Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Atg, autophagy related gene"'
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 5, Pp 1227-1245 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 5, Pp 1227-1245 (2021)
Autophagy is a critical cellular homeostatic mechanism, and its dysfunction is linked to invasive breast carcinoma (BRCA). Recently, several omics methods have been applied to explore autophagic regulators in BRCA; however, more reliable and robust a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e5006d7fc616dab06691f1dd1bec142
https://doi.org/10.1016/j.apsb.2020.12.013
https://doi.org/10.1016/j.apsb.2020.12.013
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 973-997 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims The functions of the liver and the intestine are closely tied in both physiological and pathologic conditions. The gut microbiota (GM) often cause deleterious effects during hepatic pathogenesis. Autophagy is essential for liver hom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5847c5c25a4c55b7146f469ae9e2e369
http://www.sciencedirect.com/science/article/pii/S2352345X20301740
http://www.sciencedirect.com/science/article/pii/S2352345X20301740
Autor:
Jae Youl Cho, Wooram Choi, Haeyeop Kim, Chang-Kyun Han, Kon Kuk Shin, Jin Kyeong Kim, Sun Hee Hyun, Yo Han Hong, Yi-Seong Kwak
Publikováno v:
Journal of Ginseng Research
Journal of Ginseng Research, Vol 45, Iss 6, Pp 717-725 (2021)
Journal of Ginseng Research, Vol 45, Iss 6, Pp 717-725 (2021)
Background Korean Red Ginseng (KRG) is a traditional herb that has several beneficial properties including anti-aging, anti-inflammatory, and autophagy regulatory effects. However, the mechanisms of these effects are not well understood. In this repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c46500d57703ff31f800284eb67484
https://pubmed.ncbi.nlm.nih.gov/34764726
https://pubmed.ncbi.nlm.nih.gov/34764726
Autor:
Rui Jia, Juan S. Bonifacino
Publikováno v:
The Journal of Biological Chemistry
Components of the autophagy machinery are subject to regulation by various posttranslational modifications. Previous studies showed that monoubiquitination of LC3B catalyzed by the ubiquitin-activating enzyme UBA6 and ubiquitin-conjugating enzyme/ubi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca6129c45e68c92ffacbe1102d7a8b94
https://pubmed.ncbi.nlm.nih.gov/33577797
https://pubmed.ncbi.nlm.nih.gov/33577797
Autor:
Naoyuki Okita, Yuka Sudo, Yuhei Mizunoe, Hiromine Yasukawa, Masaaki Komatsu, Arisa Negishi, Masaki Kobayashi, Ayana Hoshino, Daiki Natori, Shukoh Watanabe, Yoshikazu Higami
Publikováno v:
Redox Biology
Redox Biology, Vol 15, Iss C, Pp 115-124 (2018)
Redox Biology, Vol 15, Iss C, Pp 115-124 (2018)
Dysfunction of autophagy, which regulates cellular homeostasis by degrading organelles and proteins, is associated with pathogenesis of various diseases such as cancer, neurodegeneration and metabolic disease. Trehalose, a naturally occurring nontoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20769cb875708e64386013f26c149eb6
http://europepmc.org/articles/PMC5730428
http://europepmc.org/articles/PMC5730428
Autor:
Simon Wilkinson
Publikováno v:
Wilkinson, S 2019, ' Emerging Principles of Selective ER Autophagy ', Journal of Molecular Biology . https://doi.org/10.1016/j.jmb.2019.05.012
Journal of Molecular Biology
Journal of Molecular Biology
The endoplasmic reticulum (ER) is a fundamental organelle in cellular metabolism and signal transduction. It is subject to complex, dynamic sculpting of morphology and composition. Degradation of ER content has an important role to play here. Indeed,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246a9d79f96cd380e5927a63fe262605
https://hdl.handle.net/20.500.11820/5820d1dc-24f7-48aa-abb5-a702fa981686
https://hdl.handle.net/20.500.11820/5820d1dc-24f7-48aa-abb5-a702fa981686
Publikováno v:
Redox Biology, Vol 4, Iss C, Pp 184-192 (2015)
Redox Biology
Redox Biology
Cancer formation is a complex and highly regulated multi-step process which is highly dependent of its environment, from the tissue to the patient. This complexity implies the development of specific treatments adapted to each type of tumor. The init
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1650a561d85938f4573709b74d2fbad9
https://doi.org/10.1016/j.redox.2014.12.003
https://doi.org/10.1016/j.redox.2014.12.003
Autor:
Kerstin Thriene, Christian Münz, Urs Ziegler, Heike Nowag, Joern Dengjel, Bruno Guhl, Susana Romao
Publikováno v:
EBioMedicine, Vol 1, Iss 2, Pp 116-125 (2014)
EBioMedicine
EBioMedicine
Epstein Barr virus (EBV) persists as a latent herpes virus infection in the majority of the adult human population. The virus can reactivate from this latent infection into lytic replication for virus particle production. Here, we report that autopha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1df1817ae0b926addd129aab63f6f4
http://www.sciencedirect.com/science/article/pii/S2352396414000310
http://www.sciencedirect.com/science/article/pii/S2352396414000310
Publikováno v:
Clinical Science (London, England : 1979)
Sirtuins are members of the Sir2 (silent information regulator 2) family, a group of class III deacetylases. Mammals have seven different sirtuins, SIRT1–SIRT7. Among them, SIRT1, SIRT3 and SIRT6 are induced by calorie restriction conditions and ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4055ae0b65db646f19c8a4a1d9c7496
https://doi.org/10.1042/cs20120190
https://doi.org/10.1042/cs20120190
Autor:
Suresh, Kumar, Santosh Kumar, Guru, Anup Singh, Pathania, Nagaraju, Mupparapu, Ajay, Kumar, Fayaz, Malik, Sandip B, Bharate, Qazi, Naveed Ahmed, Ram A, Vishwakarma, Shashi, Bhushan
Publikováno v:
Toxicology Reports
Graphical abstract
Crosstalk between apoptosis and autophagy is budding as one of the novel strategies in the cancer therapeutics. The present study tinted toward the interdependence of autophagy and apoptosis induce by a novel quinazolinone der
Crosstalk between apoptosis and autophagy is budding as one of the novel strategies in the cancer therapeutics. The present study tinted toward the interdependence of autophagy and apoptosis induce by a novel quinazolinone der
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3137b3e37511ea82caa07d3b435a6dfd
https://pubmed.ncbi.nlm.nih.gov/28962314
https://pubmed.ncbi.nlm.nih.gov/28962314