Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Atanas Nankov"'
Publikováno v:
Scopus-Elsevier
A series of seven new cephalosporins was prepared for preliminary microbiological evaluation by N-acylation of 7-aminoce-phalosporanic acid with substituted N-pyrrolylcarboxylic acids via mixed anhydrides. The chemical structure of the compounds were
Publikováno v:
Archiv der Pharmazie. 339(3)
The analgesic activity of nine substituted N-pyrrolylcarboxylic acids, previously reported as anti-inflammatory agents, has been evaluated. The effects on nociception were examined in male Wistar rats by the Randall-Selitto paw-pressure test. The com
Publikováno v:
Farmaco (Societa chimica italiana : 1989). 60(3)
The present study focuses on development of new potential inhibitors of cyclooxygenase-2 (COX-2): series of N-pyrrolylcarboxylic acids. 3D-QSAR (Quantitative Structure-Activity Relationship) CoMFA (Comparative Molecular Field Analysis) and CoMSIA (Co