Výsledky vyhledávání - "Atakpa, Peace"

Dissertation/ Thesis

Ca2+ signalling between the endoplasmic reticulum and lysosomes

Autor: Atakpa, Peace

Ca2+ is a universal and versatile intracellular messenger, regulating a vast array of biological processes due to variations in the frequency, amplitude, spatial and temporal dynamics of Ca2+ signals. Increases in cytosolic free Ca2+ concentration ([

Externí odkaz: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.763790

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Akademický článek

IP3 Receptors Preferentially Associate with ER-Lysosome Contact Sites and Selectively Deliver Ca2+ to Lysosomes

Autor: Atakpa, Peace, Thillaiappan, Nagendra Babu, Mataragka, Stefania, Prole, David L., Taylor, Colin W.

Publikováno v: In Cell Reports 11 December 2018 25(11):3180-3193

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GPN does not release lysosomal Ca2+ but evokes Ca2+ release from the ER by increasing the cytosolic pH independently of cathepsin C

Autor: Atakpa, Peace, Van Marrewijk, Laura M, Apta-Smith, Michael, Chakraborty, Sumita, Taylor, Colin W

The dipeptide glycyl-l-phenylalanine 2-naphthylamide (GPN) is widely used to perturb lysosomes because its cleavage by the lysosomal enzyme cathepsin C is proposed to rupture lysosomal membranes. We show that GPN evokes a sustained increase in lysoso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4c7be05d2bf5bf880cc4b8818b0d49

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Akademický článek

GPN does not release lysosomal Ca²⁺ but evokes Ca²⁺ release from the ER by increasing the cytosolic pH independently of cathepsin C.

Autor: Atakpa, Peace, van Marrewijk, Laura M., Apta-Smith, Michael, Chakraborty, Sumita, Taylor, Colin W.

Publikováno v: Journal of Cell Science; Feb2019, Vol. 132 Issue 3, p1-12, 12p

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Periodical

IP3Receptors Preferentially Associate with ER-Lysosome Contact Sites and Selectively Deliver Ca2+to Lysosomes

Autor: Atakpa, Peace, Thillaiappan, Nagendra Babu, Mataragka, Stefania, Prole, David L., Taylor, Colin W.

Publikováno v: Cell Reports; December 2018, Vol. 25 Issue: 11 p3180-3193.e7

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Akademický článek

GPN does not release lysosomal Ca ²⁺ but evokes Ca ²⁺ release from the ER by increasing the cytosolic pH independently of cathepsin C.

Autor: Atakpa P; Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK., van Marrewijk LM; Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK., Apta-Smith M; Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK., Chakraborty S; Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK., Taylor CW; Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK cwt1000@cam.ac.uk.

Publikováno v: Journal of cell science [J Cell Sci] 2019 Feb 01; Vol. 132 (3). Date of Electronic Publication: 2019 Feb 01.

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