Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Atanas Chapkanov"'
Autor:
Atanas Chapkanov, Terry W. Schultz, Darina Yordanova, Kalin Kirilov, Hristiana Ivanova, Ovanes G. Mekenyan
Publikováno v:
Regulatory Toxicology and Pharmacology. 139:105357
Autor:
Atanas Chapkanov, Louise Camenzuli, Todor Pavlov, Ovanes G. Mekenyan, Timothy J. Patterson, Darina Yordanova, Colin M. North
Publikováno v:
Environmental toxicology and chemistryREFERENCES. 40(11)
Many of the newly produced and registered substances are complex mixtures or substances of unknown or variable composition, complex reaction products, and biological materials (UVCBs). The latter often consist of a large number of constituents, some
Autor:
Todor Pavlov, Atanas Chapkanov, Marin Georgiev, Ovanes G. Mekenyan, Andrea Gissi, Chanita Kuseva, Georgi Chankov, Hristiana Ivanova, Darina Yordanova, Tomasz Sobanski, Terry W Schultz, Ksenia Tankova
Publikováno v:
Computational Toxicology. 11:65-71
Read-across is an alternative or supplementary method to the use of test results (including test results from tests employing laboratory animals) for chemical hazard assessment. Its use by both the industrial and the regulatory communities has increa
Autor:
Tomasz Sobanski, Marin Georgiev, Atanas Chapkanov, Chanita Kuseva, Ksenia Tankova, Todor Pavlov, Terry W Schultz, Stela Kutsarova, Ovanes G. Mekenyan, Darina Yordanova, Andrea Gissi
Publikováno v:
Regulatory Toxicology and Pharmacology. 105:51-61
The Read-Across Assessment Framework (RAAF) was developed by the European Chemicals Agency (ECHA) as an internal tool providing a framework for a consistent, structured and transparent assessment of grouping of chemicals and read-across. Following a
Autor:
Stanislav Temelkov, Chanita Kuseva, Irina Dermen, Darina Yordanova, Marin Georgiev, Ksenia Tankova, Andrea Gissi, Atanas Chapkanov, Tomasz Sobanski, Hristiana Ivanova, Todor Pavlov, Ovanes G. Mekenyan, Terry W Schultz
Publikováno v:
Computational Toxicology. 10:89-104
Toxicological understanding and computational possibilities progress every year. The OECD QSAR Toolbox, an in silico system for predicting toxicity of chemicals, is regularly updated with up to data knowledge and functionalities. This expansion has m
Autor:
Chanita Kuseva, Valentin Marinov, Todor Pavlov, Todor Petkov, Atanas Chapkanov, Detelina Dimitrova, Tobias Wombacher, Sarah Mullen-Hinkle, Wisdom Zhu, Michael Siebold, Ovanes Mekenyan
Publikováno v:
Computational Toxicology. 23:100230
Publikováno v:
Computational Toxicology. 22:100219
Autor:
Darina Yordanova, Stela Kutsarova, Chanita Kuseva, Ovanes G. Mekenyan, Stoyanka Stoeva, Aycel Mehmed, Atanas Chapkanov, Todor Petkov, Terry W Schultz, Daniela Cherkezova, Marin Georgiev
Publikováno v:
Computational Toxicology. 20:100194
As modules in the QSAR Toolbox become automated, operator control is diminished. Therefore, it becomes more crucial that evidence be provided that reveals the software meets the specification intended by the developers (i.e., verification) and the re
Autor:
Stoyanka Stoeva, Marin Georgiev, Daniela Cherkezova, Stela Kutsarova, Ovanes G. Mekenyan, Todor Petkov, Atanas Chapkanov, Terry W Schultz, Aycel Mehmed
Publikováno v:
Regulatory Toxicology and Pharmacology. 125:105015
A decision-scheme outlining the steps for identifying the appropriate chemical category and subsequently appropriate tested source analog(s) for data gap filling of a target chemical by read-across is described. The primary features used in the group
Autor:
Ovanes G. Mekenyan, Yordan H. Karakolev, N. D. Todorova, Todor Pavlov, Stanislav Temelkov, Chanita Kuseva, K. Gerova, R Vasilev, Tomasz Sobanski, Mike Rasenberg, S. Dimitrov, Atanas Chapkanov, Georgi Chankov, Robert Diderich, Aycel Mehmed
Publikováno v:
SAR and QSAR in Environmental Research. 27:203-219
The OECD QSAR Toolbox is a software application intended to be used by governments, the chemical industry and other stakeholders in filling gaps in (eco)toxicity data needed for assessing the hazards of chemicals. The development and release of the T