Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Atefeh Khakpoor"'
Autor:
Sriram Narayanan, Veonice Bijin Au, Atefeh Khakpoor, Cheng Yan, Patricia J. Ahl, Nivashini Kaliaperumal, Bernett Lee, Wen Wei Xiang, Juling Wang, Chris Lee, Amy Tay, Seng Gee Lim, John E. Connolly
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Our objective was to examine differences in cytokine/chemokine response in chronic hepatitis B(CHB) patients to understand the immune mechanism of HBsAg loss (functional cure) during antiviral therapy. We used an unbiased machine learning st
Externí odkaz:
https://doaj.org/article/dd17137d36974df3b1796e6222c13612
Publikováno v:
Viruses, Vol 13, Iss 3, p 524 (2021)
Background: Interaction between host transcription factors (TFs) and the viral genome is fundamental for hepatitis B virus (HBV) gene expression regulation. Additionally, the distinct interaction of the TFs’ network with the HBV genome determines t
Externí odkaz:
https://doaj.org/article/0d14df68e5f34395bf2fd33eabd9dc8b
Publikováno v:
Journal of Hepatology. 78:731-741
Hepatitis B core-related antigen(HBcrAg) is a new biomarker for Chronic Hepatitis B(CHB) but its performance has not been critically or systematically appraised.We evaluated the biological pathway of HBcrAg, and performed a systematic review of PubMe
Autor:
Balakrishnan Chakrapani Narmada, Atefeh Khakpoor, Niranjan Shirgaonkar, Sriram Narayanan, Pauline Poh Kim Aw, Malay Singh, Kok Haur Ong, Collins Oduor Owino, Jane Wei Ting Ng, Hui Chuing Yew, Nu Soibah Binte Mohamed Nasir, Veonice Bijin Au, Reina Sng, Nivashini Kaliaperumal, Htet Htet Toe Wai Khine, Hui Xin Ng, Su Li Chia, Cindy Xin Yi Seah, Myra HJ Alnawaz, Chris Lee Yoon Wai, Amy Yuh Ling Tay, Weimiao Yu, John Edward Connolly, Giridharan Periyasamy, Seng Gee Lim, Ramanuj Dasgupta
Hepatitis B surface antigen (HBsAg) loss or functional cure (FC), is considered the desirable therapeutic outcome for chronic hepatitis B (CHB) patients. However, the immuno-pathological biomarkers and underlying mechanisms remain unclear. Here we pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fed587114bdba974912ed8bd5f397fe
https://doi.org/10.1101/2022.04.26.489625
https://doi.org/10.1101/2022.04.26.489625
Publikováno v:
Journal of Hepatology. 77:S298
Autor:
Cameron Soulette, Lindsey May, Atefeh Khakpoor, Dong Han, Ricardo Ramirez, Narmada Balakrishnan, Nicholas Van Buuren, Ramanuj Dasgupta, Vithika Suri, Li Li, Hongmei Mo, Becket Feierbach, Jeffrey Wallin, Seng Gee Lim
Publikováno v:
Journal of Hepatology. 77:S247
Autor:
Wen Wei Xiang, Veonice Bijin Au, Amy Tay, Atefeh Khakpoor, John E. Connolly, Cheng Yan, Seng Gee Lim, Bernett Lee, Patricia J. Ahl, Juling Wang, Chris C. Lee, Nivashini Kaliaperumal, Sriram Narayanan
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Our objective was to examine differences in cytokine/chemokine response in chronic hepatitis B(CHB) patients to understand the immune mechanism of HBsAg loss (functional cure) during antiviral therapy. We used an unbiased machine learning strategy to
Autor:
Laura Rivino, Florent Ginhoux, Antonio Bertoletti, Charles-Antoine Dutertre, Evan W. Newell, Nasirah Banu, Dahai Zheng, Atefeh Khakpoor, Erica Ceccarello, Qingfeng Chen, Michelle Hong, Anthony T. Tan, Seng Gee Lim, Christine Y.L. Tham, Kang Hoe Lee, Adeline Chia, Juandy Jo, Norman Pavelka, Lu-En Wai, Jinmiao Chen, Alfonso Tan-Garcia, Choong Tat Keng, K.C. Tan
Publikováno v:
Journal of Hepatology. 67:490-500
Background & Aims Liver inflammation is key in the progression of chronic viral hepatitis to cirrhosis and hepatocellular carcinoma. The magnitude of viral replication and the specific anti-viral immune responses should govern the degree of inflammat
Spatiotemporal Differences in Presentation of CD8 T Cell Epitopes during Hepatitis B Virus Infection
Autor:
Patrick T F Kennedy, Zi Zong Ho, Ninghan Yang, Jia Xin Chow, Yi Ni, Atefeh Khakpoor, Stephan Urban, Antonio Bertoletti, Anthony T. Tan, Reshmi Giri, Vincent Yi Sheng Oei, Antony K. Chen, Mala K. Maini
Publikováno v:
Journal of Virology
The inability of patients with chronic HBV infection to clear HBV is associated with defective HBV-specific CD8+ T cells. Hence, the majority of immunotherapy developments focus on HBV-specific T cell function restoration. However, knowledge of wheth
Publikováno v:
Viruses, Vol 13, Iss 524, p 524 (2021)
Viruses
Volume 13
Issue 3
Viruses
Volume 13
Issue 3
Background: Interaction between host transcription factors (TFs) and the viral genome is fundamental for hepatitis B virus (HBV) gene expression regulation. Additionally, the distinct interaction of the TFs’ network with the HBV genome determines t