Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Atanas D. Krustev"'
Publikováno v:
European Journal of Pharmacology. 498:233-239
Galantamine is efficacious for vascular dementia and Alzheimer's disease. Its application leads to some negative gastrointestinal side effects. The present study observes galantamine-induced influence on gastrointestinal motility of rats and its effe
Autor:
Damyanka P Getova, Raina G. Ardasheva, Mariana D. Argirova, Valentin I. Turiiski, Atanas D. Krustev, Natalia A Prisadova
Publikováno v:
Folia Medica. 53
Aim To find if tacrine exerts a sensitizing effect on the cholinergic receptors of gastric smooth muscles, and study some of the mechanisms inducing it and measure the relative intensity of tacrine's effects on contractile activity. Material and meth
Publikováno v:
Canadian journal of physiology and pharmacology. 84(11)
Tacrine, a non-competitive reversible acetylcholinesterase and butyrylcholineserase inhibitor, caused a concentration-dependent tonic contraction of gastric smooth muscle preparations in the concentration range 1 × 10−7 mol/L – 1 × 10−5 mol/L
Publikováno v:
Folia medica. 47(2)
Tacrine is a cholinesterase inhibitor used for the treatment of Alzheimer's disease. The drug also has an effect on a number of tissues and organs that are not targets of its therapeutical action in this disease. The gastrointestinal tract is one suc