sangeeta Tyagi, Waddah A. Alrefai
Publikováno v:
The Journal of Nutrition. 138:1355-1359
Probiotics are viable nonpathogenic microorganisms that are considered to confer health benefits to the host. Recent studies indicated that some Lactobacillus species function as probiotics and have been used as alternative treatments for diarrhea, w
Publikováno v:
Infection and Immunity. 75:2316-2324
The diarrheagenic pathogen enteropathogenic Escherichia coli (EPEC) is responsible for significant infant mortality and morbidity, particularly in developing countries. EPEC pathogenesis relies on a type III secretion system-mediated transfer of viru
Autor:
Thomas J. Hope, Tulika Sarma, Mark M. Rasenick, Jiang Zhu Yu, Aleksandar Krbanjevic, Athanasia Koutsouris
Publikováno v:
The Journal of biological chemistry. 290(16)
Signals that activate the G protein Gαs and promote neuronal differentiation evoke Gαs internalization in rat pheochromocytoma (PC12) cells. These agents also significantly increase Gαs association with microtubules, resulting in an increase in mi
Autor:
Gail Hecht, Daniel R. Clayburgh, Athanasia Koutsouris, Donnie Edward Shifflett, Jerrold R. Turner
Publikováno v:
Laboratory Investigation. 85:1308-1324
Enteropathogenic Escherichia coli (EPEC) infection disrupts tight junctions (TJs) and perturbs intestinal barrier function in vitro. E. coli secreted protein F (EspF) is, in large part, responsible for these physiological and morphological alteration