7D, a small molecule inhibits dengue infection by increasing interferons and neutralizing-antibodies via CXCL4:CXCR3:p38:IRF3 and Sirt1:STAT3 axes respectively.

Autor: Gaur KK; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India., Asuru TR; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India., Srivastava M; Translational Health Science Technology Institute, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India., Singh N; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India., Purushotham N; Department of Studies in Chemistry, Mangalore University, Mangalagangotri, Karnataka, India., Poojary B; Department of Studies in Chemistry, Mangalore University, Mangalagangotri, Karnataka, India., Das B; Translational Health Science Technology Institute, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India., Bhattacharyya S; Translational Health Science Technology Institute, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India., Asthana S; Translational Health Science Technology Institute, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India. sasthana@thsti.res.in., Guchhait P; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India. prasenjit@rcb.res.in.

Publikováno v: EMBO molecular medicine [EMBO Mol Med] 2024 Oct; Vol. 16 (10), pp. 2376-2401. Date of Electronic Publication: 2024 Sep 16.

Inhibition of cellular activation induced by platelet factor 4 via the CXCR3 pathway ameliorates Japanese encephalitis and dengue viral infections.

Autor: Singh A; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India., Ghosh R; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India., Asuru TR; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India., Prajapat SK; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India., Joshi G; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India., Gaur KK; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India., Shrimali NM; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India., Ojha A; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India; Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, California, USA., Vikram NK; Division of Infectious Disease, All India Institute of Medical Sciences, New Delhi, India., Poncz M; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Kalia M; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India., Guchhait P; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India. Electronic address: prasenjit@rcb.res.in.

Publikováno v: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2024 Mar; Vol. 22 (3), pp. 818-833. Date of Electronic Publication: 2023 Nov 27.