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Akademický článek

Relationship Between Arterial Stiffness Index, Pulse Pressure, and Magnetic Resonance Imaging Markers of White Matter Integrity: A UK Biobank Study

Autor: Atef Badji, Julien Cohen-Adad, Hélène Girouard

Publikováno v: Frontiers in Aging Neuroscience, Vol 14 (2022)

BackgroundAlzheimer’s disease and dementia in general constitute one of the major public health problems of the 21st century. Research in arterial stiffness and pulse pressure (PP) play an important role in the quest to reduce the risk of developin

Externí odkaz: https://doaj.org/article/91879b45006847359b8330634ceddd2c

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Akademický článek

Cerebrospinal Fluid Biomarkers, Brain Structural and Cognitive Performances Between Normotensive and Hypertensive Controlled, Uncontrolled and Untreated 70-Year-Old Adults

Autor: Atef Badji, Joana B. Pereira, Sara Shams, Johan Skoog, Anna Marseglia, Konstantinos Poulakis, Lina Rydén, Kaj Blennow, Henrik Zetterberg, Silke Kern, Anna Zettergren, Lars-Olof Wahlund, Hélène Girouard, Ingmar Skoog, Eric Westman

Publikováno v: Frontiers in Aging Neuroscience, Vol 13 (2022)

Background: Hypertension is an important risk factor for Alzheimer’s disease (AD). The pathophysiological mechanisms underlying the relationship between AD and hypertension are not fully understood, but they most likely involve microvascular dysfun

Externí odkaz: https://doaj.org/article/52ea82fe5fce4b56af5c959aa2c80203

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Akademický článek

Arterial stiffness cut-off value and white matter integrity in the elderly

Autor: Atef Badji, Adrián Noriega de la Colina, Agah Karakuzu, Tanguy Duval, Laurence Desjardins-Crépeau, Matthieu Parizet, Sven Joubert, Louis Bherer, Maxime Lamarre-Cliche, Nikola Stikov, Julien Cohen-Adad, Hélène Girouard

Publikováno v: NeuroImage: Clinical, Vol 26, Iss , Pp - (2020)

Objective: Central artery stiffness is a confirmed predictor of cardiovascular health status that has been consistently associated with cognitive dysfunction and dementia. The European Society of Hypertension has established a threshold of arterial s

Externí odkaz: https://doaj.org/article/f56e815439154d478e697f7065eb52e6

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Cerebrovascular damage in subjective cognitive decline: A systematic review and meta-analysis

Autor: Helda Pitti, Patricia Diaz-Galvan, José Barroso, Atef Badji, Jonas K. Olofsson, Eric Westman, Daniel Ferreira, Nira Cedres

Publikováno v: Ageing research reviews. 82

Subjective cognitive decline (SCD) has been postulated as an early marker of Alzheimer's Disease (AD) but it can also be associated to other non-AD pathologies such as Vascular Dementia (VaD). Nevertheless, there is scarce data about SCD as a potenti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b8301a9b7226b8274f7a2eb1f7e448
https://pubmed.ncbi.nlm.nih.gov/36240992

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Associations Between Relative Morning Blood Pressure, Cerebral Blood Flow, and Memory in Older Adults Treated and Controlled for Hypertension

Autor: Maxime Lamarre-Cliche, Adrián Noriega de la Colina, Hélène Girouard, Christine Gagnon, Louis Bherer, Julien Cohen-Adad, Marie-Christine Robitaille-Grou, Tommy Boshkovski, Sven Joubert, Atef Badji, Claudine J. Gauthier

Publikováno v: Hypertension. 77:1703-1713

Hypertension, elevated morning blood pressure (BP) surges, and circadian BP variability constitute risk factors for cerebrovascular events. Nevertheless, while evidence indicates that hypertension is associated with cognitive dysfunctions, the link b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1320ec5e34d63c6a65462901039072a2
https://doi.org/10.1161/hypertensionaha.120.16124

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A Cross-Sectional Study on the Impact of Arterial Stiffness on the Corpus Callosum, a Key White Matter Tract Implicated in Alzheimer’s Disease

Autor: Atef Badji, Adrián Noriega de la Colina, Maxime Lamarre-Cliche, Nikola Stikov, Hélène Girouard, Charley Gros, Marie-Christine Robitaille-Grou, Julien Cohen-Adad, Louis Bherer, Tommy Boshkovski, Sven Joubert, Agah Karakuzu, Claudine J. Gauthier, Dalia Sabra

Publikováno v: Journal of Alzheimer's Disease. 77:591-605

Background: Vascular risk factors such as arterial stiffness play an important role in the etiology of Alzheimer’s disease (AD), presumably due to the emergence of white matter lesions. However, the impact of arterial stiffness to white matter stru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b5243bffa705d07ff58055edb3f2e7
https://doi.org/10.3233/jad-200668

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Multiple sclerosis lesions in motor tracts from brain to cervical cord: spatial distribution and correlation with disability

Publikováno v: Brain-A Journal of Neurology
Brain-A Journal of Neurology, Oxford University Press (OUP), 2020, 143 (7), pp.2089-2105. ⟨10.1093/brain/awaa162⟩
Brain
Brain-A Journal of Neurology, 2020, 143 (7), pp.2089-2105. ⟨10.1093/brain/awaa162⟩

Despite important efforts to solve the clinico-radiological paradox, correlation between lesion load and physical disability in patients with multiple sclerosis remains modest. One hypothesis could be that lesion location in corticospinal tracts play

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c1f1adab04e3dbbaea25a7e2ddf4e37
https://doi.org/10.1093/brain/awaa162

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Diurnal blood pressure loads are associated with lower cognitive performances in controlled-hypertensive elderly individuals

Autor: Rong Wu, Louis Bherer, Atef Badji, Julien Doyon, Laurence Desjardins-Crépeau, Maxime Lamarre-Cliche, Hélène Girouard, Adrián Noriega de la Colina

Publikováno v: Journal of Hypertension. 37:2168-2179

INTRODUCTION Hypertension in midlife adults is associated with cognitive decline later in life. In individuals treated for hypertension, blood pressure (BP) loads have been associated with end organ damages. This study examines whether BP load invers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::730a10075f9fee98ea8e74dad8e9e973
https://doi.org/10.1097/hjh.0000000000002155

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