Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Atg9a"'
Autor:
Megan M. Braun, Brendan K. Sheehan, Samantha L. Shapiro, Yun Ding, C. Dustin Rubinstein, Brent P. Lehman, Luigi Puglielli
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The acetylation of autophagy protein 9 A (ATG9A) in the lumen of the endoplasmic reticulum (ER) by ATase1 and ATase2 regulates the induction of reticulophagy. Analysis of the ER-specific ATG9A interactome identified calreticulin (CALR), an E
Externí odkaz:
https://doaj.org/article/d24d33a0c06c4f248fa721c030b43bd0
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-5 (2024)
Abstract ATG9A is the only integral membrane protein among core autophagy-related (ATG) proteins. We previously found that ATG9A does not co-assemble into synaptophysin-positive vesicles, but rather, localizes to a distinct pool of vesicles within sy
Externí odkaz:
https://doaj.org/article/51c92ab5e93849098176c7bb59f90ac6
Publikováno v:
Autophagy Reports, Vol 3, Iss 1 (2024)
Neurons are highly differentiated and compartmentalized cells that conduct cellular processes in a spatiotemporally regulated manner. Autophagy in neurons occurs locally under stimulation and contributes to synaptic plasticity. Little is known about
Externí odkaz:
https://doaj.org/article/b4cea8d474374d2c917fb21001b51c33
Autor:
Jiaming Nie, Shaoyang Ma, Linyue Wu, Ye Li, Jiao Cao, Meng Li, Peter Mei, Paul R. Cooper, Ang Li, Dandan Pei
Publikováno v:
Advanced Science, Vol 11, Iss 44, Pp n/a-n/a (2024)
Abstract Autophagy plays an important role in determining stem‐cell differentiation. During the osteogenic differentiation of mesenchymal stem cells (MSCs), autophagosome formation is upregulated but the reason is unknown. A long‐standing quest i
Externí odkaz:
https://doaj.org/article/2b28ab1aa10d45bdaa266ca07c90ac2a
Autor:
Yujia Liu, Qing Li, Luo Fang, Xiaoping Hu, Zongfu Pan, Qing Hu, Mengting Cheng, Xinyu Tao, Yiwen Zhang, Ping Huang
Publikováno v:
Journal of Functional Foods, Vol 122, Iss , Pp 106463- (2024)
Colorectal cancer is one of the most common cancers and the main causes of mortality around the world and Oxaliplatin is a first-line chemotherapy agent for treatment of CRC. However, the dense collagen network in tumors stroma significantly reduces
Externí odkaz:
https://doaj.org/article/69737fb03a37468db86103bc3e8a4344
Autor:
Xiaoyan Zhi, Shu Shi, Yang Li, Mingxia Ma, Yaolin Long, Chen Li, Haihu Hao, Huirong Liu, Xiaohui Wang, Li Wang
Publikováno v:
Cellular & Molecular Biology Letters, Vol 28, Iss 1, Pp 1-23 (2023)
Abstract Background Cardiomyocyte death induced by autophagy inhibition is an important cause of cardiac dysfunction. In-depth exploration of its mechanism may help to improve cardiac dysfunction. In our previous study, we found that β1-adrenergic r
Externí odkaz:
https://doaj.org/article/7ca021bc008f4de0bdada401dafd3e04
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT Chlamydia trachomatis infection can be regulated by autophagy-related (ATG) genes. Here, we found that the depletion of ATG9A, one of the core ATG genes, in HeLa cells suppressed C. trachomatis growth in the inclusion. The growth was restore
Externí odkaz:
https://doaj.org/article/bf51185f099540cbae27e5af57137ea6
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