Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Atanas Bijev"'
Publikováno v:
Folia Medica, Vol 60, Iss 2, Pp 270-274 (2018)
Background: Persisting inflammatory stimuli cause chronic inflammation recognized as the major factor contributing to the development of a number of diseases. One group of drugs used in the treatment of chronic inflammation is the group of non-steroi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00debb0041be455c05b6cc350f6fb13d
http://www.degruyter.com/view/j/folmed.2017.60.issue-2/folmed-2017-0095/folmed-2017-0095.xml?format=INT
http://www.degruyter.com/view/j/folmed.2017.60.issue-2/folmed-2017-0095/folmed-2017-0095.xml?format=INT
Publikováno v:
CBU International Conference Proceedings. 5:1083-1091
This research aims to contribute to the global search for more effective tuberculostatics that has been triggered by recent outbreaks of tuberculosis. A group of pyrrole-containing derivatives are designed and theoretically elucidated. The identifica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b817e85a3ccabe6bc485d044b145bbb6
https://doi.org/10.12955/cbup.v5.1075
https://doi.org/10.12955/cbup.v5.1075
Autor:
Atanas Bijev, Stanislava Vladimirova, Delian Delev, Ivanka I. Kostadinova, H. Zlatanova, Tanya Deneva, Ilia Kostadinov
Publikováno v:
International Journal of Pain Management. 1:1-11
The objective of our study was to evaluate the analgesic and anti-inflammatory activity, as well as possible organ toxicity of 2-3-3-methyl-pentanoic acid (compound 3d), a newly synthesized pyrrolic derivative, structurally similar to Celecoxib. Anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f76dce3b4b5656e9b0d71a203f89d544
https://doi.org/10.14302/issn.2688-5328.ijp-17-1600
https://doi.org/10.14302/issn.2688-5328.ijp-17-1600
Autor:
D. Delev, Atanas Bijev, Stanislava Vladimirova, H. Zlatanova, Ilia Kostadinov, Ivanka I. Kostadinova, I. Kandilarov
Publikováno v:
European Neuropsychopharmacology. 29:S468-S469
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f283bec2efdc61910f53788a66168ec4
https://doi.org/10.1016/j.euroneuro.2018.11.700
https://doi.org/10.1016/j.euroneuro.2018.11.700
An access to new N-pyrrolylcarboxylic acids as potential COX-2 inhibitors via Paal-Knorr cyclization
Autor:
Atanas Bijev, Stanislava Vladimirova
Publikováno v:
Heterocyclic Communications. 20:111-115
Twenty new N-pyrrolylcarboxylic acids were designed to assume the architecture of contemporary selective COX-2 inhibitors as potential anti-inflammatory agents. The targeted products were synthesized in 70–82% yields by Paal-Knorr cyclization of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dec0fe0e3d22715ab3f51a842b804cb
https://doi.org/10.1515/hc-2014-0022
https://doi.org/10.1515/hc-2014-0022
Publikováno v:
Medicinal Chemistry. 8:462-473
Preliminary investigations of our research team have shown that some pyrrole hydrazones posses strong inhibitory activity against the tuberculosis bacilli, and thus represent a new perspective for development of anti-tuberculosis agents. In this work
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5aa337c9efd0f9d3ddf9cac1804afd2
https://doi.org/10.2174/1573406411208030462
https://doi.org/10.2174/1573406411208030462
Publikováno v:
Scopus-Elsevier
A series of seven new cephalosporins was prepared for preliminary microbiological evaluation by N-acylation of 7-aminoce-phalosporanic acid with substituted N-pyrrolylcarboxylic acids via mixed anhydrides. The chemical structure of the compounds were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b36a2e50212f923afa51cf0b33048f3
https://doi.org/10.1055/s-0031-1296946
https://doi.org/10.1055/s-0031-1296946
Autor:
Atanas Bijev
Publikováno v:
Arzneimittelforschung. 56:96-103
Five carbohydrazides and 19 hydrazones of carboxylic acids of pyrrole were synthesized as new structural analogs of known tuberculostatics, such as isoniazid (CAS 54-85-3) and its popular hydrazones. The preliminary screening against Mycobacterium tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afede83e2ec0dea1f0ecfa59459039b7
https://doi.org/10.1055/s-0031-1296708
https://doi.org/10.1055/s-0031-1296708
Publikováno v:
Arzneimittelforschung. 56:753-759
Twelve new compounds were designed as 5-aryl-1 H -pyrrole analogs of celecoxib (CAS 169590-42-5) and were synthesized by Paal-Knorr cyclization in three series according to 1 H -substitution: derivatives with salicylic acid, pyrazolone or isonicotina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5639fc8c8c8bece74106f229ec324d61
https://doi.org/10.1055/s-0031-1296786
https://doi.org/10.1055/s-0031-1296786
Autor:
Atanas Bijev
Publikováno v:
Arzneimittelforschung. 59:34-41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9380831e4d23f85a24138bbaf1ea60aa
https://doi.org/10.1055/s-0031-1296362
https://doi.org/10.1055/s-0031-1296362