Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Atesh Worthington"'
Publikováno v:
Stem Cell Reports
Summary Age-related morbidity is associated with a decline in hematopoietic stem cell (HSC) function, but the mechanisms of HSC aging remain unclear. We performed heterochronic HSC transplants followed by quantitative analysis of cell reconstitution.
Autor:
Barbara Shapleigh, Benny Mosqueira, Mays Mohammed Salih, Valeriya Smaliy, Atesh Worthington, Haley Halasz, E. Camilla Forsberg, Lucas Seninge, Susan Carpenter, Elektra K. Robinson, Donna M. Poscablo
Publikováno v:
J Immunol
Journal of immunology (Baltimore, Md. : 1950), vol 208, iss 8
Journal of immunology (Baltimore, Md. : 1950), vol 208, iss 8
Our respiratory system is vital to protect us from the surrounding nonsterile environment; therefore, it is critical for a state of homeostasis to be maintained through a balance of inflammatory cues. Recent studies have shown that actively transcrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5c11c96754971574d2dddd1ebda523
https://europepmc.org/articles/PMC9038212/
https://europepmc.org/articles/PMC9038212/
Autor:
Forsberg Ec, Anna E. Beaudin, Atesh Worthington, Donna M. Poscablo, Taylor Cool, Adeel Hussaini
Traditional, adult-derived lymphocytes that circulate provide adaptive immunity to infection and pathogens. However, subsets of lymphoid cells are also found in non-lymphoid tissues and are called tissue-resident lymphoid cells (TLCs). TLCs encompass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24abb3c2ecc6760a4ea7bba8068aeb86
https://doi.org/10.1101/2021.07.13.452134
https://doi.org/10.1101/2021.07.13.452134
Publikováno v:
Exp Hematol
Respiratory diseases are a leading cause of death worldwide, with highly varied vulnerability to disease between individuals. The underlying reasons of disease susceptibility are unknown, but often include a variable immune response in lungs. Recentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6d8d7adb48f6f9057ffde8426cab11
https://escholarship.org/uc/item/2z41v9dx
https://escholarship.org/uc/item/2z41v9dx
Respiratory diseases are a leading cause of death worldwide, with highly varied vulnerability to disease between individuals. The underlying reasons of disease susceptibility are unknown, but often include a variable immune response in lungs. Recentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::980af3f37a1cb8b5ef84a5b6dbbfaa5c
https://doi.org/10.1101/2020.09.02.280362
https://doi.org/10.1101/2020.09.02.280362
Publikováno v:
Experimental Hematology. 111:S160
Autor:
Donna Poscablo, Atesh Worthington, Stephanie Smith-Berdan, Raymond Adili, Michael Holinstat, Camilla Forsberg
Publikováno v:
Experimental Hematology. 111:S127
Publikováno v:
Experimental Hematology. 100:S29
Autor:
Anna E. Beaudin, Gabriel Leung, Clint H. Valencia, E. Camilla Forsberg, Atesh Worthington, Taylor Cool
The discovery of a fetal origin for tissue-resident macrophages (trMacs) has inspired an intense search for the mechanisms underlying their development. Here, we performed in vivo lineage tracing of cells with an expression history of IL-7Rα, a mark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab0f8eb9337a39594efe94f76e783173
Publikováno v:
Experimental Hematology. 88:S47
Our goal is to define the cellular and molecular mechanisms that control aging of the hematopoietic system. Given the increasing global life expectancy of people and the prevalence of age-related hematological diseases, understanding alterations to s