Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Atanu, Chakraborty"'
Publikováno v:
Asian Journal of Medical Sciences, Vol 14, Iss 9, Pp 97-102 (2023)
Background: Metabolic Syndrome (MetS) (Syndrome X, insulin resistance syndrome, MetS) consists of a constellation of metabolic abnormalities which include central obesity, hyperglycemia, insulin resistance, high triglycerides, low high-density lipopr
Externí odkaz:
https://doaj.org/article/f61eb9e2cfd841f39589360ef3af6eb1
Publikováno v:
Acta Medica International, Vol 10, Iss 2, Pp 131-136 (2023)
Introduction: The prevalence of obesity among women is an increasing problem, especially in urban population due to sedentary lifestyles and altered dietary habits. Maternal obesity has consequences on pregnancy and perinatal outcome. The present stu
Externí odkaz:
https://doaj.org/article/fdd08f7ea66b4aada83456fa935b5855
Autor:
Tereza Vaclova, Atanu Chakraborty, James Sherwood, Sarah Ross, Danielle Carroll, J. Carl Barrett, Julian Downward, Elza C. de Bruin
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The development of covalent inhibitors against KRAS G12C represents a major milestone in treatment of RAS-driven cancers, especially in non-small cell lung cancer (NSCLC), where KRAS G12C is one of the most common oncogenic driver. Here we i
Externí odkaz:
https://doaj.org/article/80183fd1fcb54089bce08329d47a9691
Autor:
E. Josue Ruiz, Linxiang Lan, Markus Elmar Diefenbacher, Eva Madi Riising, Clive Da Costa, Atanu Chakraborty, Joerg D. Hoeck, Bradley Spencer-Dene, Gavin Kelly, Jean-Pierre David, Emma Nye, Julian Downward, Axel Behrens
Publikováno v:
JCI Insight, Vol 6, Iss 13 (2021)
The AP-1 transcription factor c-Jun is required for Ras-driven tumorigenesis in many tissues and is considered as a classical proto-oncogene. To determine the requirement for c-Jun in a mouse model of K-RasG12D–induced lung adenocarcinoma, we induc
Externí odkaz:
https://doaj.org/article/d1bdf75630574d7b9e1c28b13a237cf7
Publikováno v:
Journal of Tissue Engineering, Vol 11 (2020)
Brain diseases including neurodegenerative disorders and tumours are among the most serious health problems, degrading the quality of life and causing massive economic cost. Nanoparticles that load and deliver drugs and genes have been intensively st
Externí odkaz:
https://doaj.org/article/dc9080902eed4379876d6143909adf24
Autor:
Sarah Ross, Michael Niedbala, Sabina Cosulich, Zoe Underwood, Eleanor Wigmore, Alison Peter, Carla P. Martins, Lukasz Magiera, Jason G. Kettle, Giovanni Ciotta, Ivan del Barco Barrantes, Tamara Baker, James Atkinson, Alex Koers, Rebecca Whiteley, Radoslaw Polanski, Michael Davies, Sue Bickerton, Hilary Lewis, David Robinson, Lyndsey Hanson, Atanu Chakraborty
Supplementary Data from AZD4625 is a Potent and Selective Inhibitor of KRASG12C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af8725b786ab7b470d22cf3bb924324
https://doi.org/10.1158/1535-7163.22523586.v1
https://doi.org/10.1158/1535-7163.22523586.v1
Autor:
Sarah Ross, Michael Niedbala, Sabina Cosulich, Zoe Underwood, Eleanor Wigmore, Alison Peter, Carla P. Martins, Lukasz Magiera, Jason G. Kettle, Giovanni Ciotta, Ivan del Barco Barrantes, Tamara Baker, James Atkinson, Alex Koers, Rebecca Whiteley, Radoslaw Polanski, Michael Davies, Sue Bickerton, Hilary Lewis, David Robinson, Lyndsey Hanson, Atanu Chakraborty
Supplementary Figure from AZD4625 is a Potent and Selective Inhibitor of KRASG12C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::040a8dea15a3d11c94aef8426fadb286
https://doi.org/10.1158/1535-7163.22523583
https://doi.org/10.1158/1535-7163.22523583
Autor:
Jason G. Kettle, Sharan K. Bagal, Sue Bickerton, Michael S. Bodnarchuk, Scott Boyd, Jason Breed, Rodrigo J. Carbajo, Doyle J. Cassar, Atanu Chakraborty, Sabina Cosulich, Iain Cumming, Michael Davies, Nichola L. Davies, Andrew Eatherton, Laura Evans, Lyman Feron, Shaun Fillery, Emma S. Gleave, Frederick W. Goldberg, Lyndsey Hanson, Stephanie Harlfinger, Martin Howard, Rachel Howells, Anne Jackson, Paul Kemmitt, Gillian Lamont, Scott Lamont, Hilary J. Lewis, Libin Liu, Michael J. Niedbala, Christopher Phillips, Radek Polanski, Piotr Raubo, Graeme Robb, David M. Robinson, Sarah Ross, Matthew G. Sanders, Michael Tonge, Rebecca Whiteley, Stephen Wilkinson, Junsheng Yang, Wenman Zhang
Publikováno v:
Journal of Medicinal Chemistry. 65:6940-6952
Autor:
Axel Behrens, Martin Eilers, Nikita Popov, Richard Mitter, Sophia M. Blake, Atanu Chakraborty, Markus E. Diefenbacher
Legends for Supplementary Figures S1-S4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82cfbc4b2047b90cb88e6296f11d2941
https://doi.org/10.1158/0008-5472.22406438.v1
https://doi.org/10.1158/0008-5472.22406438.v1
Autor:
Axel Behrens, Martin Eilers, Nikita Popov, Richard Mitter, Sophia M. Blake, Atanu Chakraborty, Markus E. Diefenbacher
The stability of several oncoproteins, including c-Myc, is regulated by ubiquitin-dependent degradation mediated by the SCF(Fbw7) ubiquitin ligase. This activity is antagonized by the deubiquitinase Usp28, which is highly expressed in murine and huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f142e30006fb2efeb3296b9cb7d053
https://doi.org/10.1158/0008-5472.c.6507074
https://doi.org/10.1158/0008-5472.c.6507074